Classification of nerve action potentials for estimation of sensory unit activity

2002 ◽  
Vol 33 (6) ◽  
pp. 44-52
Author(s):  
Hironori Nakatani ◽  
Takashi Watanabe ◽  
Shigeo Ohba ◽  
Nozomu Hoshimiya
1968 ◽  
Vol 6 (2) ◽  
pp. 209-212 ◽  
Author(s):  
Hampton W. Shirer ◽  
Nancy Ann Dahl

2000 ◽  
Vol 88 (4) ◽  
pp. 1489-1495 ◽  
Author(s):  
David F. Donnelly ◽  
Ricardo Rigual

A preparation was developed that allows for the recording of single-unit chemoreceptor activity from mouse carotid body in vitro. An anesthetized mouse was decapitated, and each carotid body was harvested, along with the sinus nerve, glossopharyngeal nerve, and petrosal ganglia. After exposure to collagenase/trypsin, the cleaned complex was transferred to a recording chamber where it was superfused with oxygenated saline. The ganglia was searched for evoked or spontaneous unit activity by using a glass suction electrode. Single-unit action potentials were 57 ± 10 (SE) ( n = 16) standard deviations above the recording noise, and spontaneous spikes were generated as a random process. Decreasing superfusate[Formula: see text] to near 20 Torr caused an increase in spiking activity from 1.3 ± 0.4 to 14.1 ± 1.9 Hz ( n = 16). The use of mice for chemoreceptor studies may be advantageous because targeted gene deletions are well developed in the mouse model and may be useful in addressing unresolved questions regarding the mechanism of chemotransduction.


1967 ◽  
Vol 70 (5) ◽  
pp. 920-931
Author(s):  
NOBUO YOSHIE ◽  
TORU OHASHI

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