Directly reprogrammed Huntington's disease neural precursor cells generate striatal neurons exhibiting aggregates and impaired neuronal maturation

Ruth Monk; Kevin Lee; Kathryn S. Jones; Bronwen Connor

doi:10.1002/stem.3420

Directly reprogrammed Huntington's disease neural precursor cells generate striatal neurons exhibiting aggregates and impaired neuronal maturation

Stem Cells ◽

10.1002/stem.3420 ◽

2021 ◽

Vol 39 (10) ◽

pp. 1410-1422

Author(s):

Ruth Monk ◽

Kevin Lee ◽

Kathryn S. Jones ◽

Bronwen Connor

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor ◽

Neuronal Maturation ◽

Striatal Neurons

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Proliferating Neural Precursor Cells as First Step toward Neuroregeneration in Huntington's Disease?

Journal of Neuroscience ◽

10.1523/jneurosci.4832-06.2006 ◽

2006 ◽

Vol 26 (52) ◽

pp. 13411-13412 ◽

Cited By ~ 3

Author(s):

M. M. Y. Fan ◽

J. Fan

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor

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Transplantation of GABAergic Cells Derived from Bioreactor-Expanded Human Neural Precursor Cells Restores Motor and Cognitive Behavioral Deficits in a Rodent Model of Huntington's Disease

Cell Transplantation ◽

10.3727/096368912x658809 ◽

2013 ◽

Vol 22 (12) ◽

pp. 2237-2256 ◽

Cited By ~ 8

Author(s):

Marcus C. McLeod ◽

Nao R. Kobayashi ◽

Arindom Sen ◽

Behnam A. Baghbaderani ◽

Damaso Sadi ◽

...

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Precursor Cells ◽

Rodent Model ◽

Neural Precursor Cells ◽

Cognitive Behavioral ◽

Neural Precursor ◽

Behavioral Deficits

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Human iPSC‐derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model

Cell Proliferation ◽

10.1111/cpr.13082 ◽

2021 ◽

Author(s):

Hyun Jung Park ◽

Juhyun Jeon ◽

Jiwoo Choi ◽

Ji Yeon Kim ◽

Hyun Sook Kim ◽

...

Keyword(s):

Mouse Model ◽

Huntington's Disease ◽

Disease Progression ◽

Cell Types ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor ◽

Delay Disease Progression ◽

Multiple Cell ◽

Human Ipsc

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Dopaminergic stimulation in a transgenic model of neurodegeneration restores decreased proliferation and viability in subventricular zone derived adult neural precursor cells

Pharmacopsychiatry ◽

10.1055/s-0035-1558039 ◽

2015 ◽

Vol 48 (06) ◽

Author(s):

J Vogelgsang ◽

J Wiltfang ◽

E Masliah ◽

J Winkler ◽

J Klucken

Keyword(s):

Subventricular Zone ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor ◽

Transgenic Model ◽

Dopaminergic Stimulation

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Dopaminergic stimulation in a transgenic model of neurodegeneration restores decreased proliferation and viability in subventricular zone derived adult neural precursor cells

Pharmacopsychiatry ◽

10.1055/s-0035-1558001 ◽

2015 ◽

Vol 48 (06) ◽

Author(s):

J Vogelgsang ◽

J Wiltfang ◽

E Masliah ◽

J Winkler ◽

J Klucken

Keyword(s):

Subventricular Zone ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor ◽

Transgenic Model ◽

Dopaminergic Stimulation

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NPHP3 expression in ciliated neural precursor cells of the cerebellum suggests a specific function of nephrocystin-3 for cerebellar development

Neuropediatrics ◽

10.1055/s-2004-819375 ◽

2004 ◽

Vol 35 (01) ◽

Author(s):

M Fliegauf ◽

H Olbrich ◽

A Kispert ◽

H Omran

Keyword(s):

Precursor Cells ◽

Neural Precursor Cells ◽

Cerebellar Development ◽

Neural Precursor ◽

Specific Function

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Faculty Opinions recommendation of Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1165143.628207 ◽

2009 ◽

Author(s):

Susan K McConnell

Keyword(s):

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor

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Faculty Opinions recommendation of Magnetic resonance imaging of odorant activity-dependent migration of neural precursor cells and olfactory bulb growth.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727772737.793534121 ◽

2017 ◽

Author(s):

Pierre-Marie Lledo

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Olfactory Bulb ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor ◽

Resonance Imaging ◽

Activity Dependent

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Faculty Opinions recommendation of Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732609529.793548926 ◽

2018 ◽

Author(s):

David Schaffer ◽

Maroof Adil

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Disease Patient ◽

Striatal Neurons ◽

Disease Phenotypes

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Faculty Opinions recommendation of A novel long noncoding RNA lnc158 promotes the differentiation of mouse neural precursor cells into oligodendrocytes by targeting nuclear factor-IB.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733759619.793570347 ◽

2020 ◽

Author(s):

Q Richard Lu ◽

Kalen Berry

Keyword(s):

Long Noncoding Rna ◽

Noncoding Rna ◽

Precursor Cells ◽

Neural Precursor Cells ◽

Neural Precursor ◽

Nuclear Factor

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