Effect of sodium alginate and its guluronic acid/mannuronic acid ratio on the physicochemical properties of high-amylose cornstarch

2016 ◽  
Vol 68 (11-12) ◽  
pp. 1215-1223 ◽  
Author(s):  
Yang Zhao ◽  
HaiHua Chen ◽  
YuSheng Wang ◽  
QianQian Li
Marine Drugs ◽  
2020 ◽  
Vol 18 (10) ◽  
pp. 520
Author(s):  
Masanori Mori ◽  
Rintaro Asahi ◽  
Yoshihiro Yamamoto ◽  
Takanobu Mashiko ◽  
Kayo Yoshizumi ◽  
...  

Filler injection demand is increasing worldwide, but no ideal filler with safety and longevity currently exists. Sodium alginate (SA) is the sodium salt of alginic acid, which is a polymeric polysaccharide obtained by linear polymerization of two types of uronic acid, d-mannuronic acid (M) and l-guluronic acid (G). This study aimed to evaluate the therapeutic value of SA. Nine SA types with different M/G ratios and viscosities were tested and compared with a commercially available sodium hyaluronate (SH) filler. Three injection modes (onto the periosteum, intradermally, or subcutaneously) were used in six rats for each substance, and the animals were sacrificed at 4 or 24 weeks. Changes in the diameter and volume were measured macroscopically and by computed tomography, and histopathological evaluations were performed. SA with a low M/G ratio generally maintained skin uplift. The bulge gradually decreased over time but slightly increased at 4 weeks in some samples. No capsule formation was observed around SA. However, granulomatous reactions, including macrophage recruitment, were observed 4 weeks after SA implantation, although fewer macrophages and granulomatous reactions were observed at 24 weeks. The long-term volumizing effects and degree of granulomatous reactions differed depending on the M/G ratio and viscosity. By contrast, SH showed capsule formation but with minimal granulomatous reactions. The beneficial and adverse effects of SA as a filler differed according to the viscosity or M/G ratio, suggesting a better long-term volumizing effect than SH with relatively low immunogenicity


1966 ◽  
Vol 44 (9) ◽  
pp. 993-998 ◽  
Author(s):  
P. A. J. Gorin ◽  
J. F. T. Spencer

Azotobactervinelandii produces a partly acetylated exocellular polysaccharide which consists mainly of D-mannuronic acid units and a small proportion of L-guluronic acid units. It resembles alginic acid since it contains 4-O-linked mannuronosyl residues and guluronosyl residues which are 4-O- and (or) 5-O-linked. The specific rotation of bacterial sodium alginate is close to that of its algal counterpart, thus suggesting that the glycosidic configurations are similar.


Author(s):  
S. Inoue ◽  
Y. Tanaka ◽  
S.C. Skoryna

Sodium alginate, a brown seaweed polysaccharide, is capable of preventing intestinal absorption of radioactive strontium and its radiotoxicological importance is now well established. Alginic acid was found to be composed of 1,4-linked poly-L-guluronic acid and poly-D-mannuronic acid chains with some glycosidic linkages between these uronic acids.Polyguluronic and polymannuronic acid were prepared by acid hydrolysis of alginic acid from Laminaria hyperborea followed by fractionation of the partially degraded sodium alginate at pH 2.8. These components consist almost exclusively of a single uronic acid (polyguluronic acid: man/gul = 0.27; polymannuronic acid: man/gul = 10.7). Sodium polyguluronate inhibits absorption of radiostrontium more effectively than sodium polymannuronate.


Molecules ◽  
2019 ◽  
Vol 24 (23) ◽  
pp. 4374 ◽  
Author(s):  
Wenxiao Jiao ◽  
Wenxue Chen ◽  
Yuqi Mei ◽  
Yonghuan Yun ◽  
Boqiang Wang ◽  
...  

The aim of this study was to prepare sodium alginates (SAs) with different molecular weight and G/M ratio, and characterize their rheological behaviors and emulsifying properties. The result of Fourier transform infrared (FTIR) showed that the chemical bonds among the β-d-mannuronic acid- (M-), α-l-guluronic acid- (G-), and MG-sequential blocks in the SA chains were not changed significantly by acid treatment. Meanwhile, the molecular weight and G/M ratio of the SA exhibited drastic variation after acid modification. The result of rheological analysis suggesting that the apparent viscosity of SA reduced from 30 to 16.4 mPa.s with the increase of shear rate, reveals that SA solution belongs to pseudoplastic liquid. Also, the apparent viscosity of acid-modified SA solution dropped rapidly with the decrease of the molecular weight. The properties of emulsions stabilized by SA, SA-Ms, and commercial SAs were evaluated via the interface tensiometry and determination of the zeta potential, droplet size, creaming index (CI), and Turbiscan stability index (TSI). Compared with the SA-stabilized emulsion, the interfacial tension of the emulsion stabilized by SA-M increased with the decrease of the molecular weight reduced at the similar M/G ratio. The decrease in zeta potential and the increase in TSI of the emulsion were observed with the decrease of molecular weight, indicating that molecular weight plays an important role on the emulsifying ability of SA. In addition, the SA with low G/M ratio can form emulsions with stable and fine droplets.


1972 ◽  
Vol 20 (5) ◽  
pp. 358-367 ◽  
Author(s):  
VALERIE VREELAND

Fluorescent and peroxidase-labeled antibody techniques were employed to localize alginate, which is one component in the complex extracellular acidic polysaccharide situation of the brown seaweed, Fucus distichus. The alginate antigen was extracted and characterized by a variety of methods. It had a low degree of polymerization and a mannuronic acid to guluronic acid ratio of 2.2. No contaminants were detected. The specificity of rabbit antisera was tested by immunodiffusion. Antisera reacted with alginate and fractions of alginate but not with other brown algal polysaccharides. When cryostat sections of Fucus proved unsuitable, 1-µ sections embedded in glycol methacrylate were used for indirect fluorescent or peroxidase antibody staining. Highly sulfated extracellular polysaccharides and intracellular phenolic compounds were implicated in nonspecific staining. Texture artifacts were caused by solubility of alginates and other polysaccharides from embedded sections. Alginate was localized in variable patterns in all cell walls and some matrix regions. The applicability of the methods is discussed.


2018 ◽  
Vol 81 ◽  
pp. 442-448 ◽  
Author(s):  
Maria J. Costa ◽  
Arlete M. Marques ◽  
Lorenzo M. Pastrana ◽  
José A. Teixeira ◽  
Sanna M. Sillankorva ◽  
...  

2021 ◽  
Vol 99 ◽  
pp. 103183
Author(s):  
Zekun Xu ◽  
Yijuan Xu ◽  
Xiaojing Chen ◽  
Lin Zhang ◽  
Haitao Li ◽  
...  

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