Direct and simultaneous determination of methionine sulfoxide and pyroglutamic acid impurities in Compound Amino Acid Injection-18 AA by ion-pair reversed-phase HPLC

2018 ◽  
Vol 1 (7) ◽  
pp. 483-489 ◽  
Author(s):  
Li Li ◽  
Yaru Qin ◽  
Bingyuan Ma ◽  
Hongyan Cui ◽  
Ping Qiao ◽  
...  
Glycobiology ◽  
2010 ◽  
Vol 20 (7) ◽  
pp. 865-871 ◽  
Author(s):  
Kazuki Nakajima ◽  
Shinobu Kitazume ◽  
Takashi Angata ◽  
Reiko Fujinawa ◽  
Kazuaki Ohtsubo ◽  
...  

2009 ◽  
Vol 42 (18) ◽  
pp. 2951-2961 ◽  
Author(s):  
Marie-Hélène Langlois ◽  
Philippe Dallet ◽  
Tina Kauss ◽  
Jean-Pierre Dubost

2011 ◽  
Vol 8 (1) ◽  
pp. 340-346 ◽  
Author(s):  
Rajesh M. Kashid ◽  
Santosh G. Singh ◽  
Shrawan Singh

A reversed phase HPLC method that allows the separation and simultaneous determination of the preservatives methyl paraben (M.P.) and propyl paraben (P.P.) is described. The separations were effected by using an initial mobile phase of water: acetonitrile (50:50) on Inertsil C18 to elute P.P. and M.P. The detector wavelength was set at 205 nm. Under these conditions, separation of the two components was achieved in less than 10 min. Analytical characteristics of the separation such as precision, specificity, linear range and reproducibility were evaluated. The developed method was applied for the determination of preservative M.P. and P.P. at concentration of 0.01 mg/mL and 0.1 mg/mL respectively. The method was successfully used for determining both compounds in sucralfate suspension.


1984 ◽  
Vol 17 (5) ◽  
pp. 423-431 ◽  
Author(s):  
L. Gagliardi ◽  
G. Cavazzutti ◽  
A. Amato ◽  
V. Zagarese ◽  
F. Chimenit ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document