scholarly journals Wip1 Regulates the Generation of New Neural Cells in the Adult Olfactory Bulb through p53-Dependent Cell Cycle Control

Stem Cells ◽  
2009 ◽  
Vol 27 (6) ◽  
pp. 1433-1442 ◽  
Author(s):  
Yun-Hua Zhu ◽  
Cheng-Wu Zhang ◽  
Li Lu ◽  
Oleg N. Demidov ◽  
Li Sun ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Olfactory Bulb ◽  
Cell Cycle Control ◽  
Neural Cells ◽  
Dependent Cell

scholarly journals Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer

2017 ◽  
Vol 7 (10) ◽  
pp. 1168-1183 ◽  
Author(s):  
Svasti Haricharan ◽  
Nindo Punturi ◽  
Purba Singh ◽  
Kimberly R. Holloway ◽  
Meenakshi Anurag ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Endocrine Therapy ◽  
Primary Breast Cancer ◽  
Cell Cycle Control ◽  
Therapy Resistance ◽  
Endocrine Therapy Resistance ◽  
Dependent Cell

scholarly journals Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer

Oncotarget ◽  
2015 ◽  
Vol 7 (1) ◽  
pp. 622-637 ◽  
Author(s):  
Nithyananda Thorenoor ◽  
Petra Faltejskova-Vychytilova ◽  
Sonja Hombach ◽  
Jitka Mlcochova ◽  
Markus Kretz ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Cycle ◽  
Cell Cycle Control ◽  
Non Coding Rna ◽  
Dependent Cell ◽  
Long Non Coding Rna

scholarly journals The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans

Blood ◽  
2012 ◽  
Vol 120 (26) ◽  
pp. 5118-5127 ◽  
Author(s):  
Vinod Pant ◽  
Alfonso Quintás-Cardama ◽  
Guillermina Lozano
Keyword(s):  
Cell Cycle ◽  
Stem Cell ◽  
Mouse Models ◽  
Cell Function ◽  
Cell Cycle Control ◽  
Hematologic Malignancies ◽  
Genetically Engineered ◽  
Hematopoietic Stem ◽  
Genetically Engineered Mice ◽  
Dependent Cell

Abstract Aberrations in the p53 tumor suppressor pathway are associated with hematologic malignancies. p53-dependent cell cycle control, senescence, and apoptosis functions are actively involved in maintaining hematopoietic homeostasis under normal and stress conditions. Whereas loss of p53 function promotes leukemia and lymphoma development in humans and mice, increased p53 activity inhibits hematopoietic stem cell function and results in myelodysplasia. Thus, exquisite regulation of p53 activity is critical for homeostasis. Most of our understanding of p53 function in hematopoiesis is derived from genetically engineered mice. Here we summarize some of these models, the various mechanisms that disrupt the regulation of p53 activity, and their relevance to human disease.

ChemInform Abstract: The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control

ChemInform ◽  
2009 ◽  
Vol 40 (26) ◽  
Author(s):  
Katherine Wickliffe ◽  
Adam Williamson ◽  
Lingyan Jin ◽  
Michael Rape
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Control ◽  
Dependent Cell

scholarly journals Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control

2020 ◽  
Vol 30 (14) ◽  
pp. 2829-2835.e5
Author(s):  
Emily K. Ho ◽  
Anaïs E. Tsai ◽  
Tim Stearns
Keyword(s):  
Cell Cycle ◽  
Primary Cilia ◽  
Cell Cycle Control ◽  
Hedgehog Pathway ◽  
Dependent Cell

scholarly journals The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control

2009 ◽  
Vol 109 (4) ◽  
pp. 1537-1548 ◽  
Author(s):  
Katherine Wickliffe ◽  
Adam Williamson ◽  
Lingyan Jin ◽  
Michael Rape
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Control ◽  
Dependent Cell
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