scholarly journals Haemorrhagic bronchial casts causing complete ventilatory failure in a COVID ‐19 patient on ECMO

2020 ◽  
Vol 8 (7) ◽  
Author(s):  
Samantha Herath ◽  
Natalie Kruit ◽  
Adam Eslick ◽  
Nicole Giroy
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Badrul Islam ◽  
Mohiuddin Ahmed ◽  
Zhahirul Islam ◽  
S. M. Begum

Abstract Background SARS-CoV2 virus could be potentially myopathic. Serum creatinine phosphokinase (CPK) is frequently found elevated in severe SARS-CoV2 infection, which indicates skeletal muscle damage precipitating limb weakness or even ventilatory failure. Case presentation We addressed such a patient in his forties presented with features of severe SARS-CoV2 pneumonia and high serum CPK. He developed severe sepsis and acute respiratory distress syndrome (ARDS) and received intravenous high dose corticosteroid and tocilizumab to counter SARS-CoV2 associated cytokine surge. After 10 days of mechanical ventilation (MV), weaning was unsuccessful albeit apparently clear lung fields, having additionally severe and symmetric limb muscle weakness. Ancillary investigations in addition with serum CPK, including electromyogram, muscle biopsy, and muscle magnetic resonance imaging (MRI) suggested acute myopathy possibly due to skeletal myositis. Conclusion We wish to stress that myopathogenic medication in SARS-CoV2 pneumonia should be used with caution. Additionally, serum CPK could be a potential marker to predict respiratory failure in SARS-CoV2 pneumonia as skeletal myopathy affecting chest muscles may contribute ventilatory failure on top of oxygenation failure due to SARS-CoV2 pneumonia.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Sheila A. Habib ◽  
Robert C. Vasko ◽  
Jack Badawy ◽  
Gregory M. Anstead

Plastic bronchitis is the expectoration of bronchial casts in the mold of the tracheobronchial tree. It is a rare occurrence of unknown etiology that has been primarily described in children with congenital heart disease. In this case report, we present the first reported case of plastic bronchitis in a patient with pulmonary Kaposi sarcoma and underlying HIV infection.


CHEST Journal ◽  
1991 ◽  
Vol 99 (2) ◽  
pp. 444-451 ◽  
Author(s):  
Cecil O. Borel ◽  
Charles Tilford ◽  
David G. Nichols ◽  
Daniel F. Hardey ◽  
Richard J. Traystman

1990 ◽  
Vol 37 (5) ◽  
pp. 587-588 ◽  
Author(s):  
Gordon Wood ◽  
Brian Milne ◽  
Victor Spjeda ◽  
Jlee Lewis

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