Intrauterine growth of the Guinea pig fetal-placental unit throughout pregnancy: Regulation by utero-placental blood flow

Teratology ◽  
1984 ◽  
Vol 29 (1) ◽  
pp. 93-99 ◽  
Author(s):  
David R. Garris
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Intrauterine Growth ◽  
Placental Blood ◽  
Placental Blood Flow

Effect of terbutaline sulphate on ovarian, uterine and maternal placental blood flow in the anaesthetized guinea pig

1978 ◽  
Vol 53 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Lena Mårtensson ◽  
Per-Ove B. Sjöquist ◽  
Leif Bjellin ◽  
Anthony M. Carter
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Terbutaline Sulphate ◽  
Placental Blood ◽  
Placental Blood Flow

Relationship between placental blood flow and placental and fetal size in guinea pig

1982 ◽  
Vol 243 (3) ◽  
pp. H404-H409 ◽  
Author(s):  
S. A. Myers ◽  
J. W. Sparks ◽  
E. L. Makowski ◽  
G. Meschia ◽  
F. C. Battaglia
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Gestational Age ◽  
Allometric Equation ◽  
Radioactive Microspheres ◽  
Flow Measurements ◽  
Placental Blood ◽  
Fetal Size ◽  
Blood Flow Measurements ◽  
Placental Blood Flow

Blood flow measurements were made using radioactive microspheres in 14 unstressed, conscious, pregnant guinea pigs with gestational age ranging between 34 and 67 days. Within each litter placental blood flow (PBF) was positively correlated to fetal weight (FW), even after correcting for placental weight differences. Although the largest littermate was, on the average, only 30% larger than the smallest, its material placental blood flow was 95% greater. The PBF vs. FW relationship could be described by the allometric equation: PBF = Ai FW2.89 where Ai is a litter-specific coefficient. This study demonstrates that the placenta of the largest littermate is "hyperperfused" compared with its smaller siblings.

Myoendothelial and placental blood flow responses to ritodrine infusion in the guinea pig

1979 ◽  
Vol 135 (3) ◽  
pp. 318-321 ◽  
Author(s):  
Lena Mårtensson ◽  
Per-Ove B. Sjöquist ◽  
Lief Bjellin ◽  
Anthony M. Carter
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Placental Blood ◽  
Placental Blood Flow

The Relation Between Newborn Hemoglobin F Fractions and Risk Factors for Sudden Infant Death Syndrome

2001 ◽  
Vol 125 (2) ◽  
pp. 211-217
Author(s):  
Diana L. Cochran-Black ◽  
Linda D. Cowan ◽  
Barbara R. Neas
Keyword(s):  
Risk Factors ◽  
Blood Flow ◽  
Sudden Infant Death Syndrome ◽  
Intrauterine Growth Restriction ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Hemoglobin F ◽  
Intrauterine Growth ◽  
Placental Blood ◽  
Placental Blood Flow

Abstract Objectives.—The aims of this study were to determine and compare fetal hemoglobin (HbF) fractions at birth in newborns exposed and not exposed to selected factors that have been reported to increase the risk of sudden infant death syndrome (SIDS). Previous studies have implicated HbF in the etiology of SIDS by finding higher fractions in infants dying from SIDS compared to age-matched control infants. Design.—We performed a cross-sectional study using high-performance liquid chromatography to measure HbF fractions in newborn cord blood samples. Exposure to selected risk factors for SIDS was assessed through review of medical records. Participants.—Six hundred thirty-three infants born at Via Christi Regional Medical Center–St Francis Campus, Wichita, Kan, from February 28 through August 5, 1997. Main Outcome Measure.—Hemoglobin F fractions at birth were compared in newborns exposed and not exposed to selected risk factors associated with increased incidence of SIDS. Results.—Mean HbF fractions were significantly higher in preterm newborns of mothers who smoked and in term newborns with intrauterine growth restriction, pregnancy weight gain less than or equal to 9 kg, and pregnancy complications associated with reduced placental blood flow. An elevated newborn HbF fraction, defined as 77% or greater, was significantly associated with maternal smoking, maternal anemia, intrauterine growth restriction, and pregnancy complications associated with reduced placental blood flow. Conclusion.—This study suggests a possible mechanism (HbF) by which previously identified factors may increase the risk of SIDS.

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