scholarly journals Approach to Artificial Nucleosides from Glycoside Isothiocyanates: Synthesis of Original N‐Glycosylated Heterostructures by Cyclocondensation Reactions

2019 ◽  
Vol 4 (42) ◽  
pp. 12232-12235
Author(s):  
Sylvain Grosjean ◽  
Karine Julienne ◽  
Sébastien G. Gouin ◽  
David Deniaud
Keyword(s):  
Cyclocondensation Reactions

Regioselective Synthesis of Pyrazolyl-pyrimidine Hybrids of Pharmacological Interest

Synthesis ◽  
2020 ◽  
Vol 52 (16) ◽  
pp. 2347-2356 ◽  
Author(s):  
Nilo Zanatta ◽  
Adriano F. Camargo ◽  
Mário A. Marangoni ◽  
Paulo A. de Moraes ◽  
Pablo A. Nogara ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Regioselective Synthesis ◽  
Pharmacological Interest ◽  
Cyclocondensation Reactions

The regioselective synthesis of twenty novel [3-substituted 5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl][6-aryl-(2-methylthio)pyrimidin-4-yl]methanones from the cyclocondensation reactions of new 6-aryl-2-(methylthio)pyrimidine-4-carbohydrazides with 4-substituted 1,1,1-trifluorobut-3-en-2-ones is reported. Human acetylcholinesterase (HsAChE) and butyrylcholinesterase (HsBChE) inhibition tests were performed on selected products in order to explore the possible pharmacological applications of these compounds. Two compounds showed significant and selective inhibitory activity for BChE.

ChemInform Abstract: Enantio- and Diastereoconvergent Cyclocondensation Reactions: Synthesis of Enantiopure cis-Decahydroquinolines.

ChemInform ◽  
2014 ◽  
Vol 45 (18) ◽  
pp. no-no
Author(s):  
Mercedes Amat ◽  
Elena Ghirardi ◽  
Laura Navio ◽  
Rosa Griera ◽  
Nuria Llor ◽  
...  
Keyword(s):  
Cyclocondensation Reactions

ChemInform Abstract: Methyl 3,3,3-Trifluoro-2-(thiazol-2-ylimino)propionate in Cycloaddition and Cyclocondensation Reactions.

ChemInform ◽  
2014 ◽  
Vol 45 (3) ◽  
pp. no-no
Author(s):  
V. B. Sokolov ◽  
A. Yu. Aksinenko ◽  
T. A. Epishina ◽  
T. V. Goreva
Keyword(s):  
Cyclocondensation Reactions

ChemInform Abstract: Methyl Trifluoropyruvate N-(Pyrimidin-2-yl)imines in Cyclocondensation Reactions with 1,3-Binucleophilic Reagents.

ChemInform ◽  
2013 ◽  
Vol 44 (49) ◽  
pp. no-no
Author(s):  
V. B. Sokolov ◽  
A. Yu. Aksinenko ◽  
T. A. Epishina ◽  
T. V. Goreva
Keyword(s):  
Methyl Trifluoropyruvate ◽  
Cyclocondensation Reactions
Sign in / Sign up

Export Citation Format

Share Document