scholarly journals Osteogenic potential of adipogenic predifferentiated human bone marrow‐derived multipotent stromal cells for bone tissue‐engineering

Author(s):  
Adrien Moya ◽  
Nathanaël Larochette ◽  
Marianne Bourguignon ◽  
Hanane El‐Hafci ◽  
Esther Potier ◽  
...  
2002 ◽  
Vol 8 (6) ◽  
pp. 941-953 ◽  
Author(s):  
Karine Anselme ◽  
Odile Broux ◽  
Benoit Noel ◽  
Bertrand Bouxin ◽  
Gerard Bascoulergue ◽  
...  

2007 ◽  
Vol 342-343 ◽  
pp. 369-372 ◽  
Author(s):  
S.J. Heo ◽  
S.E. Kim ◽  
Yong Taek Hyun ◽  
D.H. Kim ◽  
Hyang Mi Lee ◽  
...  

This study evaluated the potential of the PCL (poly -caprolactone)/HA(Hydroxyapatite) composite materials as a scaffold for bone regeneration. For this, we fabricated scaffolds utilizing salt leaching method. The PCL/HA composite scaffolds were prepared with various HA contents (20wt%, 40wt%, 60 wt %). To ensure the potential for the scaffolds, porosity tests were conducted along with SEM observations. The porosity decreased with the increase of the contents of HA particles. The porosity of the composite with the highest contents of HA was still adoptable (~85%). In addition, the PCL/HA composite scaffolds were evaluated for their ability of osteogenic differentiation with human bone marrow stromal cell (hBMSC) in vitro. Alkaline phosphatase (ALP) activity, markers for osteoblastic differentiation, and total protein contents were evaluated in hBMSCs following 14 days of cultivation. The addition of HA particles enhanced proliferation of hBMSC during the test. Also, the differentiation ability of the cells was increased as HA particles were added. In this study, we concluded that PCL/HA composite scaffolds has great potential as a scaffold for bone tissue engineering.


2006 ◽  
Vol 0 (0) ◽  
pp. 060913044658010
Author(s):  
Fei Dai ◽  
Dongwen Shi ◽  
Weifeng He ◽  
Jun Wu ◽  
Gaoxin Luo ◽  
...  

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Alison T. Merryweather-Clarke ◽  
David Cook ◽  
Barbara Joo Lara ◽  
Peng Hua ◽  
Emmanouela Repapi ◽  
...  

2011 ◽  
Vol 26 (8) ◽  
pp. 1035-1049 ◽  
Author(s):  
Federico Foschi ◽  
Enrico Conserva ◽  
Paolo Pera ◽  
Barbara Canciani ◽  
Ranieri Cancedda ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document