Upconversion Nanocarriers Encapsulated with Photoactivatable Ru Complexes for Near-Infrared Light-Regulated Enzyme Activity

Small ◽  
2017 ◽  
Vol 13 (46) ◽  
pp. 1700997 ◽  
Author(s):  
Zhijun Chen ◽  
Raweewan Thiramanas ◽  
Mischa Schwendy ◽  
Chaoming Xie ◽  
Sapun H. Parekh ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Ru Complexes

Dynamic Modulation of Enzyme Activity by Near-Infrared Light

2017 ◽  
Vol 129 (24) ◽  
pp. 6871-6876 ◽  
Author(s):  
Changping Wang ◽  
Qiang Zhang ◽  
Xinyu Wang ◽  
Hong Chang ◽  
Sanjun Zhang ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Dynamic Modulation

Dynamic Modulation of Enzyme Activity by Near-Infrared Light

2017 ◽  
Vol 56 (24) ◽  
pp. 6767-6772 ◽  
Author(s):  
Changping Wang ◽  
Qiang Zhang ◽  
Xinyu Wang ◽  
Hong Chang ◽  
Sanjun Zhang ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Dynamic Modulation

scholarly journals Off-on switching of enzyme activity by near-infrared light-induced photothermal phase transition of nanohybrids

2019 ◽  
Vol 5 (8) ◽  
pp. eaaw4252 ◽  
Author(s):  
Song Zhang ◽  
Changping Wang ◽  
Hong Chang ◽  
Qiang Zhang ◽  
Yiyun Cheng
Keyword(s):  
Phase Transition ◽  
Enzyme Activity ◽  
Near Infrared ◽  
Infrared Light ◽  
Solution Temperature ◽  
Photothermal Effect ◽  
Platinum Nanoparticle ◽  
Near Infrared Light ◽  
Upper Critical Solution Temperature ◽  
New Strategy

The off-on manipulation of enzyme activity is a challenging task. We report a new strategy for reversible off-on control of enzyme activity by near-infrared light. Enzymes acting on macromolecular substrates are embedded with an ultrasmall platinum nanoparticle and decorated with thermoresponsive copolymers, which exhibit upper critical solution temperature (UCST) behavior. The polymer-enzyme nanohybrids form microscale aggregates in solution below the UCST to prevent macromolecular substrates from approaching the enzymes and thus inhibit the enzyme activity, and they disassemble above the UCST to reactivate the enzyme. Upon near-infrared irradiation, platinum nanoparticles inside the enzymes generate heat through a photothermal effect to cause phase transition of the copolymers. Therefore, we can reversibly switch off and on the activities of three enzymes acting on polysaccharide, protein, and plasmid. The enzyme activities are increased by up to 61-fold after laser irradiation. This study provides a facile and efficient method for off-on control of enzyme activity.

An ordered copper nanowell-array film with near-perfect broadband absorption from ultraviolet to near-infrared light

2020 ◽  
Vol 59 (11) ◽  
pp. 110906
Author(s):  
Juan Shen ◽  
Yong Ren ◽  
Xinxin Zhu ◽  
Min Mao ◽  
Quan Zhou ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Broadband Absorption

scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

2021 ◽  
Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Human Society ◽  
Near Infrared Light ◽  
History Of ◽  
The Universe

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

scholarly journals Au–ZnO Conjugated Black Phosphorus as a Near-Infrared Light-Triggering and Recurrence-Suppressing Nanoantibiotic Platform against Staphylococcus aureus

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 52
Author(s):  
Atanu Naskar ◽  
Sohee Lee ◽  
Kwang-sun Kim
Keyword(s):  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Au Nanoparticles ◽  
Synthesis Method ◽  
Antibacterial Properties ◽  
Black Phosphorus ◽  
Infrared Light ◽  
Resistant Bacteria ◽  
Near Infrared Light

Antibiotic therapy is the gold standard for bacterial infections treatment. However, the rapid increase in multidrug-resistant (MDR) bacterial infections and its recent use for secondary bacterial infections in many COVID-19 patients has considerably weakened its treatment efficacy. These shortcomings motivated researchers to develop new antibacterial materials, such as nanoparticle-based antibacterial platform with the ability to increase the chances of killing MDR strains and prevent their drug resistance. Herein, we report a new black phosphorus (BP)-based non-damaging near-infrared light-responsive platform conjugated with ZnO and Au nanoparticles as a synergistic antibacterial agent against Staphylococcus aureus species. First, BP nanosheets containing Au nanoparticles were assembled in situ with the ZnO nanoparticles prepared by a low-temperature solution synthesis method. Subsequently, the antibacterial activities of the resulting Au–ZnO–BP nanocomposite against the non-resistant, methicillin-resistant, and erythromycin-resistant S. aureus species were determined, after its photothermal efficacy was assessed. The synthesized nanocomposite exhibited excellent anti-S. aureus activity and good photothermal characteristics. The non-resistant S. aureus species did not produce drug-resistant bacteria after the treatment of multiple consecutive passages under the pressure of the proposed nanoantibiotic, but rapidly developed resistance to erythromycin. This work clearly demonstrates the excellent photothermal antibacterial properties of Au–ZnO–BP nanocomposite against the MDR S. aureus species.

π-Conjugated Copolymers Composed of Boron Formazanate and Their Application for a Wavelength Converter to Near-Infrared Light

2021 ◽  
Vol 54 (4) ◽  
pp. 1934-1942
Author(s):  
Yuki Kawano ◽  
Yoshinori Ito ◽  
Shunichiro Ito ◽  
Kazuo Tanaka ◽  
Yoshiki Chujo
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Wavelength Converter ◽  
Near Infrared Light ◽  
Conjugated Copolymers
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