New Water‐Soluble N‐Heterocyclic Carbene‐Palladium Complexes as Promising Anti‐Tumor Agents: Investigating DNA and Protein Interactions

2018 ◽  
Vol 3 (21) ◽  
pp. 5709-5716 ◽  
Author(s):  
Prachi S. Bangde ◽  
Dharmendra S. Prajapati ◽  
Prajakta P. Dandekar ◽  
Anant R. Kapdi
Keyword(s):  
Protein Interactions ◽  
Palladium Complexes ◽  
Water Soluble

Pigment−Pigment and Pigment−Protein Interactions in Recombinant Water-Soluble Chlorophyll Proteins (WSCP) from Cauliflower

2007 ◽  
Vol 111 (46) ◽  
pp. 13325-13335 ◽  
Author(s):  
C. Theiss ◽  
I. Trostmann ◽  
S. Andree ◽  
F. J. Schmitt ◽  
T. Renger ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Water Soluble

Solubility and activity of a phosphinosulfonate palladium catalyst in water with different surfactants

2019 ◽  
Vol 10 (16) ◽  
pp. 1988-1992 ◽  
Author(s):  
Camille Boucher-Jacobs ◽  
Bo Li ◽  
Charles M. Schroeder ◽  
Damien Guironnet
Keyword(s):  
Palladium Catalyst ◽  
Palladium Complexes ◽  
Metal Center ◽  
Water Soluble

Water-soluble phosphinosulfonate palladium complexes were synthesized by coordination of a surfactant to the metal center.

scholarly journals New Di- and Triorganotin(IV) Tyrosylalaninates as Models for Metal—Protein Interactions: Synthesis, Structural Characterization, and Potentiometric Studies of Tyrosylalanine, Glycyltyrosine, and Glycylisoleucine with Di- and Trimethyltin(IV) Moieties in Aqueous Medium

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
Mala Nath ◽  
Sulaxna ◽  
Xueqing Song ◽  
George Eng
Keyword(s):  
Protein Interactions ◽  
Water Soluble ◽  
Tridentate Ligand ◽  
Spectroscopic Techniques ◽  
Complex Species ◽  
Carboxylate Oxygen ◽  
Trigonal Bipyramidal ◽  
Bipyramidal Structure ◽  
Ft Ir ◽  
Ph Range

Di- and triorganotin(IV) derivatives of tyrosylalanine (H2Tyr-Ala) with general formula R2Sn(Tyr-Ala) (where R = Me, n-Bu, n-Oct, and Ph) and R3Sn(HTyr-Ala) (where R = Me and Ph) have been synthesized and structurally characterized in the solid state as well as in solution on the basis of various spectroscopic techniques, namely. FT-IR, multinuclear (1H, 13C and 119Sn) NMR and 119Sn Mössbauer. These investigations suggest that tyrosylalanine in R2Sn(Tyr-Ala) acts as dianionic tridentate ligand coordinating through carboxylate oxygen [–C(O)O−], amino (–NH2), and (CO)Npeptide- nitrogen, while in the case of R3Sn(HTyr-Ala), the ligand acts as monoanionic bidentate coordinating through –C(O)O− and –NH2, and the polyhedron around tin in R2Sn(Tyr-Ala) and R3Sn(HTyr-Ala) is a distorted trigonal-bipyramidal. Equilibrium (pH-metric) studies of the interaction of Me2Sn(IV)2+ and Me3Sn(IV)+ with dipeptides namely, tyrosylalanine (H2Tyr-Ala), glycyltyrosine (H2Gly-Tyr), and glycylisoleucine (H2Gly-Ile), in aqueous solution (I = 0.1 M KNO3, 298 K) have also been carried out. The concentration distribution of the various complex species in solution has been evaluated as a function of pH. It has been found that in these dipeptides, [–C(O)O−, N−, NH2] coordinated complexes are dominant in the neutral pH range with a trigonal-bipyramidal structure. The complex species formed are water soluble in the pH range 2.7–10.5. In all of the studied systems, no polymeric species have been detected in the experimental pH range. Beyond pH 8.0, significant amounts of hydroxo species, namely. Me3Sn(OH) and Me2Sn(OH)2, are formed.

