A promising therapeutic option for diabetic bladder dysfunction: Adipose tissue‐derived stem cells pretreated by defocused low‐energy shock wave

2019 ◽  
Author(s):  
Haiyang Zhang ◽  
Yong Zhao ◽  
Muwen Wang ◽  
Wei Song ◽  
Peng Sun ◽  
...  
Keyword(s):  
Shock Wave ◽  
Stem Cells ◽  
Adipose Tissue ◽  
Bladder Dysfunction ◽  
Therapeutic Option ◽  
Low Energy ◽  
Diabetic Bladder

Endogenous Stem Cells Were Recruited by Defocused Low-Energy Shock Wave in Treating Diabetic Bladder Dysfunction

2016 ◽  
Vol 13 (2) ◽  
pp. 287-298 ◽  
Author(s):  
Yang Jin ◽  
Lina Xu ◽  
Yong Zhao ◽  
Muwen Wang ◽  
Xunbo Jin ◽  
...  
Keyword(s):  
Shock Wave ◽  
Stem Cells ◽  
Bladder Dysfunction ◽  
Low Energy ◽  
Diabetic Bladder

Defocused low-energy shock wave activates adipose tissue-derived stem cells in vitro via multiple signaling pathways

Cytotherapy ◽  
2016 ◽  
Vol 18 (12) ◽  
pp. 1503-1514 ◽  
Author(s):  
Lina Xu ◽  
Yong Zhao ◽  
Muwen Wang ◽  
Wei Song ◽  
Bo Li ◽  
...  
Keyword(s):  
Shock Wave ◽  
Stem Cells ◽  
Adipose Tissue ◽  
Signaling Pathways ◽  
Low Energy ◽  
Multiple Signaling

scholarly journals Adipose Tissue-Derived Stem Cells Ameliorate Diabetic Bladder Dysfunction in a Type II Diabetic Rat Model

2012 ◽  
Vol 21 (9) ◽  
pp. 1391-1400 ◽  
Author(s):  
Haiyang Zhang ◽  
Xuefeng Qiu ◽  
Alan W. Shindel ◽  
Hongxiu Ning ◽  
Ludovic Ferretti ◽  
...  
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Rat Model ◽  
Bladder Dysfunction ◽  
Diabetic Rat ◽  
Type Ii ◽  
Diabetic Bladder ◽  
Diabetic Rat Model

scholarly journals Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Enrique Calvo ◽  
Noelia Keiran ◽  
Catalina Núñez-Roa ◽  
Elsa Maymó-Masip ◽  
Miriam Ejarque ◽  
...  
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Therapeutic Option ◽  
Metabolic Activation ◽  
Diet Induced Obesity ◽  
Brown Adipose ◽  
Obesity In Mice ◽  
Treatment Of Obesity ◽  
Visceral Adipose

AbstractAdipose-derived mesenchymal stem cells (ASCs) are a promising option for the treatment of obesity and its metabolic co-morbidities. Despite the recent identification of brown adipose tissue (BAT) as a potential target in the management of obesity, the use of ASCs isolated from BAT as a therapy for patients with obesity has not yet been explored. Metabolic activation of BAT has been shown to have not only thermogenic effects, but it also triggers the secretion of factors that confer protection against obesity. Herein, we isolated and characterized ASCs from the visceral adipose tissue surrounding a pheochromocytoma (IB-hASCs), a model of inducible BAT in humans. We then compared the anti-obesity properties of IB-hASCs and human ASCs isolated from visceral white adipose tissue (W-hASCs) in a murine model of diet-induced obesity. We found that both ASC therapies mitigated the metabolic abnormalities of obesity to a similar extent, including reducing weight gain and improving glucose tolerance. However, infusion of IB-hASCs was superior to W-hASCs in suppressing lipogenic and inflammatory markers, as well as preserving insulin secretion. Our findings provide evidence for the metabolic benefits of visceral ASC infusion and support further studies on IB-hASCs as a therapeutic option for obesity-related comorbidities.

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Cytotherapy ◽  
2017 ◽  
Vol 19 (9) ◽  
pp. 1079-1095 ◽  
Author(s):  
Eleni Priglinger ◽  
Christina M.A.P. Schuh ◽  
Carolin Steffenhagen ◽  
Christoph Wurzer ◽  
Julia Maier ◽  
...  
Keyword(s):  
Shock Wave ◽  
Adipose Tissue ◽  
Extracorporeal Shock Wave Therapy ◽  
Low Energy ◽  
Shock Wave Therapy ◽  
Extracorporeal Shock Wave

MP19-16 HUMAN ADIPOSE TISSUE DERIVED STEM CELLS (HADSCS) PREVENTS FIBROSIS AND BLADDER DYSFUNCTION IN A RAT MODEL OF URETHRAL STRICTURE

2015 ◽  
Vol 193 (4S) ◽  
Author(s):  
Fabio Castiglione ◽  
Maarten Albersen ◽  
Andrea Russo ◽  
Trinity J. Bivalacqua ◽  
Francesco Montorsi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Urethral Stricture ◽  
Rat Model ◽  
Bladder Dysfunction ◽  
Human Adipose Tissue
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