A regioselective Synthesis of Substituted Pyrazolines via a Cascade Annulation of Huisgen Zwitterion with α‐Cyano‐α,β‐unsaturated Ketones Under Solvent‐free Heating Conditions

2019 ◽  
Vol 4 (35) ◽  
pp. 10352-10356
Author(s):  
Yuming Li ◽  
Xuange Zhang ◽  
Tianyu Lu ◽  
Zhiwei Miao
Keyword(s):  
Solvent Free ◽  
Regioselective Synthesis ◽  
Unsaturated Ketones

One-pot Synthesis of α,β-Unsaturated Ketones through Sequential Alkyne Dimerization/Hydration Reactions using Hoveyda-Grubbs Catalyst

2021 ◽  
Author(s):  
Bengi Öztürk ◽  
Begüm Sarıaslan ◽  
Mina Aşkun ◽  
Zeynep Tunalı ◽  
Solmaz Karabulut
Keyword(s):  
Regioselective Synthesis ◽  
Grubbs Catalyst ◽  
One Pot ◽  
Unsaturated Ketones ◽  
One Pot Synthesis

Herein we report a sequential one-pot alkyne dimerization/hydration protocol for the regioselective synthesis of α,β-unsaturated ketones in quantitive yields. The alkyne dimerization reactions of terminal arylacetylenes proceeded with high regioselectivity...

Simple Access to α, β Unsaturated Ketones by Acid-Catalyzed Solvent-Free Reactions

1999 ◽  
Vol 29 (20) ◽  
pp. 3651-3657 ◽  
Author(s):  
Erwan Le Gall ◽  
Françoise Texier-Boullet ◽  
Jack Hamelin
Keyword(s):  
Solvent Free ◽  
Unsaturated Ketones ◽  
Acid Catalyzed

Highly efficient regioselective synthesis of pyrroles via a tandem enamine formation–Michael addition–cyclization sequence under catalyst- and solvent-free conditions

2015 ◽  
Vol 17 (6) ◽  
pp. 3415-3423 ◽  
Author(s):  
Thavaraj Vivekanand ◽  
Perumal Vinoth ◽  
B. Agieshkumar ◽  
Natarajan Sampath ◽  
Arumugam Sudalai ◽  
...  
Keyword(s):  
Column Chromatography ◽  
Michael Addition ◽  
Solvent Free ◽  
Regioselective Synthesis ◽  
Highly Efficient ◽  
Solvent Free Conditions ◽  
Enamine Formation

An efficient three-component, catalyst-, solvent-, and column chromatography-free procedure was developed for the synthesis of 3-(1H-pyrrol-3-yl)indolin-2-ones.

Regioselective Synthesis of 5H-Thiazolo[3,2-a]pyrimidin-5-ones from Morita-Baylis-Hillman Adduct Acetates under Solvent-Free and Base-Free Conditions

Synthesis ◽  
2009 ◽  
Vol 2009 (10) ◽  
pp. 1615-1622 ◽  
Author(s):  
Weike Su ◽  
Weihui Zhong ◽  
Baoming Guo ◽  
Fuliang Lin ◽  
Yongliang Liu
Keyword(s):  
Solvent Free ◽  
Regioselective Synthesis

Regioselective Synthesis of Isomeric 3-[1-Substituted Pyrazol-3(5)-yl]indoles from β-Ethylthio-β-indolyl-α,β-unsaturated Ketones

Synthesis ◽  
2020 ◽  
Vol 52 (14) ◽  
pp. 2111-2120
Author(s):  
Zemin Mei ◽  
Haifeng Yu ◽  
Peiqiu Liao
Keyword(s):  
Regioselective Synthesis ◽  
Unsaturated Ketones ◽  
Cyclocondensation Reaction

An efficient and highly regioselective synthesis of isomeric 3-[1-substituted pyrazol-3(5)-yl]indoles has been developed by the acid-mediated regioselective cyclocondensation reaction of β-ethyltho-β-indolyl-α,β-unsaturated ketones and monosubstituted hydrazines. In the presence of 1 equivalent of AcOH in refluxing EtOH, the cyclocondensation reaction of β-ethyltho-β- indolyl-α,β-unsaturated ketones with monosubstituted hydrazines yielded 3-(1-substituted pyrazol-5-yl)indoles in excellent yields, while 3-(1-substituted pyrazol-3-yl)indoles were obtained in good yields when the cyclocondensation reaction was carried out in refluxing AcOH.

The Iron(III) Chloride Mediated 1,4-Addition of Mercaptans to α,β-Unsaturated Ketones and Esters under Solvent-Free Conditions.

ChemInform ◽  
2007 ◽  
Vol 38 (1) ◽  
Author(s):  
Cheng-Ming Chu ◽  
Wan-Ju Huang ◽  
Chaowei Lu ◽  
Pohsi Wu ◽  
Ju-Tsung Liu ◽  
...  
Keyword(s):  
Solvent Free ◽  
Unsaturated Ketones ◽  
Solvent Free Conditions
Sign in / Sign up

Export Citation Format

Share Document