No demonstrable ultrastructural adaptation of the human myotendinous junction to immobilization or 4 weeks of heavy resistance training

2021 ◽  
Author(s):  
A.B. Knudsen ◽  
A.L. Mackey ◽  
J.R. Jakobsen ◽  
M.R. Krogsgaard
Keyword(s):  
Resistance Training ◽  
Myotendinous Junction ◽  
Heavy Resistance Training

Composition and adaptation of human myotendinous junction and neighboring muscle fibers to heavy resistance training

2016 ◽  
Vol 27 (12) ◽  
pp. 1547-1559 ◽  
Author(s):  
J. R. Jakobsen ◽  
A. L. Mackey ◽  
A. B. Knudsen ◽  
M. Koch ◽  
M. Kjaer ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Fibers ◽  
Myotendinous Junction ◽  
Heavy Resistance Training

scholarly journals Myotendinous junction adaptations to ladder-based resistance training: identification of a new telocyte niche

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jurandyr Pimentel Neto ◽  
Lara Caetano Rocha ◽  
Gabriela Klein Barbosa ◽  
Carolina dos Santos Jacob ◽  
Walter Krause Neto ◽  
...  
Keyword(s):  
Resistance Training ◽  
Myotendinous Junction

Effects of heavy-resistance training on hormonal response patterns in younger vs. older men

1999 ◽  
Vol 87 (3) ◽  
pp. 982-992 ◽  
Author(s):  
William J. Kraemer ◽  
Keijo Häkkinen ◽  
Robert U. Newton ◽  
Bradley C. Nindl ◽  
Jeff S. Volek ◽  
...  
Keyword(s):  
Resistance Training ◽  
Training Program ◽  
Free Testosterone ◽  
Older Men ◽  
Total Testosterone ◽  
Igf I ◽  
Before And After ◽  
Igf Binding ◽  
Heavy Resistance Training ◽  
Igf Binding Protein

To examine the adaptations of the endocrine system to heavy-resistance training in younger vs. older men, two groups of men (30 and 62 yr old) participated in a 10-wk periodized strength-power training program. Blood was obtained before, immediately after, and 5, 15, and 30 min after exercise at rest before and after training and at rest at −3, 0, 6, and 10 wk for analysis of total testosterone, free testosterone, cortisol, growth hormone, lactate, and ACTH analysis. Resting values for insulin-like growth factor (IGF)-I and IGF-binding protein-3 were determined before and after training. A heavy-resistance exercise test was used to evaluate the exercise-induced responses (4 sets of 10-repetition maximum squats with 90 s of rest between sets). Squat strength and thigh muscle cross-sectional area increased for both groups. The younger group demonstrated higher total and free testosterone and IGF-I than the older men, training-induced increases in free testosterone at rest and with exercise, and increases in resting IGF-binding protein-3. With training the older group demonstrated a significant increase in total testosterone in response to exercise stress along with significant decreases in resting cortisol. These data indicate that older men do respond with an enhanced hormonal profile in the early phase of a resistance training program, but the response is different from that of younger men.

The Time Course for Elevated Muscle Protein Synthesis Following Heavy Resistance Exercise

1995 ◽  
Vol 20 (4) ◽  
pp. 480-486 ◽  
Author(s):  
J. Duncan MacDougall ◽  
Martin J. Gibala ◽  
Mark A. Tarnopolsky ◽  
Jay R. MacDonald ◽  
Stephen A. Interisano ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Training ◽  
Time Course ◽  
Biceps Brachii ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Training Session ◽  
Constant Infusion ◽  
Heavy Resistance Training

It has been shown that muscle protein synthetic rate (MPS) is elevated in humans by 50% at 4 hrs following a bout of heavy resistance training, and by 109% at 24 hrs following training. This study further examined the time course for elevated muscle protein synthesis by examining its rate at 36 hrs following a training session. Six healthy young men performed 12 sets of 6- to 12-RM elbow flexion exercises with one arm while the opposite arm served as a control. MPS was calculated from the in vivo rate of incorporation of L-[1,2−13C2] leucine into biceps brachii of both arms using the primed constant infusion technique over 11 hrs. At an average time of 36 hrs postexercise, MPS in the exercised arm had returned to within 14% of the control arm value, the difference being nonsignificant. It is concluded that following a bout of heavy resistance training, MPS increases rapidly, is more than double at 24 hrs, and thereafter declines rapidly so that at 36 hrs it has almost returned to baseline. Key words: L-[−13C] leucine, muscle hypertrophy, training frequency, mass spectrometry

Effects of an Alleged Myostatin-Binding Supplement and Heavy Resistance Training on Serum Myostatin, Muscle Strength and Mass, and Body Composition

2004 ◽  
Vol 14 (4) ◽  
pp. 461-472 ◽  
Author(s):  
Darryn S. Willoughby
Keyword(s):  
Body Composition ◽  
Resistance Training ◽  
Muscle Strength ◽  
Serum Levels ◽  
Fat Free Mass ◽  
Double Blind ◽  
Total Body Mass ◽  
Before And After ◽  
Heavy Resistance Training ◽  
Total Body

This study examined 12 wk of resistance training and cystoseim canariensis supplementation on serum levels of myostatin and follistatin-like related gene (FLRG) and muscle strength and body composition. Twenty-two untrained males were randomly assigned to a placebo (PLC) or myostatin binder (MYO) group in a double-blind fashion. Blood was obtained before and after 6 and 12 wk of training. PLC and MYO trained thrice weekly using 3 sets of 6 to 8 repetitions at 85% to 90% 1 repetition maximum. MYO ingested 1200 mg/d of cystoseim canariensis. Data were analyzed with 2-way ANOVA. After training, total body mass, fat-free mass, muscle strength, thigh volume/mass, and serum myostatin and FLRG increased for both groups (P < 0.05); however, there were no differences between groups (P > 0.05). Twelve wk of heavy resistance training and 1200 mg/d of cystoseim canariensis supplementation appears ineffective at inhibiting serum myostatin and increasing muscle strength and mass or decreasing fat mass.

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