Bioactive glass containing 90% SiO 2 in hard tissue engineering: An in vitro and in vivo characterization study

2019 ◽  
Vol 13 (9) ◽  
pp. 1651-1663
Author(s):  
Luiz Felipe Cardoso Lehman ◽  
Mariana Saturnino Noronha ◽  
Ivana Márcia Alves Diniz ◽  
Rosangela Maria Ferreira Costa e Silva ◽  
Ângela Leão Andrade ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Hard Tissue ◽  
Characterization Study ◽  
In Vivo Characterization ◽  
Hard Tissue Engineering

Preparation and performance evaluation of electrospun poly(3-hydroxybutyrate) composite scaffolds as a potential hard tissue engineering application

2019 ◽  
Vol 34 (4-5) ◽  
pp. 386-400 ◽  
Author(s):  
Moein Zarei ◽  
Nader Tanideh ◽  
Shahrokh Zare ◽  
Fatemeh Sari Aslani ◽  
Omid Koohi-Hosseinabadi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Carbon Nanotube ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Hydroxyapatite Nanoparticles ◽  
Hard Tissue ◽  
Composite Scaffolds ◽  
Tissue Reactions ◽  
Hard Tissue Engineering

In the present study, poly(3-hydroxybutyrate)-based composite scaffolds were prepared with multi-walled carbon nanotubes and hydroxyapatite nanoparticles for hard tissue engineering applications by electrospinning. All the prepared scaffolds showed connective porous structure, which were suitable for cell proliferation and migration. The mechanical properties of the poly(3-hydroxybutyrate) scaffold were improved by 0.5% of carbon nanotube addition, whereas the addition of hydroxyapatite nanoparticles up to 10% had an insignificant effect in tensile strength. However, scanning electron microscopy and MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay results suggested that the mesenchymal stem cells attachment and their metabolic activities on the surface of the poly(3-hydroxybutyrate) scaffolds with hydroxyapatite were enhanced compared to poly(3-hydroxybutyrate) scaffolds. In addition, after 6 weeks of in vivo biocompatibility results in a model of rat indicated better tissue reactions for the scaffolds that contained hydroxyapatite. Overall, poly(3-hydroxybutyrate) composite scaffolds with 10% hydroxyapatite and 0.5% carbon nanotube showed optimal performances for the potential scaffold for hard tissue engineering application.

Evaluation of 3D nano–macro porous bioactive glass scaffold for hard tissue engineering

2011 ◽  
Vol 22 (5) ◽  
pp. 1195-1203 ◽  
Author(s):  
S. Wang ◽  
M. M. Falk ◽  
A. Rashad ◽  
M. M. Saad ◽  
A. C. Marques ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Hard Tissue ◽  
Hard Tissue Engineering

scholarly journals In vitro and in vivo Biocompatibility of Alginate Dialdehyde/Gelatin Hydrogels with and without Nanoscaled Bioactive Glass for Bone Tissue Engineering Applications

Materials ◽  
2014 ◽  
Vol 7 (3) ◽  
pp. 1957-1974 ◽  
Author(s):  
Ulrike Rottensteiner ◽  
Bapi Sarker ◽  
Dominik Heusinger ◽  
Diana Dafinova ◽  
Subha Rath ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Engineering Applications

Synthesis, characterization and cytocompatibility of spherical bioactive glass nanoparticles for potential hard tissue engineering applications

2013 ◽  
Vol 8 (2) ◽  
pp. 025011 ◽  
Author(s):  
Agda Aline Rocha de Oliveira ◽  
Dickson Alves de Souza ◽  
Luisa Lima Silveira Dias ◽  
Sandhra Maria de Carvalho ◽  
Herman Sander Mansur ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Hard Tissue ◽  
Engineering Applications ◽  
Hard Tissue Engineering
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