Reproductive toxicity and histopathological changes induced by lambda-cyhalothrin in male mice

2012 ◽  
Vol 29 (7) ◽  
pp. 750-762 ◽  
Author(s):  
Ali S. Al-Sarar ◽  
Yasser Abobakr ◽  
Alaa E. Bayoumi ◽  
Hamdy I. Hussein ◽  
Mousa Al-Ghothemi
Keyword(s):  
Reproductive Toxicity ◽  
Male Mice ◽  
Histopathological Changes ◽  
Lambda Cyhalothrin

scholarly journals Study of the protective effect of Nigella sativa against Cimetidine induced reproductive toxicity in male mice

2010 ◽  
Vol 9 (1) ◽  
pp. 55 ◽  
Author(s):  
K. G. Ch. Al-Nailey
Keyword(s):  
Nigella Sativa ◽  
Aqueous Suspension ◽  
Reproductive Toxicity ◽  
Reproductive Organs ◽  
Seminiferous Tubules ◽  
Control Group ◽  
Male Mice ◽  
Histopathological Changes ◽  
Once Daily ◽  
Long Term Treatment

The present study was designed to investigate some histopathological changes produced by cimetidine on male reproductive organs (testes & epididymis) in mice and extended to examine where there using of an aqueous suspension of powdered Nigella sativa seeds have the ability to reduce this toxicity. Forty male mice were divided into 4 groups. The first group received 25 mg/kg B.W. of cimetidine orally once daily. The second group drenched aqueous suspension of Nigella sativa at a dose of 1000mg/kg B.W. and then received cimetidine. While the third group drenched Nigella sativa aqueous suspension once daily, while the fourth group (control group) received normal saline only and the study was continued for (76 days). Animals which were treated with cimetidine only along the period of the experiment showed severe pathological changes, particularly in testes and epididymis, whereas oral administration of the aqueous suspension of Nigella seeds aqueous suspension significantly reduced these changes which reflected by an obvious increment of spermatogonia and reducing the damage of seminiferous tubules. The protective activity of Nigella sativa has been resumed via diminishing the reproductive histopathological changes associated with long-term treatment with cimetidine.

The flavonoid chrysin protects against zearalenone induced reproductive toxicity in male mice

Toxicon ◽  
2019 ◽  
Vol 165 ◽  
pp. 13-21 ◽  
Author(s):  
Lucian Del Fabbro ◽  
Cristiano Ricardo Jesse ◽  
Marcelo Gomes de Gomes ◽  
Carlos Borges Filho ◽  
Franciele Donato ◽  
...  
Keyword(s):  
Reproductive Toxicity ◽  
Male Mice

Effect of a beta-cypermethrin and emamectin benzoate pesticide mixture on reproductive toxicity in male mice in a greenhouse environment

2019 ◽  
Vol 30 (2) ◽  
pp. 100-106 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Chang Kong ◽  
Huimin Chi ◽  
Junxia Li ◽  
Jie Xing ◽  
...  
Keyword(s):  
Reproductive Toxicity ◽  
Male Mice ◽  
Emamectin Benzoate ◽  
Pesticide Mixture

scholarly journals Biochemical and histopathological changes in the kidney and adrenal gland of rats following repeated exposure to lambda-cyhalothrin

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Hassina Khaldoun Oularbi
Keyword(s):  
Adrenal Glands ◽  
Rat Plasma ◽  
Pyrethroid Insecticide ◽  
Control Group ◽  
Type Ii ◽  
Histopathological Changes ◽  
Plasma Urea ◽  
Lambda Cyhalothrin ◽  
Histopathological Studies ◽  
Group 1

Lambda-cyhalothrin (LCT) is a type II pyrethroid insecticide widely used in pest management. This study was undertaken to evaluate the toxic effects of LCT on the kidneys and adrenal glands of rats after subacute exposure. Twenty-eight 6-week-old male albino <em>Rattus norvegicus</em> rats were randomly assigned to four groups. Group 1 was the control group, which received distilled water. The experimental groups 2, 3 and 4 received 20.4, 30.6 and 61.2 mg/kg body weight, respectively, of LCT, administered orally over 28 days. The effects of the insecticide on various biochemical parameters were evaluated at 14 and 28 days. Histopathological studies were carried out in the kidneys and adrenal glands at the end of the experiment. Lambda-cyhalothrin, as a pyrethroid insecticide, induced significant increases (P≤0.05) in plasma urea, creatinine, uric acid and glucose concentrations, and alanine aminotransferase and aspartate aminotransferase activities after 14 and 28 days. In the rat plasma samples after 28 days, residual concentrations of LCT 1R, cis,

scholarly journals SF-1 mediates reproductive toxicity induced by Cerium oxide nanoparticles in male mice

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Fenju Qin ◽  
Tao Shen ◽  
Jinlin Li ◽  
Junchao Qian ◽  
Jie Zhang ◽  
...  
Keyword(s):  
Cerium Oxide ◽  
Reproductive Toxicity ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Male Mice

Assessment of reproductive toxicity of orally administered technical dimethoate in male mice

2007 ◽  
Vol 23 (2) ◽  
pp. 232-238 ◽  
Author(s):  
Amina T. Farag ◽  
Ahmed F. El-Aswad ◽  
Nasra A. Shaaban
Keyword(s):  
Reproductive Toxicity ◽  
Male Mice

The resin monomer triethylene glycol dimethacrylate exhibits reproductive toxicity in male mice

2005 ◽  
Vol 17 (4) ◽  
pp. 401 ◽  
Author(s):  
Homa Darmani ◽  
Ahmad S. Al-Hiyasat
Keyword(s):  
Reproductive Toxicity ◽  
Triethylene Glycol ◽  
Testis Weight ◽  
Male Mice ◽  
Triethylene Glycol Dimethacrylate ◽  
Sperm Counts ◽  
Untreated Female ◽  
Preputial Glands ◽  
Sexually Mature ◽  
Triethyleneglycol Dimethacrylate

The present study evaluated the effect of triethyleneglycol dimethacrylate (TEGDMA) on mouse fertility. Adult male mice were administered TEGDMA (0, 25 and 100 μg kg–1) intragastrically daily for 28 days and then allowed to mate for 10 days with sexually mature untreated female mice; fertility was assessed after a further 10 days. Females mated by males that had been treated with TEGDMA had a significant reduction in pregnancy rate, as well as a significant increase in the total number of resorptions as a percentage of the total number of implantations. Furthermore, the number of animals in which resorption occcurred was increased significantly. Males treated with TEGDMA exhibited a significant reduction in bodyweight, testis weight and the weight of the seminal vesicles and preputial glands. Testicular and epididymal sperm counts, as well as the efficiency of sperm production, were also significantly reduced in TEGDMA-treated males. The results suggest that TEGDMA has adverse effects on the fertility and reproductive system of male mice.

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