ZnO Nanowire Arrays Exhibit Cytotoxic Distinction to Cancer Cells with Different Surface Charge Density: Cytotoxicity is Charge-Dependent

Small ◽  
2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Ruizhi Ning ◽  
Shiqi Wang ◽  
Jing Wu ◽  
Feng Wang ◽  
Jin-Ming Lin
Keyword(s):  
Charge Density ◽  
Surface Charge ◽  
Cancer Cells ◽  
Surface Charge Density ◽  
Nanowire Arrays ◽  
Zno Nanowire ◽  
Zno Nanowire Arrays

scholarly journals The Modulating Effect of p-Coumaric Acid on The Surface Charge Density of Human Glioblastoma Cell Membranes

2019 ◽  
Vol 20 (21) ◽  
pp. 5286 ◽  
Author(s):  
Marcin Andrzej Kruszewski ◽  
Joanna Kotyńska ◽  
Magdalena Kusaczuk ◽  
Miroslav Gál ◽  
Monika Naumowicz
Keyword(s):  
Charge Density ◽  
Surface Charge ◽  
Cancer Cells ◽  
Functional Groups ◽  
Surface Charge Density ◽  
Cell Membranes ◽  
Membrane Surface ◽  
Glioblastoma Cell ◽  
Coumaric Acid ◽  
Human Glioblastoma Cell

p-Coumaric acid (p-CoA), a phenolic acid belonging to the hydroxycinnamic acids family, is a compound with tentative anticancer potential. Microelectrophoretic mobility measurements conducted at various pH values of electrolyte solution were applied to study p-CoA effects on electrical properties of human glioblastoma cell membranes. The obtained results demonstrated that after the p-CoA treatment, the surface charge density of cancer cells changed in alkaline pH solutions, while no noticeable changes were observed in cell membranes incubated with p-CoA compared to control at acidic pH solutions. A four-equilibrium model was used to describe the phenomena occurring on the cell membrane surface. The total surface concentrations of both acidic and basic functional groups and their association constants with solution ions were calculated and used to define theoretical curves of membrane surface charge density versus pH. The resulting theoretical curves and the experimental data were compared to verify the reliability and validity of the adopted model. The deviation of both kinds of data obtained at a higher pH may be caused by disregarding interactions between the functional groups of cancer cells. Processes occurring in the cell membranes after their incubation with p-CoA can lead to disorders of existing equilibria, which result in changes in values of the parameters describing these equilibria.

Structure and Optical Properties of ZnO Nanowire Arrays Grown by Plasma-assisted Molecular Beam Epitaxy

2012 ◽  
Vol 27 (3) ◽  
pp. 301-304 ◽  
Author(s):  
Zhi-Yuan ZHENG ◽  
Tie-Xin CHEN ◽  
Liang CAO ◽  
Yu-Yan HAN ◽  
Fa-Qiang XU
Keyword(s):  
Optical Properties ◽  
Molecular Beam Epitaxy ◽  
Molecular Beam ◽  
Nanowire Arrays ◽  
Zno Nanowire ◽  
Zno Nanowire Arrays

scholarly journals Mapping Surface Charge Distribution of Single-Cell via Charged Nanoparticle

Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1519
Author(s):  
Leixin Ouyang ◽  
Rubia Shaik ◽  
Ruiting Xu ◽  
Ge Zhang ◽  
Jiang Zhe
Keyword(s):  
Cell Surface ◽  
Charge Density ◽  
Surface Charge ◽  
Charge Distribution ◽  
Surface Charge Density ◽  
Single Cells ◽  
Fluorescent Light ◽  
Fluorescent Nanoparticles ◽  
Cell Surface Charge ◽  
Surface Charge Distribution

Many bio-functions of cells can be regulated by their surface charge characteristics. Mapping surface charge density in a single cell’s surface is vital to advance the understanding of cell behaviors. This article demonstrates a method of cell surface charge mapping via electrostatic cell–nanoparticle (NP) interactions. Fluorescent nanoparticles (NPs) were used as the marker to investigate single cells’ surface charge distribution. The nanoparticles with opposite charges were electrostatically bonded to the cell surface; a stack of fluorescence distribution on a cell’s surface at a series of vertical distances was imaged and analyzed. By establishing a relationship between fluorescent light intensity and number of nanoparticles, cells’ surface charge distribution was quantified from the fluorescence distribution. Two types of cells, human umbilical vein endothelial cells (HUVECs) and HeLa cells, were tested. From the measured surface charge density of a group of single cells, the average zeta potentials of the two types of cells were obtained, which are in good agreement with the standard electrophoretic light scattering measurement. This method can be used for rapid surface charge mapping of single particles or cells, and can advance cell-surface-charge characterization applications in many biomedical fields.

