Green Approach for the Domino Reduction/Reductive Amination of Nitroarenes and Chemoselective Reduction of Aldehydes Using Fe/aq. Citric Acid/Montmorillonite K10

2018 ◽  
Vol 3 (48) ◽  
pp. 13670-13674
Author(s):  
Koti Siva Nagi Reddy ◽  
Karra Purushotham Reddy ◽  
Gowravaram Sabitha
Keyword(s):  
Citric Acid ◽  
Reductive Amination ◽  
Montmorillonite K10 ◽  
Green Approach

ChemInform Abstract: Green Approach for the Efficient Synthesis of Quinolines Promoted by Citric Acid.

ChemInform ◽  
2009 ◽  
Vol 40 (7) ◽  
Author(s):  
Ramu Enugala ◽  
Sreelatha Nuvvula ◽  
Vijay Kotra ◽  
Ravi Varala ◽  
Srinivas R. Adapa
Keyword(s):  
Citric Acid ◽  
Efficient Synthesis ◽  
Green Approach

Green Approach for the Efficient Synthesis of Quinolines Promoted by Citric Acid

Heterocycles ◽  
2008 ◽  
Vol 75 (10) ◽  
pp. 2523 ◽  
Author(s):  
Srinivas R. Adapa ◽  
Ramu Enugala ◽  
Sreelatha Nuvvula ◽  
Vijay Kotra ◽  
Ravi Varala ◽  
...  
Keyword(s):  
Citric Acid ◽  
Efficient Synthesis ◽  
Green Approach

Coadministration of citric acid allows oxytetracycline dose reduction in yellowtail Seriola quinqueradiata infected with Vibrio anguillarum

2020 ◽  
Vol 140 ◽  
pp. 25-29
Author(s):  
K Akiyama ◽  
N Hirazawa ◽  
A Hatanaka
Keyword(s):  
Body Weight ◽  
Citric Acid ◽  
Effective Treatment ◽  
Dose Reduction ◽  
Vibrio Anguillarum ◽  
Enhancing Effect ◽  
Bacterial Diseases ◽  
Seriola Quinqueradiata ◽  
Poor Efficacy

Oxytetracycline (OTC) has been commonly used as an effective antibiotic against various fish bacterial diseases, including vibriosis. In this study, the absorption-enhancing effect of citric acid on oral OTC pharmacokinetics and treatment of artificial Vibrio anguillarum infection was evaluated in juvenile yellowtail Seriola quinqueradiata followed by serum OTC concentration analysis. When 25 mg kg-1 body weight (BW) OTC was administered in combination with 1250 mg kg-1 BW citric acid, the serum OTC concentration reached almost the same concentration as that of the group treated with 50 mg kg-1 BW OTC. This coadministration successfully suppressed mortality due to vibriosis similar to the group treated with 50 mg kg-1 BW OTC. Conversely, poor efficacy was observed when only 25 mg kg-1 BW OTC was administered. These results suggest that coadministration of citric acid can be beneficial in reducing the dose of OTC needed for effective treatment, and thus contributes to the goal of reduced use of this antibiotic in aquaculture.

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