Gene selection for microarray data analysis using principal component analysis

2005 ◽  
Vol 24 (13) ◽  
pp. 2069-2087 ◽  
Author(s):  
Antai Wang ◽  
Edmund A. Gehan
Keyword(s):  
Principal Component Analysis ◽  
Data Analysis ◽  
Microarray Data ◽  
Gene Selection ◽  
Principal Component ◽  
Component Analysis ◽  
Microarray Data Analysis ◽  
Selection For

A composite gene selection for DNA microarray data analysis

2013 ◽  
Vol 74 (20) ◽  
pp. 9031-9041 ◽  
Author(s):  
Dong Kyun Park ◽  
Eun-Young Jung ◽  
Sang-Hong Lee ◽  
Joon S. Lim
Keyword(s):  
Data Analysis ◽  
Dna Microarray ◽  
Microarray Data ◽  
Gene Selection ◽  
Microarray Data Analysis ◽  
Dna Microarray Data ◽  
Selection For

Reaction Monitoring in Explorative Organic Synthesis Using Fiber-Optical NIR Spectroscopy and Principal Component Analysis

1996 ◽  
Vol 50 (12) ◽  
pp. 1541-1544 ◽  
Author(s):  
Hans-René Bjørsvik
Keyword(s):  
Principal Component Analysis ◽  
Data Analysis ◽  
Latent Variables ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Principal Component ◽  
Component Analysis ◽  
Quantitative Information ◽  
Chemistry Laboratory ◽  
Reaction Profile

A method of combining spectroscopy and multivariate data analysis for obtaining quantitative information on how a reaction proceeds is presented. The method is an approach for the explorative synthetic organic laboratory rather than the analytical chemistry laboratory. The method implements near-infrared spectroscopy with an optical fiber transreflectance probe as instrumentation. The data analysis consists of decomposition of the spectral data, which are recorded during the course of a reaction by using principal component analysis to obtain latent variables, scores, and loading. From the scores and the corresponding reaction time, it is possible to obtain a reaction profile. This reaction profile can easily be recalculated to obtain the concentration profile over time. This calculation is based on only two quantitative measurements, which can be (1) measurement from the work-up of the reaction or (2) chromatographic analysis from two withdrawn samples during the reaction. The method is applied to the synthesis of 3-amino-propan-1,2-diol.

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