5-HT1aagonist ±- 8-OH-DPAT modulates basal and stress-induced changes in medial prefrontal cortical dopamine

Synapse ◽  
1994 ◽  
Vol 18 (3) ◽  
pp. 218-224 ◽  
Author(s):  
Ann M. Rasmusson ◽  
Lee E. Goldstein ◽  
Ariel Y. Deutch ◽  
Benjamin S. Bunney ◽  
Robert H. Roth
Keyword(s):  
Prefrontal Cortical ◽  
Induced Changes ◽  
Medial Prefrontal Cortical

scholarly journals The Neural Sociometer: Brain Mechanisms Underlying State Self-esteem

2011 ◽  
Vol 23 (11) ◽  
pp. 3448-3455 ◽  
Author(s):  
Naomi I. Eisenberger ◽  
Tristen K. Inagaki ◽  
Keely A. Muscatell ◽  
Kate E. Byrne Haltom ◽  
Mark R. Leary
Keyword(s):  
Negative Feedback ◽  
Cortical Activity ◽  
Self Esteem ◽  
Anterior Insula ◽  
Lower State ◽  
Social Connection ◽  
Prefrontal Cortical ◽  
Referential Processing ◽  
Neural Underpinnings ◽  
Medial Prefrontal Cortical

On the basis of the importance of social connection for survival, humans may have evolved a “sociometer”—a mechanism that translates perceptions of rejection or acceptance into state self-esteem. Here, we explored the neural underpinnings of the sociometer by examining whether neural regions responsive to rejection or acceptance were associated with state self-esteem. Participants underwent fMRI while viewing feedback words (“interesting,” “boring“) ostensibly chosen by another individual (confederate) to describe the participant's previously recorded interview. Participants rated their state self-esteem in response to each feedback word. Results demonstrated that greater activity in rejection-related neural regions (dorsal ACC, anterior insula) and mentalizing regions was associated with lower-state self-esteem. Additionally, participants whose self-esteem decreased from prescan to postscan versus those whose self-esteem did not showed greater medial prefrontal cortical activity, previously associated with self-referential processing, in response to negative feedback. Together, the results inform our understanding of the origin and nature of our feelings about ourselves.

Medial prefrontal cortical lesions modulate baroreflex sensitivity in the rat

1987 ◽  
Vol 426 (2) ◽  
pp. 243-249 ◽  
Author(s):  
Anthony J.M. Verberne ◽  
Stephen J. Lewis ◽  
Peter J. Worland ◽  
Philip M. Beart ◽  
Bevyn Jarrott ◽  
...  
Keyword(s):  
Baroreflex Sensitivity ◽  
Cortical Lesions ◽  
Prefrontal Cortical ◽  
Medial Prefrontal Cortical

MEDIAL PREFRONTAL CORTICAL ACTIVATION DURING WORKING MEMORY DIFFERENTIATES SCHIZOPHRENIA AND BIPOLAR PSYCHOTIC PATIENTS: A PILOT STUDY

2010 ◽  
Vol 117 (2-3) ◽  
pp. 355
Author(s):  
Snezana M. Milanovic ◽  
Heidi W. Thermenos ◽  
Ariel Brown ◽  
Jill M. Goldstein ◽  
Susan W. Gabrieli ◽  
...  
Keyword(s):  
Working Memory ◽  
Pilot Study ◽  
Cortical Activation ◽  
Prefrontal Cortical ◽  
Medial Prefrontal Cortical
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