scholarly journals Increased Hepatitis C virus screening, diagnosis and linkage to care rates among people who use drugs through a patient‐centered program from Italy

2021 ◽  
Author(s):  
Alessandra Mangia ◽  
Maria Franca Rina ◽  
Antonio Canosa ◽  
Valeria Piazzolla ◽  
Maria Maddalena Squillante ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Linkage To Care ◽  
People Who Use Drugs ◽  
Patient Centered ◽  
Virus Screening

scholarly journals Hepatitis C Virus (HCV) Care Continuum Outcomes and HCV Community Viral Loads Among Patients in an Opioid Treatment Program

2020 ◽  
Vol 222 (Supplement_5) ◽  
pp. S335-S345
Author(s):  
Ashly E Jordan ◽  
Charles M Cleland ◽  
Bruce R Schackman ◽  
Katarzyna Wyka ◽  
David C Perlman ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Viral Load ◽  
Hepatitis C ◽  
Treatment Program ◽  
Linkage To Care ◽  
People Who Use Drugs ◽  
Treatment Need ◽  
Care Continuum ◽  
Opioid Treatment ◽  
Unmet Treatment Need

Abstract Background Hepatitis C virus (HCV) remains endemic among people who use drugs (PWUD). Measures of HCV community viral load (CVL) and HCV care continuum outcomes may be valuable for ascertaining unmet treatment need and for HCV surveillance and control. Methods Data from patients in an opioid treatment program during 2013–2016 were used to (1) identify proportions of antibody and viral load (VL) tested, linked-to-care, and treated, in 2013–2014 and 2015–2016, and pre- and postimplementation of qualitative reflex VL testing; (2) calculate engaged-in-care HCV CVL and “documented” and “estimated” unmet treatment need; and (3) examine factors associated with linkage-to-HCV-care. Results Among 11 267 patients, proportions of HCV antibody tested (52.5% in 2013–2014 vs 73.3% in 2015–2016), linked-to-HCV-care (15.7% vs 51.8%), and treated (12.0% vs 44.7%) all increased significantly. Hispanic ethnicity was associated with less linkage-to-care, and Manhattan residence was associated with improved linkage-to-care. The overall engaged-in-care HCV CVL was 4 351 079 copies/mL (standard deviation = 7 149 888); local HCV CVLs varied by subgroup and geography. Documented and estimated unmet treatment need decreased but remained high. Conclusions After qualitative reflex VL testing was implemented, care continuum outcomes improved, but gaps remained. High rates of unmet treatment need suggest that control of the HCV epidemic among PWUD will require expansion of HCV treatment coverage.

scholarly journals Implementing hospital-based baby boomer hepatitis c virus screening and linkage to care: Strategies, results, and costs

2015 ◽  
Vol 10 (8) ◽  
pp. 510-516 ◽  
Author(s):  
Barbara J. Turner ◽  
Barbara S. Taylor ◽  
Joshua T. Hanson ◽  
Mary Elizabeth Perez ◽  
Ludivina Hernandez ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Baby Boomer ◽  
Linkage To Care ◽  
Virus Screening

scholarly journals High-Yield Birth-Cohort Hepatitis C Virus Screening and Linkage to Care among Underserved African Americans, Atlanta, Georgia, 2012–2013

2016 ◽  
Vol 131 (2_suppl) ◽  
pp. 84-90 ◽  
Author(s):  
Lesley S. Miller ◽  
Francois Rollin ◽  
Shelly-Ann Fluker ◽  
Kristina L. Lundberg ◽  
Brandi Park ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
African Americans ◽  
Birth Cohort ◽  
Linkage To Care ◽  
High Yield ◽  
Virus Screening

scholarly journals A Feasibility Study to Increase Chronic Hepatitis C Virus RNA Testing and Linkage to Care among Clients Attending Homeless Services in Amsterdam, The Netherlands

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1197
Author(s):  
Ellen Generaal ◽  
Hilje Logtenberg van der Grient ◽  
Eberhard Schatz ◽  
Daniela K. van Santen ◽  
Anders Boyd ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Linkage To Care ◽  
Credible Interval ◽  
Case Finding ◽  
Hcv Rna ◽  
People Who Use Drugs ◽  
Posterior Odds ◽  
Homeless Services ◽  
Comprehensive Service

People who inject drugs (PWID) are disproportionately affected by hepatitis C virus (HCV) infections and are frequently homeless. To improve HCV case finding in these individuals, we examined the feasibility of rapid HCV RNA testing in homeless services in Amsterdam. In 2020, we provided a comprehensive service to homeless facilities, which included workshops on HCV for personnel, a “hepatitis ambassador” at each facility, a rapid, onsite HCV RNA fingerstick test service, and assistance with linkage to care. Risk factors for HCV RNA-positive status were examined using Bayesian logistic regression. Of the 152 participants enrolled, 150 (87% men; median age: 47 years) accepted rapid HCV testing. Seven tested HCV RNA positive (4.7%, 95%CrI = 1.31–8.09; 7/150). Of these, five (71%) were linked to care, of whom four (57%, 4/7) initiated treatment and one (14%, 1/7) delayed treatment due to a drug–drug interaction. Of these four people, two completed treatment (50%), of whom one (25%) achieved sustained virologic response after 12 weeks. HCV RNA-positive individuals were more likely to originate from Eastern Europe (posterior-odds ratio (OR) = 3.59 (95% credible interval (CrI) = 1.27–10.04)) and to inject drugs (ever: posterior-OR = 3.89 (95% CrI = 1.37–11.09); recent: posterior-OR = 3.94 (95% CrI = 1.29–11.71)). We identified HCV RNA-positive individuals and linkage to care was relatively high. Screening in homeless services with rapid testing is feasible and could improve HCV case finding for PWID who do not regularly attend primary care or other harm reduction services for people who use drugs.

The 8th Canadian Symposium on Hepatitis C virus: “Improving diagnosis and linkage to care”

2020 ◽  
Vol 3 (1) ◽  
pp. 3-14
Author(s):  
Sophie E Cousineau ◽  
Aysegul Erman ◽  
Lewis Liu ◽  
Sahar Saeed ◽  
Lorraine Fradette ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Linkage To Care
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