In Vitro Investigation of Controlled Release of Ciprofloxacin and Its β ‐Cyclodextrin Inclusion Complex from Gelatin Grafted Poly(vinyl alcohol) (GPVA) Nanoparticles

2019 ◽  
Vol 4 (38) ◽  
pp. 11337-11345
Author(s):  
Archana G. Tanwar ◽  
Pranjali B. Date ◽  
Divya P. Ottoor
Keyword(s):  
Controlled Release ◽  
Inclusion Complex ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Cyclodextrin Inclusion ◽  
In Vitro Investigation ◽  
Cyclodextrin Inclusion Complex

BEHAVIOURAL STUDY OF CYCLODEXTRIN INCLUSION COMPLEX ON ENHANCEMENT OF SOLUBILITY OF ACECLOFENAC

INDIAN DRUGS ◽  
2015 ◽  
Vol 52 (11) ◽  
pp. 19-23
Author(s):  
J Shaikh ◽  
◽  
S. V. Deshmane ◽  
R. N Purohit ◽  
K. R. Biyani
Keyword(s):  
Inclusion Complex ◽  
Solid Dispersion ◽  
Water Soluble ◽  
In Vitro Dissolution ◽  
Phase Solubility ◽  
Solubility Study ◽  
Cyclodextrin Inclusion ◽  
Poorly Water Soluble ◽  
Cyclodextrin Inclusion Complex

The main objective of the present study was to enhance the solubility and dissolution rate of poorly water soluble aceclofenac using its solid dispersion with β-cyclodextrin. FTIR and DSC study was carried out to find out any incompatibility. The phase solubility of drug was carried out in 1, 2, 5, and 10% of β-cyclodextrin in distilled water. Kneading method and solvent evaporation method was use to prepared solid dispersion of aceclofenac and β-cyclodextrin. Different evaluation tests like solubility study in different solvents, PXRD and in vitro dissolution study of aceclofenac- β-cyclodextrin inclusion complex were carried out. The overall finding indicated that β-cyclodextrin is a desirable water soluble carrier, that helps in increasing solubility of drug. Due to its structural feature, β-cyclodextrin forms a good inclusion complex that decreases contact angle of drug with water molecules by increasing wetting properties. Hence, it can be concluded that, β-cyclodextrin is better water soluble carrier molecule in terms of its compatibility and increasing solubility behavior of poorly water soluble drug aceclofenac.

scholarly journals Delineating the behavior of Berberis anthocyanin/β-cyclodextrin inclusion complex in vitro: A molecular dynamics approach

LWT ◽  
2022 ◽  
pp. 113090
Author(s):  
Prakash Chandra Pradhan ◽  
Abhishek Mandal ◽  
Anirban Dutta ◽  
Rohan Sarkar ◽  
Aditi Kundu ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Inclusion Complex ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex

Characterization of a new TiF4 and β-cyclodextrin inclusion complex and its in vitro evaluation on inhibiting enamel demineralization

2013 ◽  
Vol 58 (3) ◽  
pp. 239-247 ◽  
Author(s):  
Camila Nassur ◽  
Adílis Kalina Alexandria ◽  
Luciana Pomarico ◽  
Valeria Pereira de Sousa ◽  
Lúcio Mendes Cabral ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
In Vitro Evaluation ◽  
Enamel Demineralization ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex

Preparation of celecoxib-dimethyl-β-cyclodextrin inclusion complex: characterization and in vitro permeation study

2005 ◽  
Vol 40 (7) ◽  
pp. 624-631 ◽  
Author(s):  
Cinzia Anna Ventura ◽  
Ignazio Giannone ◽  
Donatella Paolino ◽  
Venerando Pistarà ◽  
Antonino Corsaro ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Cyclodextrin Inclusion ◽  
Permeation Study ◽  
In Vitro Permeation ◽  
Complex Characterization ◽  
Cyclodextrin Inclusion Complex
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