An open-label positron emission tomography study to evaluate serotonin transporter occupancy following escalating dosing regimens of (R
)-(-)-O
-desmethylvenlafaxine and racemic O
-desmethylvenlafaxine

W. Gordon Frankle; Brigitte Robertson; Gary Maier; Jennifer Paris; Deanna Asmonga; Maureen May; Michael L. Himes; N. Scott Mason; Chester A. Mathis; Rajesh Narendran

doi:10.1002/syn.22021

An open-label positron emission tomography study to evaluate serotonin transporter occupancy following escalating dosing regimens of (R )-(-)-O -desmethylvenlafaxine and racemic O -desmethylvenlafaxine

Synapse ◽

10.1002/syn.22021 ◽

2017 ◽

Vol 72 (3) ◽

pp. e22021 ◽

Cited By ~ 1

Author(s):

W. Gordon Frankle ◽

Brigitte Robertson ◽

Gary Maier ◽

Jennifer Paris ◽

Deanna Asmonga ◽

...

Keyword(s):

Positron Emission Tomography ◽

Serotonin Transporter ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Open Label ◽

Positron Emission ◽

Dosing Regimens

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Correction to: An open-label, positron emission tomography study of the striatal D2/D3 receptor occupancy and pharmacokinetics of single-dose oral brexpiprazole in healthy participants

European Journal of Clinical Pharmacology ◽

10.1007/s00228-020-03071-z ◽

2021 ◽

Author(s):

Dean F. Wong ◽

Arash Raoufinia ◽

Patricia Bricmont ◽

James R. Brašić ◽

Robert D. McQuade ◽

...

Keyword(s):

Positron Emission Tomography ◽

Single Dose ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

D3 Receptor ◽

Open Label ◽

Positron Emission ◽

Dose Oral ◽

Healthy Participants

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An open-label, randomized positron emission tomography (PET)study in healthy male volunteers consisiting of Part A and Part B.Part A: Clinical validation of norepinephrine transporter (NET) PET ligand, (S,S)-[11C]O-methylreboxetine ([11C]MRB) using different doses of oral atomoxetine as NET reuptake inhibitor.Part B: Evaluation of NET occupancy, as measured by [11C]MRB, with multiple dosing regimens of orally administered GSK372475.

10.2172/973576 ◽

2007 ◽

Author(s):

Joanna Fowler ◽

Michael Furey

Keyword(s):

Positron Emission Tomography ◽

Norepinephrine Transporter ◽

Emission Tomography ◽

Clinical Validation ◽

Healthy Male ◽

Open Label ◽

Multiple Dosing ◽

Positron Emission ◽

Dosing Regimens ◽

Different Doses

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Brain serotonin transporter binding, plasma arachidonic acid and depression severity: A positron emission tomography study of major depression

Journal of Affective Disorders ◽

10.1016/j.jad.2019.07.035 ◽

2019 ◽

Vol 257 ◽

pp. 495-503 ◽

Cited By ~ 2

Author(s):

Manesh Gopaldas ◽

Francesca Zanderigo ◽

Serena Zhan ◽

R. Todd Ogden ◽

Jeffrey M. Miller ◽

...

Keyword(s):

Positron Emission Tomography ◽

Arachidonic Acid ◽

Major Depression ◽

Serotonin Transporter ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Brain Serotonin ◽

Depression Severity ◽

Positron Emission

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Occupancy of serotonin transporter by tramadol: a positron emission tomography study with [11C]DASB

The International Journal of Neuropsychopharmacology ◽

10.1017/s1461145713001764 ◽

2014 ◽

Vol 17 (06) ◽

pp. 845-850 ◽

Cited By ~ 8

Author(s):

Kohei Ogawa ◽

Amane Tateno ◽

Ryosuke Arakawa ◽

Takeshi Sakayori ◽

Yumiko Ikeda ◽

...

