Ultrasonic‐Assisted Ionic Liquid Extraction of Four Biflavonoids from Ginkgo biloba L .

2021 ◽  
Vol 6 (14) ◽  
pp. 3297-3307
Author(s):  
Jie Lei ◽  
Yongmei Jiang ◽  
Xirong Luo ◽  
Yu Zheng ◽  
Lei Zhu ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ginkgo Biloba ◽  
Liquid Extraction ◽  
Ultrasonic Assisted

scholarly journals Correction to Ultrasonic-Assisted Ionic Liquid Extraction of Two Biflavonoids from Selaginella tamariscina

ACS Omega ◽  
2021 ◽  
Vol 6 (15) ◽  
pp. 10505-10505
Author(s):  
Yongmei Jiang ◽  
Sen Wang ◽  
Ming Yu ◽  
Di wu ◽  
Jie Lei ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Extraction ◽  
Ultrasonic Assisted ◽  
Selaginella Tamariscina

scholarly journals Ultrasonic-Assisted Ionic Liquid Extraction of Two Biflavonoids from Selaginella tamariscina

ACS Omega ◽  
2020 ◽  
Vol 5 (51) ◽  
pp. 33113-33124
Author(s):  
Yongmei Jiang ◽  
Sen Wang ◽  
Ming Yu ◽  
Di Wu ◽  
Jie Lei ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Extraction ◽  
Ultrasonic Assisted ◽  
Selaginella Tamariscina

Ionic liquid extraction of silkworm pupa protein and its biological characteristics

2021 ◽  
Author(s):  
Qing-Lei Zeng ◽  
Ning Zhang ◽  
Yue-Yue Zhang ◽  
Xiang-Dong Xin ◽  
Thomas Attaribo ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Liquid Extraction ◽  
Biological Characteristics ◽  
Silkworm Pupa

scholarly journals Development of trace analysis for alkyl methanesulfonates in the delgocitinib drug substance using GC-FID and liquid–liquid extraction with ionic liquid

2020 ◽  
Vol 18 (1) ◽  
pp. 1020-1029
Author(s):  
Shinkichi Nomura ◽  
Yoshiharu Ito ◽  
Shigehiko Takegami ◽  
Tatsuya Kitade
Keyword(s):  
Ionic Liquid ◽  
Trace Analysis ◽  
Direct Injection ◽  
Liquid Extraction ◽  
Drug Substance ◽  
Flame Ionization ◽  
Liquid Liquid Extraction ◽  
Accuracy And Precision ◽  
Sensitivity And Selectivity ◽  
Chloride Water

AbstractAlkyl methanesulfonates are genotoxic impurities that should be limited to an intake of not more than 1.5 µg/day, as regulated by the International Council for Harmonization guideline M7. We herein report a trace analysis of methyl methanesulfonate (MMS), ethyl methanesulfonate (EMS), and isopropyl methanesulfonate (IPMS) in the delgocitinib drug substance using liquid–liquid extraction, with an ionic liquid as the sample-solving medium, and direct injection gas chromatography detected with a flame-ionization detector. The proposed method takes advantage of the fine solubility of ionic liquids toward the drug substance, the good extraction efficiency of alkyl methanesulfonates in liquid–liquid extraction using the Chem Elut cartridge with low-polar organic solvents, and the ability of alkyl methanesulfonates to concentrate in minimum amounts of organic solvent, resulting in excellent sensitivity and selectivity. Specifically, for the preparation of the sample solution, a mixture of 1-butyl-3-methylimidazolium chloride, water, and acetonitrile was used as the sample-solving media, extracted with diethyl ether, and the eluent was concentrated to 1 mL. The method showed good linearity, accuracy, and precision from 1 to 5 ppm, and the limits of detection of MMS, EMS, and IPMS were 0.1, 0.05, and 0.05 ppm, respectively.

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