Sodium arsenite induced reactive oxygen species generation, nuclear factor (erythroid-2 related) factor 2 activation, heme oxygenase-1 expression, and glutathione elevation in Chang human hepatocytes

2011 ◽  
Vol 28 (7) ◽  
pp. 401-410 ◽  
Author(s):  
Bing Li ◽  
Xin Li ◽  
Bo Zhu ◽  
Xinyu Zhang ◽  
Yi Wang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Heme Oxygenase ◽  
Sodium Arsenite ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Human Hepatocytes ◽  
Heme Oxygenase 1 ◽  
Related Factor ◽  
Nuclear Factor ◽  
Oxygen Species

scholarly journals P4 Aldosterone-Induced Vascular Dysfunction by Decreasing Nuclear Factor Erythroid 2–Related Factor 2 Activity and Increasing Reactive Oxygen Species Generation

2020 ◽  
Vol 25 (Supplement 1) ◽  
pp. S46
Author(s):  
Daniel Rodrigues ◽  
Tiago Januário da Costa ◽  
Rafael Menezes da Costa ◽  
Rita de Cássia Aleixo Tostes Passaglia
Keyword(s):  
Reactive Oxygen Species ◽  
Vascular Dysfunction ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Related Factor ◽  
Nuclear Factor ◽  
Oxygen Species

Trilobatin Protects Cardiomyocytes from Hypoxia/ Reperfusion Injury by Regulating the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway

2020 ◽  
Vol 19 (2) ◽  
pp. 133-138
Author(s):  
Wenyu Chen ◽  
Hui He
Keyword(s):  
Heme Oxygenase ◽  
Molecular Mechanisms ◽  
Heme Oxygenase 1 ◽  
Related Factor ◽  
Cellular Injury ◽  
Nuclear Factor ◽  
Oxygen Species ◽  
H9c2 Cells ◽  
Natural Plant ◽  
Induced Changes

Trilobatin is a natural plant-derived glycosylated flavonoid that has been shown to exhibit multiple beneficial pharmacologic activities including protection of heart against H/R-induced cardiomyocyte injury. However, the molecular mechanisms underlying protection from H/R-induced cardiomyocyte injury remain unknown. Using H9C2 cells as a model, we examined the effect of trilobatin on H/R-induced cellular injury, apoptosis, and generation of reactive oxygen species. The results showed that trilobatin protected H9C2 cells not only from cell death and apoptosis, but also counteracted H/R-induced changes in malondialdehyde, superoxide dismutase, glutathione, and glutathione peroxidase. The evaluation of the mechanism underlying the effect of trilobatin on protection from H/R-induced cellular injury suggested changes in the regulation of nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway.

Cytotoxic effects of metal protoporphyrins in glioblastoma cells: Roles of albumin, reactive oxygen species, and heme oxygenase-1

2008 ◽  
Vol 177 (2) ◽  
pp. 97-107 ◽  
Author(s):  
Jyh-Ming Chow ◽  
Guan-Cheng Huang ◽  
Hui-Yi Lin ◽  
Shing-Chuan Shen ◽  
Liang-Yo Yang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Heme Oxygenase ◽  
Reactive Oxygen ◽  
Heme Oxygenase 1 ◽  
Oxygen Species ◽  
Glioblastoma Cells ◽  
Cytotoxic Effects

scholarly journals 15-Deoxy-Δ12,14-prostaglandin J2Induces Heme Oxygenase-1 Gene Expression in a Reactive Oxygen Species-dependent Manner in Human Lymphocytes

2004 ◽  
Vol 279 (21) ◽  
pp. 21929-21937 ◽  
Author(s):  
Moisés Álvarez-Maqueda ◽  
Rajaa El Bekay ◽  
Gonzalo Alba ◽  
Javier Monteseirín ◽  
Pedro Chacón ◽  
...  
Keyword(s):  
Gene Expression ◽  
Reactive Oxygen Species ◽  
Heme Oxygenase ◽  
Human Lymphocytes ◽  
Reactive Oxygen ◽  
Heme Oxygenase 1 ◽  
Dependent Manner ◽  
Oxygen Species
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