Comparing α7 nicotinic acetylcholine receptor binding, amyloid-β deposition, and mitochondria complex-I function in living brain: A PET study in aged monkeys

Shingo Nishiyama; Hiroyuki Ohba; Masakatsu Kanazawa; Takeharu Kakiuchi; Hideo Tsukada

doi:10.1002/syn.21842

Comparing α7 nicotinic acetylcholine receptor binding, amyloid-β deposition, and mitochondria complex-I function in living brain: A PET study in aged monkeys

Synapse ◽

10.1002/syn.21842 ◽

2015 ◽

Vol 69 (10) ◽

pp. 475-483 ◽

Cited By ~ 6

Author(s):

Shingo Nishiyama ◽

Hiroyuki Ohba ◽

Masakatsu Kanazawa ◽

Takeharu Kakiuchi ◽

Hideo Tsukada

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Binding ◽

Complex I ◽

Amyloid Β ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Mitochondria Complex I

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Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells

Neuroscience ◽

10.1016/j.neuroscience.2014.08.013 ◽

2014 ◽

Vol 278 ◽

pp. 276-290 ◽

Cited By ~ 21

Author(s):

W.N. Yang ◽

K.G. Ma ◽

X.L. Chen ◽

L.L. Shi ◽

G. Bu ◽

...

Keyword(s):

Protein Kinase ◽

Signaling Pathways ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Amyloid Β ◽

Mitogen Activated Protein Kinase ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling

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α7 nicotinic acetylcholine receptor-specific stimulation ameliorates cognitive impairment in a mouse model of Alzheimer's disease via suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.wcp2018.0_or4-4 ◽

2018 ◽

Vol WCP2018 (0) ◽

pp. OR4-4

Author(s):

Kazuyuki Takata ◽

Shohei Kawanishi ◽

Eriko Kuroda ◽

Shigehiko Takegami ◽

Tatsuya Kitade ◽

...

Keyword(s):

Cognitive Impairment ◽

Mouse Model ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Amyloid Β ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Model Of Alzheimer’S Disease ◽

Secretase Activity ◽

Specific Stimulation

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Corrigendum to “Differences in α7 nicotinic acetylcholine receptor binding in motor symptomatic and asymptomatic MPTP-treated monkeys” [Brain Res. 999 (2004) 193–202]

Brain Research ◽

10.1016/j.brainres.2007.05.015 ◽

2007 ◽

Vol 1161 ◽

pp. 124

Author(s):

Jennifer M. Kulak ◽

Jay S. Schneider

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Binding ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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The endogenous α7 nicotinic acetylcholine receptor antagonist kynurenic acid modulates amyloid-β-induced inflammation in BV-2 microglial cells

Journal of the Neurological Sciences ◽

10.1016/j.jns.2014.06.032 ◽

2014 ◽

Vol 344 (1-2) ◽

pp. 94-99 ◽

Cited By ~ 11

Author(s):

Levke Steiner ◽

Maike Gold ◽

David Mengel ◽

Richard Dodel ◽

Jan-Philipp Bach

Keyword(s):

Receptor Antagonist ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Kynurenic Acid ◽

Amyloid Β ◽

Microglial Cells ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Differences in α7 nicotinic acetylcholine receptor binding in motor symptomatic and asymptomatic MPTP-treated monkeys

Brain Research ◽

10.1016/j.brainres.2003.10.062 ◽

2004 ◽

Vol 999 (2) ◽

pp. 193-202 ◽

Cited By ~ 22

Author(s):

Jennifer M. Kulak ◽

Jay S. Schneider

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Binding ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Modulation of α7 Nicotinic Acetylcholine Receptor and Fibrillar Amyloid-β Interactions in Alzheimer's Disease Brain

Journal of Alzheimer s Disease ◽

10.3233/jad-2012-121447 ◽

2013 ◽

Vol 33 (3) ◽

pp. 841-851 ◽

Cited By ~ 41

Author(s):

Ruiqing Ni ◽

Amelia Marutle ◽

Agneta Nordberg

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Amyloid Β ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Nicotine Prevents Synaptic Impairment Induced by Amyloid-β Oligomers Through α7-Nicotinic Acetylcholine Receptor Activation

NeuroMolecular Medicine ◽

10.1007/s12017-013-8242-1 ◽

2013 ◽

Vol 15 (3) ◽

pp. 549-569 ◽

Cited By ~ 48

Author(s):

Nibaldo C. Inestrosa ◽

Juan A. Godoy ◽

Jessica Y. Vargas ◽

Macarena S. Arrazola ◽

Juvenal A. Rios ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Amyloid Β ◽

Receptor Activation ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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α4β2∗ and α7 nicotinic acetylcholine receptor binding predicts choice preference in two cost benefit decision-making tasks

Neuroscience ◽

10.1016/j.neuroscience.2012.10.067 ◽

2013 ◽

Vol 230 ◽

pp. 121-131 ◽

Cited By ~ 15

Author(s):

I.A. Mendez ◽

J.C. Damborsky ◽

U.H. Winzer-Serhan ◽

J.L. Bizon ◽

B. Setlow

Keyword(s):

Decision Making ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Binding ◽

Cost Benefit ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Choice Preference

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Activation of α7 nicotinic acetylcholine receptor alleviates cerebral cortical neuron injury induced by oxygen-glucose deprivation

Academic Journal of Second Military Medical University ◽

10.3724/sp.j.1008.2015.00472 ◽

2015 ◽

Vol 36 (5) ◽

pp. 472

Author(s):

Ru-juan XIN ◽

Ting ZHAO ◽

Min NI ◽

Dong-jie LI ◽

Fu-ming SHEN

Keyword(s):

Cortical Neuron ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Glucose Deprivation ◽

Oxygen Glucose Deprivation ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Cerebral Cortical Neuron ◽

Neuron Injury

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Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113189 ◽

2021 ◽

Vol 214 ◽

pp. 113189

Author(s):

István Ledneczki ◽

Pál Tapolcsányi ◽

Eszter Gábor ◽

András Visegrády ◽

Márton Vass ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Allosteric Modulators ◽

Scaffold Hopping ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Positive Allosteric Modulators

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