Methylisothiazolinone may induce cell death and inflammatory response through DNA damage in human liver epithelium cells

2017 ◽  
Vol 33 (2) ◽  
pp. 156-166 ◽  
Author(s):  
Eun-Jung Park ◽  
Sanghwa Kim ◽  
Jaerak Chang
Keyword(s):  
Dna Damage ◽  
Cell Death ◽  
Inflammatory Response ◽  
Human Liver ◽  
Induce Cell Death ◽  
Epithelium Cells

scholarly journals Novel Nitrobenzazolo[3,2-a]quinolinium Salts Induce Cell Death through a Mechanism Involving DNA Damage, Cell Cycle Changes, and Mitochondrial Permeabilization

2013 ◽  
Vol 02 (02) ◽  
pp. 13-22 ◽  
Author(s):  
Christian Vélez ◽  
Osvaldo Cox ◽  
Carlos A. Rosado-Berrios ◽  
Dennise Molina ◽  
Luz Arroyo ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Dna Damage ◽  
Cell Death ◽  
Induce Cell Death ◽  
Damage Cell ◽  
Mitochondrial Permeabilization ◽  
Quinolinium Salts

An oxo(corrolato)chromium(V) complex selectively kills cancer cells by inducing DNA damage

2021 ◽  
Author(s):  
Nitika Pradhan ◽  
Antara Garai ◽  
Bratati Patra ◽  
Sanjib Kar ◽  
Prasanta K. Maiti
Keyword(s):  
Dna Damage ◽  
Cell Death ◽  
Cancer Cells ◽  
Leukemia Cells ◽  
Induce Cell Death

An oxo(corrolato)chromium(V) complex selectively kills leukemia cells. However, this complex did not induce cell death in primary non-cancer cells. It has been observed that oxo(corrolato)chromium(V) complex induced cell death is...

scholarly journals Effects of Cisplatin in Neuroblastoma Rat Cells: Damage to Cellular Organelles

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Giada Santin ◽  
Luigi Scietti ◽  
Paola Veneroni ◽  
Sergio Barni ◽  
Graziella Bernocchi ◽  
...  
Keyword(s):  
Dna Damage ◽  
Cell Death ◽  
Golgi Apparatus ◽  
Cytotoxic Effect ◽  
Induce Cell Death ◽  
Functional Changes ◽  
Apoptotic Process ◽  
Chemotherapy Agent ◽  
Cellular Organelles

Cisplatin (cisPt) is a chemotherapy agent used as a treatment for several types of cancer. The main cytotoxic effect of cisplatin is generally accepted to be DNA damage. Recently, the mechanism by which cisPt generates the cascade of events involved in the apoptotic process has been demonstrated. In particular it has been shown that some organelles are cisPt target and are involved in cell death. This paper aims to describe the morphological and functional changes of the Golgi apparatus and lysosomes during apoptosis induced in neuronal rat cells (B50) by cisplatin. The results obtained show that the cellular organelles are the target of cisPt, so their damage can induce cell death.

scholarly journals Thyroid hormones derivatives reduce proliferation and induce cell death and DNA damage in ovarian cancer

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Elena Shinderman-Maman ◽  
Keren Cohen ◽  
Dotan Moskovich ◽  
Aleck Hercbergs ◽  
Haim Werner ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Dna Damage ◽  
Cell Death ◽  
Thyroid Hormones ◽  
Induce Cell Death

Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

2017 ◽  
Author(s):  
Ellen Sletten ◽  
Rachael A. Day ◽  
Daniel A. Estabrook ◽  
Jessica K. Logan
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Induce Cell Death ◽  
Perfluorocarbon Nanoemulsions

<p>Photodynamic therapy (PDT) requires photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT. </p>

Sign in / Sign up

Export Citation Format

Share Document