The effects of rutin and troxerutin on stabilizing SOD1 and inhibiting protein aggregation

2020 ◽  
Vol 34 (6) ◽  
Author(s):  
Xiaoyu Zhuang ◽  
Bing Zhao ◽  
Zhiqiang Liu ◽  
Fengrui Song ◽  
Jianzhong Lu
Keyword(s):  
Protein Aggregation ◽  
Inhibiting Protein

scholarly journals Impact of porous nanomaterials on inhibiting protein aggregation behaviour

RSC Advances ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 3354-3362
Author(s):  
Munmun Bardhan ◽  
Sandip Dolui ◽  
Siddhi Chaudhuri ◽  
Uttam Paul ◽  
Gaurav Bhattacharjee ◽  
...  
Keyword(s):  
Protein Aggregation ◽  
Physiological Conditions ◽  
Intrinsically Disordered ◽  
Aggregation Behaviour ◽  
Inhibiting Protein ◽  
Porous Nanomaterials

Aggregation of intrinsically disordered as well as the ordered proteins under certain premises or physiological conditions leads to pathological disorder.

Small-Molecule-Functionalized Hyperbranched Polyglycerol Dendrimers for Inhibiting Protein Aggregation

2020 ◽  
Vol 21 (8) ◽  
pp. 3270-3278
Author(s):  
Suman Mandal ◽  
Prasanta Panja ◽  
Koushik Debnath ◽  
Nihar R. Jana ◽  
Nikhil R. Jana
Keyword(s):  
Protein Aggregation ◽  
Small Molecule ◽  
Hyperbranched Polyglycerol ◽  
Inhibiting Protein ◽  
Polyglycerol Dendrimers

An Ultra-Structural Study of Human Melanoma in Vivo and Vitro

1976 ◽  
Vol 34 ◽  
pp. 258-259
Author(s):  
James R. Gaylor ◽  
Fredda Schafer ◽  
Robert E. Nordquist
Keyword(s):  
Endoplasmic Reticulum ◽  
Golgi Apparatus ◽  
Protein Aggregation ◽  
Structural Study ◽  
Human Melanoma ◽  
Protein Matrix ◽  
Early Form ◽  
Endoplasmic Reticulum Protein ◽  
Mitochondrial Origin

Several theories on the origin of the melanosome exist. These include the Golgi origin theory, in which a tyrosinase-rich protein is "packaged" by the Golgi apparatus, thus forming the early form of the melanosome. A second theory postulates a mitochondrial origin of melanosomes. Its author contends that the melanosome is a modified mitochondria which acquires melanin during its development. A third theory states that a pre-melanosome is formed in the smooth or rough endoplasmic reticulum. Protein aggregation is suggested by one author as a possible source of the melanosome. This fourth theory postulates that the melanosome originates when the protein products of several genetic loci aggregate in the cytoplasm of the melanocyte. It is this protein matrix on which the melanin is deposited. It was with these theories in mind that this project was undertaken.

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