scholarly journals Novel approaches to the management of recurrent pregnancy loss: The OPTIMUM (OPtimization of Thyroid function, Thrombophilia, Immunity, and Uterine Milieu) treatment strategy

2021 ◽  
Vol 20 (4) ◽  
pp. 524-536
Author(s):  
Keiji Kuroda ◽  
Yuko Ikemoto ◽  
Takashi Horikawa ◽  
Azusa Moriyama ◽  
Yuko Ojiro ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Treatment Strategy ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Novel Approaches ◽  
Milieu Treatment

scholarly journals Abnormal Thyroid Function and Recurrent Pregnancy Loss

2014 ◽  
Vol 9 (1) ◽  
pp. 29-32
Author(s):  
A Shrestha ◽  
CD Chawla
Keyword(s):  
Longitudinal Study ◽  
Thyroid Function ◽  
Autoimmune Thyroiditis ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Disorder ◽  
Positive Message ◽  
Effect Of Treatment ◽  
Tsh Levels

Aims: The aim of our study was to observe the benefit of screening for thyroid function amongst women with recurrent pregnancy loss and effect of treatment for thyroid disorder on pregnancy outcome. Methods: This was a longitudinal study conducted from June 2012 to December 2013. One hundred and three patients with recurrent pregnancy loss without features of thyroid disorder were included. They were investigated for thyroid stimulating hormone (TSH), free tri iodothyronin (FT3), free thyroxine (FT4) levels and for auto-antibodies against thyroperoxidase (anti TPO). The patients with abnormal TSH levels were treated with thyroxine depending on the level of TSH. Results: TSH, FT3, FT4 and anti TPO levels were measured. Amongst 103 ladies, thirty-eight (36.89%) had high levels of TSH. Thirty-five (33.98%) of them underwent test for anti TPO, of which two (5.71%) had autoimmune thyroiditis. Nine (8.73%) out of 103 had high FT4 levels. Ladies with diagnosis of hypothyroidism underwent treatment and 17 (44.73%) out of 38 had conceived. Conclusions: Of 103 women with recurrent pregnancy loss, abnormal thyroid function was detected in 47. Seventeen (44.73%) of them with increased TSH level conceived after treatment with thyroxine, which gives a positive message that hypothyroidism is a treatable cause for recurrent pregnancy loss. DOI: http://dx.doi.org/10.3126/njog.v9i1.11184 NJOG 2014 Jan-Jun; 2(1):29-32

Thyroid peroxidase antibodies do not predict outcome in 900 women with recurrent pregnancy loss

2017 ◽  
Author(s):  
Sofie Bliddal ◽  
Nielsen Henriette Svarre ◽  
Aase Krogh-Rasmussen ◽  
Kolte Astrid Marie ◽  
Christiansen Ole Bjarne ◽  
...  
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Thyroid Peroxidase ◽  
Thyroid Peroxidase Antibodies

Prophylactic Measures in Early Recurrent Pregnancy Loss in Women with Polycystic Ovary Syndrome and Hyperhomocysteinemia

2019 ◽  
Vol 87 (March) ◽  
pp. 195-199
Author(s):  
MAHMOUD F. MAHDIA, M.Sc. TAREK M. EL-HAWARY, M.D. ◽  
SHAHENAZ H. EL-SHORBAGY, M.D. NAREMAAN M. EL-HAMAMY, M.D.
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Prophylactic Measures

Differentially expressed circulating microRNAs associated with idiopathic recurrent pregnancy loss

Gene ◽  
2021 ◽  
Vol 768 ◽  
pp. 145334
Author(s):  
Deeba S. Jairajpuri ◽  
Zainab H. Malalla ◽  
Naeema Mahmood ◽  
Farah Khan ◽  
Wassim Y. Almawi
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Differentially Expressed ◽  
Circulating Micrornas
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