High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening

2012 ◽  
Vol 27 (3) ◽  
pp. 401-408 ◽  
Author(s):  
Xiao Ding ◽  
Hesham Ghobarah ◽  
Xiaolin Zhang ◽  
Allan Jaochico ◽  
Xingrong Liu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Small Molecules ◽  
High Throughput ◽  
Drug Screening ◽  
Accurate Mass ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Chromatography Mass Spectrometry

Liquid chromatography-mass spectrometry determination of iloperidone on rat dried blood spots: application to pharmacokinetics

2017 ◽  
Vol 9 (39) ◽  
pp. 5749-5756
Author(s):  
R. Nageswara Rao ◽  
K. Guru Prasad ◽  
Sara Khalid ◽  
K. S. Praneetha ◽  
Dilip Dodda ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Dried Blood Spots ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Blood Spots ◽  
Chromatography Mass Spectrometry ◽  
Highly Sensitive

A simple, rapid and highly sensitive liquid chromatography-mass spectrometry method was developed and validated for analysis of iloperidone on rat dried blood spots.

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