Triboelectrification of nanocomposites using identical polymer matrixes with different concentrations of nanoparticle fillers

2021 ◽  
Author(s):  
Linards Lapčinskis ◽  
Artis Linarts ◽  
Kaspars Mālnieks ◽  
Hyunseung Kim ◽  
Kristaps Rubenis ◽  
...  
Keyword(s):  
Charge Density ◽  
Surface Charge ◽  
Surface Charge Density ◽  
Polymer Layers

In this study, we investigate triboelectrification in polymer-based nanocomposites using identical polymer matrixes containing different concentrations of nanoparticles (NPs). The triboelectric surface charge density on polymer layers increased as the...

scholarly journals Effect of Selected Anionic and Cationic Drugs Affecting the Central Nervous System on Electrical Properties of Phosphatidylcholine Liposomes: Experiment and Theory

2021 ◽  
Vol 22 (5) ◽  
pp. 2270
Author(s):  
Joanna Kotyńska ◽  
Monika Naumowicz
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Charge Density ◽  
Surface Charge ◽  
Surface Charge Density ◽  
Barbituric Acid ◽  
Membrane Surface ◽  
Adsorption Equilibria ◽  
Two Component ◽  
The Central Nervous System

Interactions between phospholipid membranes and selected drugs affecting the central nervous system (CNS) were investigated. Small, unilamellar liposomes were used as biomimetic cell membrane models. Microelectrophoretic experiments on two-component liposomes were performed using the electrophoretic light scattering technique (ELS). The effect of both positively (perphenazine, PF) and negatively (barbituric acid, BA) charged drugs on zwitterionic L-α-phosphatidylcholine (PC) membranes were analyzed. Experimental membrane surface charge density (d) data were determined as a function of pH. Quantitative descriptions of the adsorption equilibria formed due to the binding of solution ions to analyzed two-component membranes are presented. Binding constants of the solution ions with perphenazine and barbituric acid-modified membranes were determined. The results of our research show that both charged drugs change surface charge density values of phosphatidylcholine membranes. It can be concluded that perphenazine and barbituric acid are located near the membrane surface, interacting electrostatically with phosphatidylcholine polar heads.

Surface charging parameters of charged particles in symmetrical electrolyte solutions

2020 ◽  
Vol 22 (35) ◽  
pp. 20123-20142
Author(s):  
Hadi Saboorian-Jooybari ◽  
Zhangxin Chen
Keyword(s):  
Charge Density ◽  
Surface Charge ◽  
Electrolyte Solution ◽  
Surface Charge Density ◽  
Potential Surface ◽  
Research Work ◽  
Charged Particles ◽  
Electrolyte Solutions ◽  
Surface Charging ◽  
Curvature Dependence

This research work is directed at development of accurate physics-based formulas for quantification of curvature-dependence of surface potential, surface charge density, and total surface charge for cylindrical and spherical charged particles immersed in a symmetrical electrolyte solution.

A multi-dielectric-layered triboelectric nanogenerator as energized by corona discharge

Nanoscale ◽  
2017 ◽  
Vol 9 (27) ◽  
pp. 9668-9675 ◽  
Author(s):  
Jia Jia Shao ◽  
Wei Tang ◽  
Tao Jiang ◽  
Xiang Yu Chen ◽  
Liang Xu ◽  
...  
Keyword(s):  
Charge Density ◽  
Surface Charge ◽  
Corona Discharge ◽  
Surface Charge Density ◽  
High Surface ◽  
Cycling Stability ◽  
Triboelectric Nanogenerator ◽  
Excellent Cycling Stability ◽  
Vertical Contact ◽  
High Surface Charge Density

A multi-dielectric-layered vertical contact-separation mode TENG through a corona discharge approach results in outstanding output performances, i.e., a high surface charge density of 283 μC m−2 and excellent cycling stability (92.6% retention after 200 000 cycles).

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