scholarly journals Modern Methods for the Sustainable Synthesis of Metalloporphyrins

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6652
Author(s):  
Carla Gomes ◽  
Mariana Peixoto ◽  
Marta Pineiro
Keyword(s):  
Metal Salt ◽  
Reaction Times ◽  
Good Alternative ◽  
Mechanical Action ◽  
Palladium Complexes ◽  
Water Soluble ◽  
Efficient Manner ◽  
Rational Development ◽  
High Yields ◽  
Adequate Method

Metalloporphyrins are involved in many and diverse applications that require the preparation of these compounds in an efficient manner, which nowadays, also involves taking into consideration sustainability issues. In this context, we use ball milling mechanochemistry and sonochemistry for the rational development of synthetic strategies for the sustainable preparation of metalloporphyrins. Zinc, copper, cobalt and palladium complexes of hydrophobic porphyrins were obtained in high yields and under mechanical action with a moderate excess of the metal salt, without any solvent or additive. Sonochemistry prove to be a good alternative for the preparation of metal complexes of water-soluble porphyrins in good yields and short reaction times. Both strategies have good sustainability scores, close to the ideal values, which is useful in comparing and helping to choose the more adequate method.

Phosphine-Free, Efficient Double Carbonylation of Aryl Iodides with Amines Catalyzed by Water-Insoluble and Water-Soluble N-Heterocyclic Carbene-Amine Palladium Complexes

2014 ◽  
Vol 356 (11-12) ◽  
pp. 2539-2546 ◽  
Author(s):  
Yan Wang ◽  
Xiaolong Yang ◽  
Chunyan Zhang ◽  
Jianqiang Yu ◽  
Jianhua Liu ◽  
...  
Keyword(s):  
Palladium Complexes ◽  
Water Soluble ◽  
Aryl Iodides

Nickel(0) and Palladium(0) Complexes with 1,3,5-Triaza-7-phosphaadamantane. Catalysis of Buta-1,3-diene Oligomerization or Telomerization in an AqueousBiphasic System

1997 ◽  
Vol 62 (2) ◽  
pp. 355-363 ◽  
Author(s):  
Jan Čermák ◽  
Magdalena Kvíčalová ◽  
Vratislav Blechta
Keyword(s):  
Metal Complexes ◽  
Nmr Spectra ◽  
High Selectivity ◽  
Palladium Complexes ◽  
Water Soluble ◽  
Biphasic System ◽  
Product Phase ◽  
Aqueous Biphasic System ◽  
Soluble Ligand ◽  
Aqueous Biphasic

New homoleptic nickel(0) and palladium(0) complexes with a water-soluble ligand, 1,3,5-triaza-7-phosphaadamantane, were prepared and characterized by 1H, 13C, and 31P NMR spectra. The complexes, together with the known analogous Ni(0) and Pd(0) complexes with tris(hydroxymethyl)phosphine, were found to be catalysts for buta-1,3-diene oligomerization or telomerization with water in an aqueous biphasic system without a cosolvent or a modifier. Tetrakis[tris(hydroxymethyl)phosphine]nickel (7) preferentially catalyzes oligomerization (both linear and cyclic) in the first example of a nickel-catalyzed buta-1,3-diene oligomerization in an aqueous biphasic system. Palladium complexes give telomers or linear oligomers in quantitative yields. In the case of the triazaphosphaadamantane complex 4, high selectivity to octadienyl ethers (87%) was observed. High values of metal leaching into the product phase in these reactions suggest an easy extraction of starting or intermediate metal complexes caused by the fact that both monomer and products are good ligands for the metal complexes in this particular case.

Sign in / Sign up

Export Citation Format

Share Document