Evidence and controversies on the role of XMRV in prostate cancer and chronic fatigue syndrome

2010 ◽  
Vol 21 (1) ◽  
pp. 3-17 ◽  
Author(s):  
Luis Menéndez-Arias
Keyword(s):  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

scholarly journals Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Human Herpesviruses Are Back!

Biomolecules ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 185
Author(s):  
Maria Eugenia Ariza
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Disease Process ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
Barr Virus ◽  
Fatigue Syndrome ◽  
Specific Proteins ◽  
Epstein Barr ◽  
Human Herpesviruses

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) or Systemic Exertion Intolerance Disease (SEID) is a chronic multisystem illness of unconfirmed etiology. There are currently no biomarkers and/or signatures available to assist in the diagnosis of the syndrome and while numerous mechanisms have been hypothesized to explain the pathology of ME/CFS, the triggers and/or drivers remain unknown. Initial studies suggested a potential role of the human herpesviruses especially Epstein-Barr virus (EBV) in the disease process but inconsistent and conflicting data led to the erroneous suggestion that these viruses had no role in the syndrome. New studies using more advanced approaches have now demonstrated that specific proteins encoded by EBV could contribute to the immune and neurological abnormalities exhibited by a subgroup of patients with ME/CFS. Elucidating the role of these herpesvirus proteins in ME/CFS may lead to the identification of specific biomarkers and the development of novel therapeutics.

The Role of Perfectionism in Chronic Fatigue Syndrome

2015 ◽  
pp. 101-118 ◽  
Author(s):  
Stefan Kempke ◽  
Boudewijn Van Houdenhove ◽  
Stephan Claes ◽  
Patrick Luyten
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

scholarly journals The role of herpesviruses 6 and 7 in the development of chronic fatigue syndrome: a review of literature and description of clinical cases

2018 ◽  
pp. 24-31
Author(s):  
V. V. Tsaryk ◽  
A. K. Novoskoltsev
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Drug Treatment ◽  
Fibromyalgia Syndrome ◽  
Immune Dysfunction ◽  
Chronic Fatigue ◽  
Point Of View ◽  
Review Of Literature ◽  
Herpesvirus Infection ◽  
Fatigue Syndrome

At the issue represented the etiopathogenesis of the chronic fatigue syndrome of (CFS) with immune dysfunction. Many doctors consider this problem only from the point of view of non-psychological disorders requiring only psycho-correction and non-drug treatment. However, syndromocomplex of CFS includes not only neuropsychiatric disorders, but also fibromyalgia syndrome, unexplained genesis, lymphadenopathy, non-specific polyarthralgias. It is also controversial about the feasibility of treating type 6 herpesviruses and type 7 viruses. Some authors consider the need for antiviral therapy only when reactivating the herpesvirus infection, in the transplantation of organs and tissues. However, for frequent HHV-7 and HHV-6 viremia remains resistant to ganciclovir, unlike CMV and EBV, which is successfully controlled by viremia.

scholarly journals Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): An Overview

2021 ◽  
Vol 10 (20) ◽  
pp. 4786
Author(s):  
Undine-Sophie Deumer ◽  
Angelica Varesi ◽  
Valentina Floris ◽  
Gabriele Savioli ◽  
Elisa Mantovani ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Chronic Fatigue Syndrome ◽  
Systemic Disease ◽  
Disease Onset ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
Diagnostic Tools ◽  
Fatigue Syndrome ◽  
Non Coding Rna

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic systemic disease that manifests via various symptoms such as chronic fatigue, post-exertional malaise, and cognitive impairment described as “brain fog”. These symptoms often prevent patients from keeping up their pre-disease onset lifestyle, as extended periods of physical or mental activity become almost impossible. However, the disease presents heterogeneously with varying severity across patients. Therefore, consensus criteria have been designed to provide a diagnosis based on symptoms. To date, no biomarker-based tests or diagnoses are available, since the molecular changes observed also largely differ from patient to patient. In this review, we discuss the infectious, genetic, and hormonal components that may be involved in CFS pathogenesis, we scrutinize the role of gut microbiota in disease progression, we highlight the potential of non-coding RNA (ncRNA) for the development of diagnostic tools and briefly mention the possibility of SARS-CoV-2 infection causing CFS.

scholarly journals Chronic fatigue syndrome Role of psychological factors overemphasised

BMJ ◽  
1994 ◽  
Vol 308 (6939) ◽  
pp. 1297-1301 ◽  
Author(s):  
C Blatch ◽  
T Blatt ◽  
A Wilson ◽  
I Hickie ◽  
A Lloyd ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Psychological Factors ◽  
Chronic Fatigue ◽  
Fatigue Syndrome
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