scholarly journals Oct4 and Klf4 Reprogram Dermal Papilla Cells into Induced Pluripotent Stem Cells

Stem Cells ◽  
2009 ◽  
pp. N/A-N/A ◽  
Author(s):  
Su-Yi Tsai ◽  
Carlos Clavel ◽  
Soo Kim ◽  
Yen-Sin Ang ◽  
Laura Grisanti ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dermal Papilla ◽  
Dermal Papilla Cells ◽  
Induced Pluripotent

scholarly journals Single Transcription Factor Reprogramming of Hair Follicle Dermal Papilla Cells to Induced Pluripotent Stem Cells

Stem Cells ◽  
2011 ◽  
Vol 29 (6) ◽  
pp. 964-971 ◽  
Author(s):  
Su-Yi Tsai ◽  
Britta Am Bouwman ◽  
Yen-Sin Ang ◽  
Soo Jeong Kim ◽  
Dung-Fang Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Transcription Factor ◽  
Induced Pluripotent Stem Cells ◽  
Hair Follicle ◽  
Pluripotent Stem Cells ◽  
Dermal Papilla ◽  
Dermal Papilla Cells ◽  
Induced Pluripotent

scholarly journals Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells

2012 ◽  
Vol 132 (6) ◽  
pp. 1725-1727 ◽  
Author(s):  
Claire A. Higgins ◽  
Munenari Itoh ◽  
Keita Inoue ◽  
Gavin D. Richardson ◽  
Colin A.B. Jahoda ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Hair Follicle ◽  
Pluripotent Stem Cells ◽  
Human Hair ◽  
Dermal Papilla ◽  
Human Hair Follicle ◽  
Dermal Papilla Cells ◽  
Induced Pluripotent

scholarly journals Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures

2018 ◽  
Vol 2018 ◽  
pp. 1-14
Author(s):  
Jun Liu ◽  
Claire A. Higgins ◽  
Jenna C. Whitehouse ◽  
Susan J. Harris ◽  
Heather Crawford ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Hair Follicle ◽  
Pluripotent Stem Cells ◽  
Embryonic Stem ◽  
Dermal Papilla ◽  
Epithelial Stem Cells ◽  
Stem Cell Maintenance ◽  
Induced Pluripotent ◽  
Dermal Cells

In the hair follicle, the dermal papilla (DP) and dermal sheath (DS) support and maintain proliferation and differentiation of the epithelial stem cells that produce the hair fibre. In view of their regulatory properties, in this study, we investigated the interaction between hair follicle dermal cells (DP and DS) and embryonic stem cells (ESCs); induced pluripotent stem cells (iPSCs); and haematopoietic stem cells. We found that coculture of follicular dermal cells with ESCs or iPSCs supported their prolonged maintenance in an apparently undifferentiated state as established by differentiation assays, immunocytochemistry, and RT-PCR for markers of undifferentiated ESCs. We further showed that cytokines that are involved in ESC support are also expressed by cultured follicle dermal cells, providing a possible explanation for maintenance of ES cell stemness in cocultures. The same cytokines were expressed within folliclesin situin a pattern more consistent with a role in follicle growth activities than stem cell maintenance. Finally, we show that cultured mouse follicle dermal cells provide good stromal support for haematopoiesis in an established coculture model. Human follicular dermal cells represent an accessible and readily propagated source of feeder cells for pluripotent and haematopoietic cells and have potential for use in clinical applications.

Directed differentiation of mouse-induced pluripotent stem cells generates dopaminergic nerve

2010 ◽  
Vol 34 (8) ◽  
pp. S36-S36
Author(s):  
Ping Duan ◽  
Xuelin Ren ◽  
Wenhai Yan ◽  
Xuefei Han ◽  
Xu Yan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Directed Differentiation ◽  
Induced Pluripotent
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