Green Synthesis and Theoretical Study of β-Amino Esters via PPh3 -Catalyzed Mannich Reaction

2018 ◽  
Vol 3 (31) ◽  
pp. 8787-8792 ◽  
Author(s):  
Mustafa Hussain ◽  
Jianhui Liu ◽  
Zhipeng Zhang ◽  
Mengwei Hu ◽  
Yang Li ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Mannich Reaction ◽  
Theoretical Study ◽  
Amino Esters

scholarly journals Asymmetric tandem hemiaminal-heterocyclization-aza-Mannich reaction of 2-formylbenzonitriles and amines using chiral phase transfer catalysis: an experimental and theoretical study

RSC Advances ◽  
2016 ◽  
Vol 6 (38) ◽  
pp. 31861-31870 ◽  
Author(s):  
Amedeo Capobianco ◽  
Antonia Di Mola ◽  
Valentina Intintoli ◽  
Antonio Massa ◽  
Vito Capaccio ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Mannich Reaction ◽  
Phase Transfer Catalysis ◽  
Theoretical Study ◽  
Phase Transfer ◽  
Chiral Phase

The first asymmetric synthesis of 3-amino-substituted isoindolinones was accomplished via cascade hemiaminal-heterocyclization-intramolecular aza-Mannich reaction of amines and 2-formylbenzonitriles using chiral phase transfer conditions (PTC).

Theoretical Study of the Borono–Mannich Reaction with Pinacol Allenylboronate

2020 ◽  
Vol 85 (11) ◽  
pp. 7494-7500
Author(s):  
Sebastián O. Simonetti ◽  
Silvina C. Pellegrinet
Keyword(s):  
Mannich Reaction ◽  
Theoretical Study

Combined green synthesis and theoretical study of Ag/Co nanoparticles from biomass materials

2019 ◽  
Vol 125 (9) ◽  
Author(s):  
Anuoluwa Abimbola Akinsiku ◽  
Kolawole Oluseyi Ajanaku ◽  
Joseph Adeyemi Adekoya ◽  
Samuel Oluwakayode Ajayi ◽  
Moses Eterigho Emetere ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Theoretical Study ◽  
Biomass Materials ◽  
Co Nanoparticles

Chiral cinchona alkaloid-derived thiourea catalyst for enantioselective synthesis of novel β-amino esters by mannich reaction

Chirality ◽  
2012 ◽  
Vol 24 (3) ◽  
pp. 223-231 ◽  
Author(s):  
Weihua Li ◽  
Baoan Song ◽  
Pinaki S. Bhadury ◽  
Liang Li ◽  
Zhenchao Wang ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Enantioselective Synthesis ◽  
Cinchona Alkaloid ◽  
Amino Esters

A theoretical study of the nornicotine-catalyzed Mannich reaction in wet solvents and water

2014 ◽  
Vol 16 (8) ◽  
pp. 3999-4008 ◽  
Author(s):  
Sheng-Che Yang ◽  
Timm Lankau ◽  
Chin-Hui Yu
Keyword(s):  
Mannich Reaction ◽  
Theoretical Study ◽  
Quantum Calculations ◽  
Reaction In Water ◽  
The Way

Quantum calculations lead the way to a green version of the versatile Mannich reaction in water catalysed by nornicotine.

Theoretical Study on the Mechanism of Robinson's Synthesis of Tropinone

2003 ◽  
Vol 2003 (9) ◽  
pp. 580-583 ◽  
Author(s):  
Nityagopal Mondal ◽  
Sannyasi Charan Mandal ◽  
Gourab Kanti Das ◽  
Sarbananda Mukherjee
Keyword(s):  
Ab Initio ◽  
Mannich Reaction ◽  
Theoretical Study ◽  
Bond Formation ◽  
Quantum Mechanical Calculation ◽  
Quantum Mechanical ◽  
Carbon Bond ◽  
Mechanical Calculation ◽  
Carbon Carbon Bond ◽  
Water Elimination

Ab initio quantum mechanical calculation reveals that the first Mannich reaction in Robinson's tropinone synthesis involves both carbon–carbon bond formation and water elimination, which is followed by tautomerisation and a second Mannich reaction to form the protonated tropinone.

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