scholarly journals Expanded Access Protocol of Umbilical Cord Blood Infusion for Children with Neurological Conditions

2019 ◽  
Vol 8 (S1) ◽  
Author(s):  
Colleen A. McLaughlin ◽  
Tara West ◽  
Rachel Hollowell ◽  
Natalie N. Skergan ◽  
Jennifer Baker ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Access Protocol ◽  
Expanded Access ◽  
Neurological Conditions

scholarly journals Expanded Access Protocol of Umbilical Cord Blood Infusion for Children with Neurological Conditions: An Update

2021 ◽  
Vol 10 (S1) ◽  
Author(s):  
Colleen McLaughlin ◽  
Tara West ◽  
Rachel Hollowell ◽  
Natalie Skergan ◽  
Paige Giguere ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Access Protocol ◽  
Expanded Access ◽  
Neurological Conditions

Oxygen Consumption in Platelets of Newborn Infants before and after Stimulation by Thrombin.

1976 ◽  
Vol 35 (03) ◽  
pp. 712-716 ◽  
Author(s):  
D. Del Principe ◽  
G Mancuso ◽  
A Menichelli ◽  
G Maretto ◽  
G Sabetta
Keyword(s):  
Oxygen Consumption ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Newborn Infant ◽  
Umbilical Cord Blood ◽  
Newborn Infants ◽  
O2 Consumption ◽  
Adult Control ◽  
Healthy Newborn ◽  
Before And After

SummaryThe authors compared the oxygen consumption in platelets from the umbilical cord blood of 36 healthy newborn infants with that of 27 adult subjects, before and after thrombin addition (1.67 U/ml). Oxygen consumption at rest was 6 mμmol/109/min in adult control platelets and 5.26 in newborn infants. The burst in oxygen consumption after thrombin addition was 26.30 mμmol/109/min in adults and 24.90 in infants. Dinitrophenol did not inhibit the burst of O2 consumption in platelets in 8 out of 10 newborn infants, while the same concentration caused a decrease in 9 out of 10 adult subjects. Deoxyglucose inhibited the burst in O2 consumption in newborn infant and adult platelets by about 50%. KCN at the concentration of 10−4 M completely inhibited basal oxygen consumption but did not completely inhibit the burst after thrombin. At the concentration of 10−3 M, it inhibited both basal O2 consumption and the burst in infants and adult subjects.

Feasibility of umbilical cord blood (UCB) collection in neonates at high risk of brain damage

2018 ◽  
Author(s):  
A Segler ◽  
A Schwickert ◽  
CR Weiß ◽  
C Bührer ◽  
T Braun ◽  
...  
Keyword(s):  
High Risk ◽  
Cord Blood ◽  
Brain Damage ◽  
Umbilical Cord ◽  
Umbilical Cord Blood
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