An Overview of Recent Advances in the Applications of Click Chemistry in the Synthesis of Bioconjugates with Anticancer Activities

2019 ◽  
Vol 4 (46) ◽  
pp. 13459-13478 ◽  
Author(s):  
Koroush Mashayekh ◽  
Pezhman Shiri
Keyword(s):  
Click Chemistry ◽  
Anticancer Activities ◽  
Recent Advances

Synthesis, optical properties, and antioxidant and anticancer activity of benzoheterazole dendrimers with triazole bridging unit

2018 ◽  
Vol 42 (5) ◽  
pp. 3282-3292 ◽  
Author(s):  
Kannan Rajavelu ◽  
Mamangam Subaraja ◽  
Perumal Rajakumar
Keyword(s):  
Optical Properties ◽  
Bisphenol A ◽  
Anticancer Activity ◽  
Click Chemistry ◽  
Anticancer Activities

Benzoheterazole dendrimers with triazole bridges and bisphenol A/benzophenone core units have been successfully synthesized by click chemistry. Higher generation dendrimers exhibit better antioxidant and anticancer activities than the lower generation dendrimers.

scholarly journals Boronic acid based dynamic click chemistry: recent advances and emergent applications

2021 ◽  
Author(s):  
Saurav Chatterjee ◽  
Eric V. Anslyn ◽  
Anupam Bandyopadhyay
Keyword(s):  
Click Chemistry ◽  
Boronic Acid ◽  
Recent Advances

Fundamental progress, current developments, and rapidly growing applications of iminoboronate and salicylhydroxamic–boronate conjugate esters are deliberated.

Synthesis, characterization, optical and electrochemical properties and antifungal and anticancer activities of ferrocenyl conjugated novel dendrimers

2017 ◽  
Vol 41 (4) ◽  
pp. 1714-1722 ◽  
Author(s):  
Velautham Saravanan ◽  
Ayyavoo Kannan ◽  
Perumal Rajakumar
Keyword(s):  
Antifungal Activity ◽  
Electrochemical Properties ◽  
Anticancer Activity ◽  
Click Chemistry ◽  
Fungal Pathogens ◽  
Anticancer Activities ◽  
New Class ◽  
Mcf 7

A new class of triazoloferrocenyl conjugates was prepared by copper(i) catalyzed click chemistry, which shows good antifungal activity against fungal pathogens, and also shows excellent anticancer activity against MCF-7 cells.

New click-chemistry methods for 1,2,3-triazoles synthesis: recent advances and applications

2015 ◽  
Vol 56 (22) ◽  
pp. 2853-2859 ◽  
Author(s):  
Jane Totobenazara ◽  
Anthony J. Burke
Keyword(s):  
Click Chemistry ◽  
Recent Advances

Photophysical and Electrochemical Properties and Anticancer Activities of Porphyrin-Cored Fluorenodendrimers Synthesized by Click Chemistry

Synlett ◽  
2018 ◽  
Vol 29 (15) ◽  
pp. 1995-2000
Author(s):  
Perumal Rajakumar ◽  
Devaraj Anandkumar
Keyword(s):  
Click Chemistry ◽  
Bathochromic Shift ◽  
13C Nmr Spectroscopy ◽  
Oxidation Potential ◽  
Anticancer Activities ◽  
New Class ◽  
Vis Spectroscopy ◽  
Dendrimer Generation ◽  
Convergent Approach ◽  
First And Second Generation

A new class of porphyrin-cored fluorenodendrimers were synthesized by a convergent approach through click chemistry. The zeroth-, first-, and second-generation porphyrin-cored fluorenodendrimers were characterized by means of 1H and 13C NMR spectroscopy, UV-vis spectroscopy, fluorescent spectroscopy, elemental analysis, and MALDI-TOF mass spectrometry. The UV-vis spectrum of the dendrimers showed an increase in the absorption intensity on increasing the dendrimer generation, and a bathochromic shift was observed for higher-generation dendrimers compared with lower-generation dendrimers. The dendrimers showed emission bands at 317, 604–668, and 617–668 nm, the intensity of which increased with increasing dendrimer generation. All the synthesized dendrimers exhibited a reversible oxidation potential in cyclic voltammetry. The therapeutic efficacy of the porphyrin-cored fluorenodendrimers for the inhibition of a growth tumor cell (PA-1) increased with increasing generation number of the dendrimer.

Recent advances towards sulfur (VI) fluoride exchange (SuFEx) click chemistry

2018 ◽  
Vol 213 ◽  
pp. 87-112 ◽  
Author(s):  
Tanzeela Abdul Fattah ◽  
Aamer Saeed ◽  
Fernando Albericio
Keyword(s):  
Click Chemistry ◽  
Recent Advances
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