High-Performance Upconversion Nanoprobes for Multimodal MR Imaging of Acute Ischemic Stroke

Small ◽  
2016 ◽  
Vol 12 (26) ◽  
pp. 3591-3600 ◽  
Author(s):  
Jing Wang ◽  
Hua Zhang ◽  
Dalong Ni ◽  
Wenpei Fan ◽  
Jianxun Qu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Mr Imaging ◽  
Acute Ischemic Stroke ◽  
High Performance

Stand alone mechanical thrombectomy (with penumbra system) for acute ischemic stroke based on MR imaging: Single center experience

2012 ◽  
Vol 60 (4) ◽  
pp. 406
Author(s):  
Manish Shrivastava ◽  
Darshana Sanghvi ◽  
Shirish Hastak ◽  
Sourabh Lahoti ◽  
Annu Aggarwal
Keyword(s):  
Ischemic Stroke ◽  
Mr Imaging ◽  
Acute Ischemic Stroke ◽  
Mechanical Thrombectomy ◽  
Single Center ◽  
Single Center Experience

Abstract WP39: Mechanical Embolectomy for Acute Ischemic Stroke Beyond Six Hours From Symptom Onset Using Advanced MR Imaging

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Ryan McTaggart ◽  
Shadi Yaghi ◽  
Daniel C Sacchetti ◽  
Richard Haas ◽  
Shawna Cutting ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Mr Imaging ◽  
Acute Ischemic Stroke ◽  
Large Vessel ◽  
Lesion Volume ◽  
Large Artery ◽  
Large Vessel Occlusion ◽  
Anterior Circulation ◽  
Vessel Occlusion ◽  
Good Outcome

Background: There is very limited data on the use of advanced neuroimaging to select patients with acute ischemic stroke and large vessel occlusion for intraarterial therapy beyond 6 hours from onset. Our aim is to report the outcome of patients with acute ischemic stroke and large artery occlusion who presented beyond 6 hours from onset, had favorable MRI imaging profile, and underwent mechanical embolectomy. Methods: This is a single institution retrospective study between December 1st, 2015, and July 30 th , 2016 with acute ischemic stroke and anterior circulation large vessel occlusion (LVO) with ASPECTS of 6 or more and beyond 6 hours from symptoms onset. Favorable imaging profile was defined as 1) DWI lesion volume (as defined as apparent diffusion coefficient < 620 X 10-6 mm2/s) of 70 mL or less AND 2) Penumbra volume (as defined by volume of tissue with Tmax >6 sec) of 15 mL or greater AND 3) A mismatch ratio of 1.8 or more AND 4) Volume of tissue with perfusion lesion with Tmax > 10 sec is less than 100 mL. Good outcome was defined as a 90 day mRS≤2. Results: In the study period, 41 patients met the inclusion criteria; 22 (53.6%) had favorable imaging profile and underwent mechanical embolectomy. The median age was 75 years (59-92), 68.2% were females; the median time from last known normal to groin puncture was 684.5 minutes (range 363-1628) and the median admission NIHSS score was 17.5 (range 4-28). The rate of good outcomes in this series was similar to that in a patient level pooled meta-analysis of the recent endovascular trials (68.2% vs. 46.0%, p=0.07). The rate of good outcome matches that of the EXTEND-IA trial that selected patients using perfusion imaging (68.2% vs. 71.0%, p = 1.00). None of the patients in our cohort had symptomatic intracereberal hemorrhage. Conclusion: Advanced MR imaging may help select patients with acute ischemic stroke and anterior circulation large vessel occlusion for embolectomy beyond the treatment window used in most endovascular trials.

scholarly journals The dynamic change of MR imaging in acute ischemic stroke with tPA therapy

Nosotchu ◽  
2017 ◽  
Vol 39 (6) ◽  
pp. 425-432
Author(s):  
Satoshi Tamura ◽  
Kazuhiro Ando ◽  
Nobuyuki Genkai ◽  
Kenichi Kakinuma
Keyword(s):  
Ischemic Stroke ◽  
Mr Imaging ◽  
Acute Ischemic Stroke ◽  
Dynamic Change

Diffusion MR imaging of acute ischemic stroke

2002 ◽  
Vol 12 (1) ◽  
pp. 35-53 ◽  
Author(s):  
Javier M Romero ◽  
Pamela W Schaefer ◽  
P.Ellen Grant ◽  
Lino Becerra ◽  
R.Gilberto González
Keyword(s):  
Ischemic Stroke ◽  
Mr Imaging ◽  
Acute Ischemic Stroke ◽  
Diffusion Mr ◽  
Diffusion Mr Imaging

Timely Visualization of the Collaterals Formed during Acute Ischemic Stroke with Fe3 O4 Nanoparticle-based MR Imaging Probe

Small ◽  
2018 ◽  
Vol 14 (23) ◽  
pp. 1800573 ◽  
Author(s):  
Ting Wang ◽  
Yi Hou ◽  
Bo Bu ◽  
Wenxin Wang ◽  
Tiancong Ma ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Mr Imaging ◽  
Acute Ischemic Stroke ◽  
Imaging Probe
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