Injectable hydrogels for tendon and ligament tissue engineering

2020 ◽  
Author(s):  
Richun Liu ◽  
Shichen Zhang ◽  
Xiao Chen
Keyword(s):  
Tissue Engineering ◽  
Injectable Hydrogels ◽  
Ligament Tissue Engineering

Mechano growth factor-C24E, a potential promoting biochemical factor for ligament tissue engineering

2016 ◽  
Vol 105 ◽  
pp. 249-263 ◽  
Author(s):  
Yang Song ◽  
Can Yu ◽  
Chunli Wang ◽  
Xingshuang Ma ◽  
Kang Xu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Growth Factor ◽  
Mechano Growth Factor ◽  
Biochemical Factor ◽  
Ligament Tissue Engineering

scholarly journals Significance of Crosslinking Approaches in the Development of Next Generation Hydrogels for Corneal Tissue Engineering

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 319
Author(s):  
Promita Bhattacharjee ◽  
Mark Ahearne
Keyword(s):  
Tissue Engineering ◽  
Chemical Structure ◽  
Biochemical Properties ◽  
Corneal Tissue ◽  
Future Prospects ◽  
Chemical Additives ◽  
Injectable Hydrogels ◽  
Corneal Regeneration ◽  
Key Factor ◽  
Fuchs Endothelial Dystrophy

Medical conditions such as trachoma, keratoconus and Fuchs endothelial dystrophy can damage the cornea, leading to visual deterioration and blindness and necessitating a cornea transplant. Due to the shortage of donor corneas, hydrogels have been investigated as potential corneal replacements. A key factor that influences the physical and biochemical properties of these hydrogels is how they are crosslinked. In this paper, an overview is provided of different crosslinking techniques and crosslinking chemical additives that have been applied to hydrogels for the purposes of corneal tissue engineering, drug delivery or corneal repair. Factors that influence the success of a crosslinker are considered that include material composition, dosage, fabrication method, immunogenicity and toxicity. Different crosslinking techniques that have been used to develop injectable hydrogels for corneal regeneration are summarized. The limitations and future prospects of crosslinking strategies for use in corneal tissue engineering are discussed. It is demonstrated that the choice of crosslinking technique has a significant influence on the biocompatibility, mechanical properties and chemical structure of hydrogels that may be suitable for corneal tissue engineering and regenerative applications.

Feature

2011 ◽  
Vol 15 (01) ◽  
pp. 13-25 ◽  
Keyword(s):  
Tissue Engineering ◽  
Asia Pacific ◽  
Ligament Tissue Engineering

Tendon & Ligament Tissue Engineering: How to do it and how to know you've done it right? Realizing the Promise of Asia-Pacific: The Strategic Shift from Outsourcing to Innovation. FEI: Opening Worlds Within Our World.

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