Keyword(s):

Positron Emission Tomography ◽

Serotonin Transporter ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Positron Emission

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Incongruent Reduction of Serotonin Transporter Associated with Suicide Attempts in Patients with Major Depressive Disorder: A Positron Emission Tomography Study with 4-[18F]-ADAM

The International Journal of Neuropsychopharmacology ◽

10.1093/ijnp/pyu065 ◽

2015 ◽

Vol 18 (3) ◽

Cited By ~ 9

Author(s):

Yi-Wei Yeh ◽

Pei-Shen Ho ◽

Chun-Yen Chen ◽

Shin-Chang Kuo ◽

Chih-Sung Liang ◽

...

Keyword(s):

Positron Emission Tomography ◽

Major Depressive Disorder ◽

Depressive Disorder ◽

Serotonin Transporter ◽

Suicide Attempts ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Major Depressive ◽

Positron Emission

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Serotonin transporter in attention-deficit hyperactivity disorder – preliminary results from a positron emission tomography study

Psychiatry Research Neuroimaging ◽

10.1016/j.pscychresns.2013.02.001 ◽

2013 ◽

Vol 212 (2) ◽

pp. 164-165 ◽

Cited By ~ 11

Author(s):

Linnea Karlsson ◽

Lauri Tuominen ◽

Antti Huotarinen ◽

Sami Leppämäki ◽

Elina Sihvola ◽

...

Keyword(s):

Positron Emission Tomography ◽

Attention Deficit Hyperactivity Disorder ◽

Serotonin Transporter ◽

Attention Deficit ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Preliminary Results ◽

Hyperactivity Disorder ◽

Positron Emission

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Serotonin transporter availability in adults with autism—a positron emission tomography study

Molecular Psychiatry ◽

10.1038/s41380-020-00868-3 ◽

2020 ◽

Author(s):

Max Andersson ◽

Ämma Tangen ◽

Lars Farde ◽

Sven Bölte ◽

Christer Halldin ◽

...

Keyword(s):

Positron Emission Tomography ◽

Serotonin Transporter ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Adults With Autism ◽

Positron Emission

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Time-course of serotonin transporter occupancy by single dose of three SSRIs in human brain: A positron emission tomography study with [11C]DASB

Psychiatry Research Neuroimaging ◽

10.1016/j.pscychresns.2016.03.006 ◽

2016 ◽

Vol 251 ◽

pp. 1-6 ◽

Cited By ~ 5

Author(s):

Ryosuke Arakawa ◽

Amane Tateno ◽

WooChan Kim ◽

Takeshi Sakayori ◽

Kohei Ogawa ◽

...

Keyword(s):

Positron Emission Tomography ◽

Single Dose ◽

Human Brain ◽

Serotonin Transporter ◽

Time Course ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Positron Emission

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Serotonin Transporter Occupancy of Five Selective Serotonin Reuptake Inhibitors at Different Doses: An [11C]DASB Positron Emission Tomography Study

American Journal of Psychiatry ◽

10.1176/appi.ajp.161.5.826 ◽

2004 ◽

Vol 161 (5) ◽

pp. 826-835 ◽

Cited By ~ 322

Author(s):

Jeffrey H. Meyer ◽

Alan A. Wilson ◽

Sandra Sagrati ◽

Doug Hussey ◽

Anna Carella ◽

...

Keyword(s):

Positron Emission Tomography ◽

Serotonin Transporter ◽

Serotonin Reuptake ◽

Selective Serotonin Reuptake Inhibitors ◽

Serotonin Reuptake Inhibitors ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Selective Serotonin ◽

Positron Emission ◽

Different Doses

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Relationships between Serotonin Transporter Binding in the Raphe Nuclei, Basal Ganglia, and Hippocampus with Clinical Symptoms in Cervical Dystonia: A [11C]DASB Positron Emission Tomography Study

Frontiers in Neurology ◽

10.3389/fneur.2018.00088 ◽

2018 ◽

Vol 9 ◽

Cited By ~ 4

Author(s):

Marenka Smit ◽

David Vállez García ◽

Bauke M. de Jong ◽

Evelien Zoons ◽

Jan Booij ◽

...

Keyword(s):

Positron Emission Tomography ◽

Basal Ganglia ◽

Serotonin Transporter ◽

Cervical Dystonia ◽

Clinical Symptoms ◽

Emission Tomography ◽

Raphe Nuclei ◽

Positron Emission Tomography Study ◽

Positron Emission ◽

Raphé Nuclei

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