Evaluation of Anticancer Activity of Water-Soluble Curcumin through the Induction of Apoptosis by p53 and p21 Modulation

2018 ◽  
Vol 3 (11) ◽  
pp. 2976-2981 ◽  
Author(s):  
Govindharasu Banuppriya ◽  
Ganeshan Shakambari ◽  
Rajendran Sribalan ◽  
Perumal Varalakshmi ◽  
Vediappen Padmini
Keyword(s):  
Anticancer Activity ◽  
Water Soluble ◽  
Induction Of Apoptosis

scholarly journals Photoactivated in Vitro Anticancer Activity of Rhenium(I) Tricarbonyl Complexes Bearing Water-Soluble Phosphines

2018 ◽  
Vol 57 (3) ◽  
pp. 1311-1331 ◽  
Author(s):  
Sierra C. Marker ◽  
Samantha N. MacMillan ◽  
Warren R. Zipfel ◽  
Zhi Li ◽  
Peter C. Ford ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Water Soluble ◽  
Water Soluble Phosphines

scholarly journals Synthesis, Structure, and Anticancerous Properties of Silver Complexes

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Shraddha Shukla ◽  
A. P. Mishra
Keyword(s):  
Anticancer Activity ◽  
Tumor Cells ◽  
Cancer Cell ◽  
Cell Biology ◽  
Sequence Data ◽  
Analysis Data ◽  
Mixed Ligand ◽  
Water Soluble ◽  
Mixed Ligand Complexes ◽  
Elemental Analysis Data

Although the “war on cancer” is now in its fourth decade and much progress has been made in categorizing the environmental causes and cellular and molecular biological basis for this dreaded disease, we still do not have a precise understanding of the differences between a cancer cell and its normal counterpart. The completion of the human genome sequence and its subsequent improvements in the sequence data are important steps to fully comprehend cancer cell biology. Ag(I) is being used as an anticancer agent in several human cancers. The anticancer activity of these complexes againstEhrlich’s ascitestumor cells (EACs) has been reported. The aim of the present study is to synthesize some new water soluble Ag(I) mixed ligand complexes containing nitrogen and sulfur base and to evaluate their biomedicinal properties. Mixed ligand complexes of Ag(I) metal derived from L-lysine and thiouracil with 2,2′-bipyridyl; 2-aminopyridine with thiouracil have been synthesized. The composition of the prepared complexes was discussed on the basis of microanalysis, FAB-mass, and FT-ir, measurements. Molecular weight was confirmed by FAB-mass spectra. The elemental analysis data suggest the stoichiometry to be M : L : L′ (1 : 1 : 1) ratio. These Ag(I) mixed ligand complexes showed excellent anticancer activity againstEhrlich’s ascitestumor cells (EACs).

Magnetic nanoparticles: mechanistic studies on the cancer cell interaction

2016 ◽  
Vol 5 (5) ◽  
Author(s):  
Joe Antony Jacob ◽  
Jumah Masoud Mohammad Salmani ◽  
Baoan Chen
Keyword(s):  
Cell Death ◽  
Magnetic Nanoparticles ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Cell Interaction ◽  
Mechanistic Studies ◽  
Normal Cells ◽  
Different Types ◽  
Induction Of Apoptosis ◽  
Plausible Reason

AbstractMagnetic nanoparticles are renowned for their anticancer activity. Recent studies have elucidated that magnetic nanoparticles induce cytotoxicity by induction of apoptosis in cancer cells. The magnetic nanoparticles can also be biosynthesized, and this presents an added advantage along with the concept of limited toxicity to normal cells. This review focuses on the mechanistic studies performed on the anticancer activity of different types of magnetic nanoparticles. Apoptosis was shown to be the most plausible reason behind the cell death mediated by various types of magnetic nanoparticles.

scholarly journals Chitosan exerts anticancer activity through induction of apoptosis and cell cycle arrest in oral cancer cells

2014 ◽  
Vol 56 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Yuniardini S. Wimardhani ◽  
Dewi F. Suniarti ◽  
Hans J. Freisleben ◽  
Septelia I. Wanandi ◽  
Nurjati C. Siregar ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Oral Cancer ◽  
Anticancer Activity ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Cycle Arrest ◽  
Induction Of Apoptosis ◽  
Oral Cancer Cells
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