A framework for considering the risk‐benefit trade‐off in designing noninferiority trials using composite outcome approaches

Grace Montepiedra; Ritesh Ramchandani; Sachiko Miyahara; Soyeon Kim

doi:10.1002/sim.8777

A framework for considering the risk‐benefit trade‐off in designing noninferiority trials using composite outcome approaches

Statistics in Medicine ◽

10.1002/sim.8777 ◽

2020 ◽

Vol 40 (2) ◽

pp. 327-348

Author(s):

Grace Montepiedra ◽

Ritesh Ramchandani ◽

Sachiko Miyahara ◽

Soyeon Kim

Keyword(s):

Composite Outcome ◽

Trade Off ◽

Noninferiority Trials

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A Flow-Preserving Algorithm for the Time-Cost Trade-Off Problem

IIE Transactions ◽

10.1080/05695558208974589 ◽

1982 ◽

Vol 14 (2) ◽

pp. 109-113 ◽

Cited By ~ 4

Author(s):

Suleyman Tufekci

Keyword(s):

Time Cost ◽

Trade Off

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Dual Goals for Speed and Accuracy on the Same Performance Task

Journal of Personnel Psychology ◽

10.1027/1866-5888/a000063 ◽

2012 ◽

Vol 11 (3) ◽

pp. 118-126 ◽

Cited By ~ 3

Author(s):

Olive Emil Wetter ◽

Jürgen Wegge ◽

Klaus Jonas ◽

Klaus-Helmut Schmidt

Keyword(s):

Memory Scanning ◽

Performance Task ◽

Performance Tasks ◽

Trade Off ◽

Test Experiment ◽

Trade Offs ◽

New Finding ◽

Sternberg Paradigm ◽

Speed Accuracy ◽

Speed And Accuracy

In most work contexts, several performance goals coexist, and conflicts between them and trade-offs can occur. Our paper is the first to contrast a dual goal for speed and accuracy with a single goal for speed on the same task. The Sternberg paradigm (Experiment 1, n = 57) and the d2 test (Experiment 2, n = 19) were used as performance tasks. Speed measures and errors revealed in both experiments that dual as well as single goals increase performance by enhancing memory scanning. However, the single speed goal triggered a speed-accuracy trade-off, favoring speed over accuracy, whereas this was not the case with the dual goal. In difficult trials, dual goals slowed down scanning processes again so that errors could be prevented. This new finding is particularly relevant for security domains, where both aspects have to be managed simultaneously.

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