Iron Oxide Nanoparticles: Chemical Design of Biocompatible Iron Oxide Nanoparticles for Medical Applications (Small 9-10/2013)

Small ◽  
2013 ◽  
Vol 9 (9-10) ◽  
pp. 1449-1449 ◽  
Author(s):  
Daishun Ling ◽  
Taeghwan Hyeon
2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Madhu Bala Sathyanarayanan ◽  
Reneta Balachandranath ◽  
Yuvasri Genji Srinivasulu ◽  
Sathish Kumar Kannaiyan ◽  
Guruprakash Subbiahdoss

Microbial biofilms on biomaterial implants or devices are hard to eliminate by antibiotics due to their protection by exopolymeric substances that embed the organisms in a matrix, impenetrable for most antibiotics and immune-cells. Application of metals in their nanoparticulated form is currently considered to resolve bacterial infections. Gold and iron-oxide nanoparticles are widely used in different medical applications, but their utilisation to eradicate biofilms on biomaterials implants is novel. Here, we studied the effect of gold and iron oxide nanoparticles on Staphylococcus aureus and Pseudomonas aeruginosa biofilms. We report that biofilm growth was reduced at higher concentrations of gold and iron-oxide nanoparticles compared to absence of nanoparticles. Thus nanoparticles with appropriate concentration could show significant reduction in biofilm formation.


2018 ◽  
Vol 9 ◽  
pp. 2413-2420 ◽  
Author(s):  
Christian D Ahrberg ◽  
Ji Wook Choi ◽  
Bong Geun Chung

Nanoparticles have gained large interest in a number of different fields due to their unique properties. In medical applications, for example, magnetic nanoparticles can be used for targeting, imaging, magnetically induced thermotherapy, or for any combination of the three. However, it is still a challenge to obtain narrowly dispersed, reproducible particles through a typical lab-scale synthesis when researching these materials. Here, we present a droplet capillary reactor that can be used for the synthesis of magnetic iron oxide nanoparticles. Compared to conventional batch synthesis, the particles synthesized in our droplet reactor have a narrower size distribution and a higher reproducibility. Furthermore, we demonstrate how the particle size can be changed from 5.2 ± 0.9 nm to 11.8 ± 1.7 nm by changing the reaction temperature and droplet residence time in the droplet capillary reactor.


Iron Oxides ◽  
2016 ◽  
pp. 425-472 ◽  
Author(s):  
Amanda K. Andriola Silva ◽  
Ana Espinosa ◽  
Jelena Kolosnjaj‐Tabi ◽  
Claire Wilhelm ◽  
Florence Gazeau

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