Prenatal stress alters limbo-corticostriatal homer protein expression

Synapse ◽  
2007 ◽  
Vol 61 (11) ◽  
pp. 938-941 ◽  
Author(s):  
Alexis W. Ary ◽  
Valerie R. Aguilar ◽  
Karen K. Szumlinski ◽  
Tod E. Kippin
Keyword(s):  
Protein Expression ◽  
Prenatal Stress ◽  
Homer Protein

Prenatal stress alters Fos protein expression in hippocampus and locus coeruleus stress-related brain structures

2006 ◽  
Vol 31 (6) ◽  
pp. 769-780 ◽  
Author(s):  
Odile Viltart ◽  
Jérôme Mairesse ◽  
Muriel Darnaudéry ◽  
Hélène Louvart ◽  
Christel Vanbesien-Mailliot ◽  
...  
Keyword(s):  
Protein Expression ◽  
Locus Coeruleus ◽  
Prenatal Stress ◽  
Brain Structures ◽  
Fos Protein

Sex-Specific Effects of Prenatal Stress on Memory and Markers of Neuronal Activity in Juvenile Rats

2016 ◽  
Vol 38 (3) ◽  
pp. 206-219 ◽  
Author(s):  
Yael Barbie-Shoshani ◽  
Shai Shoham ◽  
Corina Bejar ◽  
Marta Weinstock
Keyword(s):  
Protein Expression ◽  
Neuronal Activity ◽  
Spatial Learning ◽  
Prenatal Stress ◽  
Statistical Significance ◽  
Staining Intensity ◽  
Adult Brain ◽  
Plasma Testosterone ◽  
Juvenile Rats ◽  
Prenatally Stressed

Stress during pregnancy can increase the incidence of emotional problems, learning and language difficulties in human infants and pre-adolescents. Most preclinical studies in rats that attempted to find experimental support for these observations were performed in adult male offspring, but the results are inconsistent. The aim of the current study was to examine the effect of prenatal stress on novel object recognition (NOR) and spatial learning and memory in the Morris water maze (MWM) of juvenile rats of both sexes. By the use of fluorescence immunohistochemistry and protein measurements by Western blot, we measured the expression of markers of neurogenesis (doublecortin, DCX) and neuronal activity that are important for synaptic plasticity and learning (c-fos, GluR1, nNOS). Since neuronal activity in the developing and adult brain can be regulated by astrocytes, we also measured the number of astrocytes and the expression of two astroglial proteins (GFAP and S100B) in the stress-responsive hippocampal dentate gyrus (DG). Experiments were performed on littermates of rats in which its effects on behavior were measured. We found for the first time that juvenile females performed better than males in the NOR and MWM tests. They also had higher densities of DCX and c-fos in the DG, together with the expression of nNOS and GluR1 in the subgranular zone (SGZ) of the DG. There were no sex differences in the expression of GFAP and S100B in astrocytes. Prenatal stress did not affect NOR in females, but improved it in males, together with an increase in DCX+ and c-fos, the number of GFAP-expressing astrocytes and the intensity of GFAP and S100B immunofluorescence in the DG. Staining intensity of GluR1 and nNOS in the hilus and SGZ of the DG, and protein expression in the whole DG, was unchanged in prenatally stressed males. Thus, prenatal stress changed the behavior and expression of key proteins in the DG to resemble that in females. A reduction in plasma testosterone, which although not attaining statistical significance was associated with that in anogenital distance, may contribute to the effect of prenatal stress in males. In females, prenatal stress had no effect on c-fos, DCX or the number of astrocytes but reduced the staining intensity of GluR1 and nNOS. Protein expression of nNOS was also significantly lower than that in prenatally stressed males. The differential effects of prenatal stress on hippocampal neuronal and glial markers may help to explain the sex-dependent effect on spatial learning in prepubertal rats.

CFTR protein expression in healthy men spermatozoa is not correlated with fertilization rate of ova

2010 ◽  
Vol 34 (8) ◽  
pp. S12-S12
Author(s):  
Hong‑Ge Li ◽  
Chen Min Xu ◽  
Kun Li ◽  
Ya Ni ◽  
Wen‑Ying Chen ◽  
...  
Keyword(s):  
Protein Expression ◽  
Fertilization Rate ◽  
Healthy Men ◽  
Cftr Protein

Bone sialoprotein mRNA and protein expression in human multiple myeloma cell lines and patients

2000 ◽  
Vol 111 (4) ◽  
pp. 1118-1121 ◽  
Author(s):  
A. Bellahcene ◽  
I. Van Riet ◽  
C. de Greef ◽  
N. Antoine ◽  
M. F. Young ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Protein Expression ◽  
Cell Lines ◽  
Myeloma Cell ◽  
Bone Sialoprotein ◽  
Multiple Myeloma Cell ◽  
Human Multiple Myeloma ◽  
Mrna And Protein Expression

660: Altered MUC-1 (EMA) Protein Expression Studied by Tissue Microarray Predicts Biochemical Failure after Radical Prostatectomy in Prostate Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 222-222
Author(s):  
Mireia Musquera ◽  
Maria J. Ribal ◽  
Yolanda Arce ◽  
Humberto Villavicencio ◽  
Fernando Algaba ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Protein Expression ◽  
Tissue Microarray ◽  
Biochemical Failure

1002: The Pathogenesis of Peyronie's Disease: Can Protein Expression Predict Progression

2006 ◽  
Vol 175 (4S) ◽  
pp. 323-323
Author(s):  
Gerald B. Brock ◽  
Ling De Young ◽  
Bing Siang Gan ◽  
Anthony J. Bella ◽  
Kok Bin Lim
Keyword(s):  
Protein Expression ◽  
Peyronie’S Disease ◽  
Peyronie's Disease

405: Alpha-Methylacyl-CoA Racemase (AMACR/P504S) Protein Expression in Urothelial Carcinoma of the Upper Urinary Tract Correlates with Tumour Progression

2006 ◽  
Vol 175 (4S) ◽  
pp. 132-132
Author(s):  
Richard E. Zigeuner ◽  
Sebastian Leibl ◽  
Georg Hutterer ◽  
Thomas Chromecki ◽  
Peter Rehak ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Protein Expression ◽  
Urothelial Carcinoma ◽  
Tumour Progression ◽  
Upper Urinary Tract
Sign in / Sign up

Export Citation Format

Share Document