Post-traumatic Stress Disorder, Anxiety and Depression among the Elderly: A Survey of the Hard-hit Areas a Year after the Wenchuan Earthquake

2011 ◽  
Vol 28 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Zhen Zhang ◽  
Zhanbiao Shi ◽  
Li Wang ◽  
Mingxin Liu
Keyword(s):  
Wenchuan Earthquake ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
The Elderly ◽  
Anxiety And Depression ◽  
Post Traumatic Stress ◽  
The Wenchuan Earthquake ◽  
Post Traumatic

Prevalence of post-traumatic stress disorder among adolescents after the Wenchuan earthquake in China

2011 ◽  
Vol 42 (8) ◽  
pp. 1687-1693 ◽  
Author(s):  
Z. Zhang ◽  
M.-S. Ran ◽  
Y.-H. Li ◽  
G.-J. Ou ◽  
R.-R. Gong ◽  
...  
Keyword(s):  
Wenchuan Earthquake ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Depression Symptoms ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
The Wenchuan Earthquake ◽  
Post Traumatic

BackgroundThe Wenchuan earthquake was a catastrophic earthquake in China. The aim of this study is to explore longitudinally the rates of post-traumatic stress disorder (PTSD) and depression in adolescents after the Wenchuan earthquake, and to identify independent predictors of PTSD.MethodPTSD and depression symptoms among adolescents at 6, 12 and 18 months after the Wenchuan earthquake were investigated using the PTSD Checklist Civilian Version and the Beck Depression Inventory (BDI). Subjects in this study included 548 high school student survivors in a local boarding high school.ResultsThe rates of PTSD symptoms were 9.7%, 1.3% and 1.6% at the 6-, 12- and 18-month follow-ups, respectively. BDI scores were found to be the best predictor of severity of PTSD at 6, 12 and 18 months. Gender was another variable contributing significantly to PTSD at 6 and 12 months after the earthquake. In the 12-month follow-up, home damage was found to be a predictor of severity of PTSD symptoms. Being a child with siblings was found to be a predictor of severity of PTSD symptoms at 12 and 18 months after the earthquake.ConclusionsPTSD symptoms changed gradually at various stages after the earthquake. Depression symptoms were predictive of PTSD symptoms in the 18-month follow-up study. Other predictors of PTSD symptoms included female gender and being a child with siblings. The results of this study may be helpful for further mental health interventions for adolescents after earthquakes.

Silymarin Prevents Memory Impairments, Anxiety, and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder

Planta Medica ◽  
2018 ◽  
Vol 85 (01) ◽  
pp. 32-40 ◽  
Author(s):  
Tamam El-Elimat ◽  
Karem Alzoubi ◽  
Mahmoud AbuAlSamen ◽  
Zeinab Al Subeh ◽  
Tyler Graf ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Anxiety And Depression ◽  
Long Term Memory ◽  
Post Traumatic Stress ◽  
Term Memory ◽  
Memory Impairments ◽  
Post Traumatic

AbstractPost-traumatic stress disorder (PTSD) is a debilitating psychopathological disease that is triggered by exposure to traumatic events. It is usually associated with substantial comorbidities, such as cognitive impairment, anxiety, and depression. Silymarin has been recently reported to exert neuroprotective activities against neurodegenerative diseases such as Alzheimerʼs and Parkinsonʼs diseases. Herein, the beneficial effects of silymarin in ameliorating PTSD-like symptoms such as memory impairments, anxiety, and depression were evaluated using a single-prolonged stress (SPS) rat model of PTSD. Male Wistar rats were randomly assigned into four groups: control, silymarin, SPS, or SPS + silymarin. Rats were administrated silymarin, 100 mg/kg i. p. for 4 wk. Rats in all groups were tested for short- and long-term memory in the radial arm water maze (RAWM), for anxiety-like behaviors using the open field test (OFT) and elevated plus maze (EPM) test, and for depression-like symptoms using the tail suspension test (TST). Conventional analyses of the RAWM, EPM, OFT, and TST were conducted using analysis of variance. Additionally, the anxiety-related behavior parameters of the EPM and OFT were entered to principal component analysis. Regression scores based on the first two extracted components, which accounted for 61% of the variance, were indicative of the anxiolytic activity of silymarin. Collectively, the results suggest that silymarin treatment prevents SPS-induced long-term memory impairments, anxiety, and depressive-like symptoms in rat models.

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