scholarly journals Use of GMI‐1271, an E‐selectin antagonist, in healthy subjects and in 2 patients with calf vein thrombosis

2020 ◽  
Vol 4 (2) ◽  
pp. 193-204
Author(s):  
Sumana Devata ◽  
Dana E. Angelini ◽  
Susan Blackburn ◽  
Angela Hawley ◽  
Daniel D. Myers ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Vein Thrombosis ◽  
Calf Vein

Trial of Aspirin and RA 233 in Prevention of Post-operative Deep Vein Thrombosis

1973 ◽  
Vol 30 (01) ◽  
pp. 018-024 ◽  
Author(s):  
Edward H. Wood ◽  
Colin R.M. Prentice ◽  
D. Angus McGrouther ◽  
John Sinclair ◽  
George P. McNicol
Keyword(s):  
Deep Vein Thrombosis ◽  
Controlled Trial ◽  
Oral Anticoagulants ◽  
Antithrombotic Agent ◽  
Fractured Neck Of Femur ◽  
Neck Of Femur ◽  
Vein Thrombosis ◽  
Effective Prophylaxis ◽  
Deep Vein ◽  
Calf Vein

SummaryAlthough the oral anticoagulants provide effective prophylaxis against postoperative deep vein thrombosis following fracture of neck of femur there is a need for an antithrombotic agent which needs less laboratory control and does not cause haemorrhagic complications. It has been suggested that drugs causing inhibition of platelet function may fulfil these requirements. A controlled trial was carried out in which aspirin, RA 233, or a combination of these drugs was compared with a placebo in the prevention of post-operative deep vein thrombosis. In thirty patients undergoing surgery for fractured neck of femur the incidence of post-operative calf vein thrombosis, as detected by 125I-fibrinogen scanning, was not significantly different between the untreated and treated groups.

Case #2: Calf Vein Thrombosis

1997 ◽  
Vol 31 (3) ◽  
pp. 332-337
Author(s):  
Russell D. Hull ◽  
Elna M. Masuda ◽  
Andrew N. Nicolaides ◽  
Hugo Partsch ◽  
D. Eugene Strandness ◽  
...  
Keyword(s):  
Vein Thrombosis ◽  
Calf Vein

scholarly journals Pulsatility Index of Popliteal Artery in Patients with Isolated Calf Vein Thrombosis: A Novel Technique for Detecting Thrombosis

2017 ◽  
Vol 82 ◽  
pp. 161-164
Author(s):  
Abdussamet Batur ◽  
Vural Polat ◽  
Mesut Ozgokce ◽  
Muhammed Alpaslan ◽  
Alpaslan Yavuz ◽  
...  
Keyword(s):  
Popliteal Artery ◽  
Pulsatility Index ◽  
Vein Thrombosis ◽  
Novel Technique ◽  
Calf Vein

The calf vein thrombosis

2013 ◽  
Vol 1 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Pier Luigi Antignani ◽  
Leonardo Aluigi
Keyword(s):  
Vein Thrombosis ◽  
Calf Vein

No consensus exists for use of anticoagulation for calf vein thrombosis

Vascular ◽  
2013 ◽  
Vol 22 (2) ◽  
pp. 93-97 ◽  
Author(s):  
Michael J Anstadt ◽  
T Calloway Robertson ◽  
Ross Milner
Keyword(s):  
Online Survey ◽  
Practice Patterns ◽  
Low Molecular Weight ◽  
Multiple Choice Questions ◽  
Single Institution ◽  
Vein Thrombosis ◽  
Ivc Filters ◽  
Calf Vein ◽  
The Ideal

The ideal treatment of calf vein thrombosis (CVT) remains undefined. We assessed practice patterns at a single institution for CVT. Physicians were sent an online survey with 8 multiple choice questions about management of CVT. A total of 99 physicians of varying specialties participated in the survey. A total of 48.5% anticoagulate patients with CVT and 51.5% do not. Of those who anticoagulate, 62.3% use low molecular weight heparin and 11% use IV heparin. Treatment duration is 3 months for 58% and 6 months for 30% of responders. Of those who do not anticoagulate, 71.2% reassess for clot propagation or resolution with a duplex exam. IVC filters are used by 46% when there is a contraindication to anticoagulation and 13.7% when clot propagation is noted on follow-up scan. These results suggest that there is no consensus treatment of CVT. There is a higher than expected rate of IVC filters placed for CVT.

Characterization of intramuscular calf vein thrombosis on routine knee MRI

2019 ◽  
Vol 48 (10) ◽  
pp. 1573-1580
Author(s):  
David P. Duncan ◽  
Michael Taddonio ◽  
Eric Y. Chang ◽  
Brady K. Huang
Keyword(s):  
Vein Thrombosis ◽  
Knee Mri ◽  
Calf Vein

Thrombophilic Genotypes in Subjects with Idiopathic Antiphospholipid Antibodies – Prevalence and Significance

1998 ◽  
Vol 79 (01) ◽  
pp. 46-49 ◽  
Author(s):  
Catello Tommasino ◽  
Giovanna D’Andrea ◽  
Luigi Iannaccone ◽  
Vincenzo Brancaccio ◽  
Maurizio Margaglione ◽  
...  
Keyword(s):  
Antiphospholipid Antibodies ◽  
Healthy Subjects ◽  
Methylenetetrahydrofolate Reductase ◽  
Thrombotic Event ◽  
Significant Proportion ◽  
Factor V ◽  
Vein Thrombosis ◽  
History Of ◽  
Fv Leiden

SummaryTo evaluate the significance of common thrombophilic genotypes in subjects with idiopathic antiphospholipid antibodies (aPL) we determined the methylenetetrahydrofolate reductase C677→ (MTHFR) and factor V A506→ G (FV Leiden) polymorphisms in 49 subjects with idiopathic aPL (57% of whom suffered spontaneous vein thrombosis), in 70 subjects with a history of spontaneous vein thrombosis and in 193 healthy subjects. The prevalence of MTHFR C677→+/+ (homozygotes) was 25%, 18% and 17% respectively amongst aPL thrombotics, non aPL thrombotics and controls and that of MTHFR C677→+/– (heterozygotes) was 53%, 59% and 53% respectively in the same groups. The prevalence of FV Leiden was higher in aPL thrombotics (14%) and in non aPL thrombotics (18%) than in controls (4%) (p ≤ = 0.05). APL thrombotics with MTHFR C677→+/+ had a lower mean age at first thrombotic event (22 ± 6 years) than aPL thrombotics with MTHFR C677→+/– and non mutated considered together (38 ± 14 years, p = 0.0004) and than non aPL thrombotics with MTHFR C677→+/+ (38 ± 14 years, p = 0.003). FV Leiden may con tribute to the hypercoagulability of a small, albeit significant proportion of thrombotic aPL subjects, whereas the association between MTHFR C677→+/+ and aPL may have an impact on age at first occlusive event and suggests a possible pathogenetic interaction.

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