Physico-chemical characterization and biological evaluation of two fibroin materials

2012 ◽  
Vol 8 (11) ◽  
pp. 874-885 ◽  
Author(s):  
Antonella Motta ◽  
Paola Segnana ◽  
Lucia Verin ◽  
Silvia La Monica ◽  
Claudia Fumarola ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Biological Evaluation ◽  
Physico Chemical

scholarly journals Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation

2016 ◽  
Vol 4 (47) ◽  
pp. 7620-7629 ◽  
Author(s):  
E. Koziolová ◽  
D. Machová ◽  
R. Pola ◽  
O. Janoušková ◽  
P. Chytil ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Controlled Drug Release ◽  
Biological Evaluation ◽  
Hpma Copolymer ◽  
Design Synthesis ◽  
Drug Conjugates ◽  
Physico Chemical ◽  
Tumor Accumulation ◽  
Polymer Drug Conjugates ◽  
Hpma Copolymer Conjugates

We describe design, synthesis, physico-chemical characterization and preliminary biological evaluation of micelle-forming polymer drug conjugates with controlled drug release intended for tumor treatment.

scholarly journals Green and Synthetic Metallic Nanoparticles - Obtaining, Characterization and Biological Evaluation in Association with Lupeol

2020 ◽  
Vol 71 (5) ◽  
pp. 299-304
Author(s):  
Flavia Bociort ◽  
Adelina Cheveresan ◽  
Razvan Dragoi ◽  
Alina Heghes ◽  
Camelia Szuhanek ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Metallic Nanoparticles ◽  
Chemical Characterization ◽  
Biological Evaluation ◽  
Colon Cancer Cells ◽  
Lemon Balm ◽  
Physico Chemical ◽  
Average Size

The field of metal nanotechnology continues to draw the attention of researchers from different areas due to the outstanding properties of nanoparticles. The main aims of this research were to obtain and to study two types of gold nanoparticles; different obtaining pathways (the chemical synthesis and the biosynthesis based on an aqueous extract of lemon balm) were involved in this research. The chemically synthesized nanoparticles were loaded with lupeol. After a preliminary physico-chemical characterization, the compounds obtained were tested in order to evaluate the effects on the viability of colon cancer cells. The formulation of these new gold nanoparticles with average size between 38 and 82 nm, with a good stability against the tendency to form agglomerations according to the Zeta potential values, was confirmed by UV-Vis spectra; the particles containing lupeol have show the best activity against the colon cancer cells.

Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation

2020 ◽  
Vol 186 ◽  
pp. 111880 ◽  
Author(s):  
Aikaterini Pagoni ◽  
Lisa Marinelli ◽  
Antonio Di Stefano ◽  
Michele Ciulla ◽  
Hasan Turkez ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Biological Evaluation ◽  
Physico Chemical

Laboratory Methods for the Physico-Chemical Characterization of Recombinant Allergens as Reference Standards

Alergologia ◽  
2020 ◽  
Vol 1 (4) ◽  
pp. 7
Author(s):  
Mariana Vieru ◽  
Florin-Dan Popescu ◽  
Laura Haidar ◽  
Carmen Bunu-Panaitescu
Keyword(s):  
Chemical Characterization ◽  
Reference Standards ◽  
Recombinant Allergens ◽  
Laboratory Methods ◽  
Physico Chemical

Mineralogical and physico-chemical characterization of a sintered feldspathic sand

2010 ◽  
Vol 35 (5) ◽  
pp. 261-267 ◽  
Author(s):  
Wissemn Gallala ◽  
Mohamed Essghaier Gaied ◽  
Borhen Kchaou
Keyword(s):  
Chemical Characterization ◽  
Physico Chemical

Physical - Chemical Issues of Cephalosporin Intercalated Nanoparticles for Life - Threatening Infections Treatment

2001 ◽  
Vol 71 (3) ◽  
pp. 342-349
Author(s):  
Lucian Eva ◽  
Letitia Doina Duceac ◽  
Liviu Stafie ◽  
Constantin Marcu ◽  
Geta Mitrea ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Advanced Characterization ◽  
Generation Cephalosporin ◽  
Fourth Generation ◽  
Exchange Method ◽  
Physico Chemical ◽  
Life Threatening ◽  
Double Hydroxide ◽  
Double Hydroxides

The fourth generation cephalosporin antibacterial agent, cefepime, was loaded into layered double hydroxides for enhancing antibiotic efficiency, reducing side effects, as well as achieving the sustained release property. The intercalation of antibiotic into the inter-gallery of ZnAl-layered double hydroxide (LDH) was carried out using ion exchange method, by this constituting a nano-sized organic-inorganic hybrid material for a controlled release novel formulation. Although cefepime is a broad spectrum antibiotic, it has various adverse effects and a significant degradation rate. Thus, the preparation and physico-chemical characterization of nanomaterials able to intercalate this drug is an important study for medical and pharmaceutical field. The antibiotic inclusion into LDHs nanostructure was confirmed by advanced characterization techniques and the release profile of cefepime was analysed with the respect to pH of the simulated media.

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