scholarly journals Intra‐arterial blood pressure traits during and after heavy resistance exercise in healthy males

2019 ◽  
Vol 2 (6) ◽  
pp. 325-333
Author(s):  
Kim Arne Heitmann ◽  
Håvard Dalen ◽  
Guri Holmen Gundersen ◽  
Rolf Petter Ingvaldsen ◽  
Boye Welde
Keyword(s):  
Blood Pressure ◽  
Resistance Exercise ◽  
Arterial Blood Pressure ◽  
Arterial Blood ◽  
Heavy Resistance Exercise ◽  
Healthy Males

Strength training reduces arterial blood pressure but not sympathetic neural activity in young normotensive subjects

2003 ◽  
Vol 94 (6) ◽  
pp. 2212-2216 ◽  
Author(s):  
Jason R. Carter ◽  
Chester A. Ray ◽  
Emily M. Downs ◽  
William H. Cooke
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Resistance Training ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Arterial Blood Pressure ◽  
Whole Body ◽  
Arterial Blood ◽  
Blood Pressures ◽  
Body Resistance

The effects of resistance training on arterial blood pressure and muscle sympathetic nerve activity (MSNA) at rest have not been established. Although endurance training is commonly recommended to lower arterial blood pressure, it is not known whether similar adaptations occur with resistance training. Therefore, we tested the hypothesis that whole body resistance training reduces arterial blood pressure at rest, with concomitant reductions in MSNA. Twelve young [21 ± 0.3 (SE) yr] subjects underwent a program of whole body resistance training 3 days/wk for 8 wk. Resting arterial blood pressure ( n = 12; automated sphygmomanometer) and MSNA ( n = 8; peroneal nerve microneurography) were measured during a 5-min period of supine rest before and after exercise training. Thirteen additional young (21 ± 0.8 yr) subjects served as controls. Resistance training significantly increased one-repetition maximum values in all trained muscle groups ( P < 0.001), and it significantly decreased systolic (130 ± 3 to 121 ± 2 mmHg; P = 0.01), diastolic (69 ± 3 to 61 ± 2 mmHg; P = 0.04), and mean (89 ± 2 to 81 ± 2 mmHg; P = 0.01) arterial blood pressures at rest. Resistance training did not affect MSNA or heart rate. Arterial blood pressures and MSNA were unchanged, but heart rate increased after 8 wk of relative inactivity for subjects in the control group (61 ± 2 to 67 ± 3 beats/min; P = 0.01). These results indicate that whole body resistance exercise training might decrease the risk for development of cardiovascular disease by lowering arterial blood pressure but that reductions of pressure are not coupled to resistance exercise-induced decreases of sympathetic tone.

Naloxone enhances the increase in plasma growth hormone induced by α2-adrenergic stimulation in healthy males

1987 ◽  
Vol 114 (2) ◽  
pp. 308-313 ◽  
Author(s):  
Margareta Bramnert ◽  
Bernt Hökfelt
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Adrenergic Stimulation ◽  
Arterial Blood ◽  
Normotensive Subjects ◽  
Pre Treatment ◽  
Plasma Gh ◽  
Single Blind ◽  
Healthy Males

Abstract. There is evidence that the α2-adrenergic agonist clonidine interacts with the opioid system. In the present investigations, the effect of naloxone on the increase in plasma GH induced by clonidine and the more specific α2-agonist guanfacine was studied in man. In a single-blind study, five healthy males received in randomized order either the preservatives in the naloxone preparation (control) or naloxone at two different doses (10 or 100 μg/kg) followed by an infusion of either diluted preservatives or naloxone (5 or 50 μg · kg−1 · h−1, respectively). Fifteen min after the bolus dose, clonidine (3 μg/kg) or guanfacine (15 μg/kg) was infused over 10 min in a single-blind order. Both clonidine and guanfacine induced an increase in plasma GH (P < 0.05), Pre-treatment with naloxone at the higher dosage resulted in an enhanced (P < 0.05) GH response to clonidine and guanfacine, respectively, whereas the lower dosage of naloxone was without effect. The increase in plasma GH did not correlate with basal mean arterial blood pressure, nor with the changes in mean arterial blood pressure induced by clonidine or guanfacine. These results indicate that the increase in plasma GH induced by α2-adrenergic stimulation in normotensive subjects involves opioid receptors with moderate sensitivity to naloxone.

scholarly journals Intra-arterial blood pressure response in hypertensive subjects during low- and high-intensity resistance exercise

Clinics ◽  
2010 ◽  
Vol 65 (3) ◽  
pp. 271-277 ◽  
Author(s):  
Sandra de Souza Nery ◽  
Ricardo Saraceni Gomides ◽  
Giovanio Vieira da Silva ◽  
Claudia Lucia de Moraes Forjaz ◽  
Décio Mion Jr ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Resistance Exercise ◽  
Arterial Blood Pressure ◽  
High Intensity ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Arterial Blood

Cardiovascular Effects of Micromeria graeca (L.) Benth. ex Rchb in Normotensive and Hypertensive Rats

2020 ◽  
Vol 20 (8) ◽  
pp. 1253-1261
Author(s):  
Mourad Akdad ◽  
Mohamed Eddouks
Keyword(s):  
Blood Pressure ◽  
Cardiovascular System ◽  
Arterial Blood Pressure ◽  
Antihypertensive Activity ◽  
Computer Assisted ◽  
Hypertensive Rats ◽  
Vasorelaxant Effect ◽  
Arterial Blood

Aims: The present study was performed in order to analyze the antihypertensive activity of Micromeria graeca (L.) Benth. ex Rchb. Background: Micromeria graeca (L.) Benth. ex Rchb is an aromatic and medicinal plant belonging to the Lamiaceae family. This herb is used to treat various pathologies such as cardiovascular disorders. Meanwhile, its pharmacological effects on the cardiovascular system have not been studied. Objective: The present study aimed to evaluate the effect of aqueous extract of aerial parts of Micromeria graeca (AEMG) on the cardiovascular system in normotensive and hypertensive rats. Methods: In this study, the cardiovascular effect of AEMG was evaluated using in vivo and in vitro investigations. In order to assess the acute effect of AEMG on the cardiovascular system, anesthetized L-NAME-hypertensive and normotensive rats received AEMG (100 mg/kg) orally and arterial blood pressure parameters were monitored during six hours. In the sub-chronic study, rats were orally treated for one week, followed by blood pressure assessment during one week of treatment. Blood pressure was measured using a tail-cuff and a computer-assisted monitoring device. In the second experiment, isolated rat aortic ring pre-contracted with Epinephrine (EP) or KCl was used to assess the vasorelaxant effect of AEMG. Results: Oral administration of AEMG (100 mg/kg) provoked a decrease of arterial blood pressure parameters in hypertensive rats. In addition, AEMG induced a vasorelaxant effect in thoracic aortic rings pre-contracted with EP (10 μM) or KCl (80 mM). This effect was attenuated in the presence of propranolol and methylene blue. While in the presence of glibenclamide, L-NAME, nifedipine or Indomethacin, the vasorelaxant effect was not affected. Conclusion: This study showed that Micromeria graeca possesses a potent antihypertensive effect and relaxes the vascular smooth muscle through β-adrenergic and cGMP pathways.

THE REGULATION OF ARTERIAL BLOOD PRESSURE

1946 ◽  
Vol 146 (3) ◽  
pp. 410-421 ◽  
Author(s):  
J. P. Holt ◽  
W. J. Rashkind ◽  
R. Bernstein ◽  
J. C. Greisen
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Arterial Blood
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