scholarly journals A rapid oxygen exchange on prostaglandins in plasma represents plasma esterase activity that is inhibited by diethylumbelliferyl phosphate with high affinity

2012 ◽  
Vol 26 (20) ◽  
pp. 2472-2476 ◽  
Author(s):  
Stephen A. Brose ◽  
Mikhail Y. Golovko
Keyword(s):  
Esterase Activity ◽  
Oxygen Exchange ◽  
High Affinity ◽  
Plasma Esterase

Plasma esterase activity in patients with aspirin-sensitive asthma or urticaria

1987 ◽  
Vol 33 (4) ◽  
pp. 387-390 ◽  
Author(s):  
F. M. Williams ◽  
S. I. Asad ◽  
M. H. Lessof ◽  
M. D. Rawlins
Keyword(s):  
Esterase Activity ◽  
Plasma Esterase

Etomidate and Plasma Esterase Activity in Man and Experimental Animals

Pharmacology ◽  
1979 ◽  
Vol 18 (6) ◽  
pp. 294-298 ◽  
Author(s):  
R. Calvo ◽  
R. Carlos ◽  
S. Erill
Keyword(s):  
Esterase Activity ◽  
Experimental Animals ◽  
Plasma Esterase

THE SPECTRUM OF PLASMA ESTERASE ACTIVITY IN YOUNG, OLD, AND COLD-ACCLIMATED RATS

1964 ◽  
Vol 42 (12) ◽  
pp. 1711-1715 ◽  
Author(s):  
D. G. Baker ◽  
R. Ghys ◽  
D. Coles ◽  
S. Christie
Keyword(s):  
Esterase Activity ◽  
Accelerated Aging ◽  
Specific Proteins ◽  
Young Old ◽  
Plasma Esterase ◽  
Qualitative Changes

Qualitative changes occurred in the spectrum of plasma esterase activity with increasing age. The trend was toward a decrease in the number of specific proteins having esterase activity. Acclimation to cold did not accelerate the onset of this trend. In the plasma esterase activity during acclimation to cold, there were no changes which would suggest accelerated aging.

Hormonally Sensitive Esterase Activity in the Mouse Uterus Results from Uptake of Plasma Esterase*

Endocrinology ◽  
1984 ◽  
Vol 115 (6) ◽  
pp. 2406-2417 ◽  
Author(s):  
SUSAN S. KADNER ◽  
JOSEPH KATZ ◽  
BRETT A. BERLINER ◽  
MORTIMER LEVITZ ◽  
THOMAS H. FINLAY
Keyword(s):  
Esterase Activity ◽  
Mouse Uterus ◽  
Plasma Esterase

Neuronal and Extraneuronal Uptake of 3H-Norepinephrine in the Heart of the Active Bat: An Electron Microscopic Radioautographic Study

1973 ◽  
Vol 31 ◽  
pp. 522-523
Author(s):  
Martin Hagopian ◽  
Michael D. Gershon ◽  
Eladio A. Nunez
Keyword(s):  
Smooth Muscle ◽  
Monoamine Oxidase ◽  
Vascular Smooth Muscle ◽  
Cardiac Muscle ◽  
Maximum Rate ◽  
External Medium ◽  
Extraneuronal Uptake ◽  
Electron Microscopic ◽  
Cardiac Tissues ◽  
High Affinity

The ability of cardiac tissues to take up norepinephrine from an external medium is well known. Two mechanisms, called Uptake and Uptake respectively by Iversen have been differentiated. Uptake is a high affinity system associated with adrenergic neuronal elements. Uptake is a low affinity system, with a higher maximum rate than that of Uptake. Uptake has been associated with extraneuronal tissues such as cardiac muscle, fibroblasts or vascular smooth muscle. At low perfusion concentrations of norepinephrine most of the amine taken up by Uptake is metabolized. In order to study the localization of sites of norepinephrine storage following its uptake in the active bat heart, tritiated norepinephrine (2.5 mCi; 0.064 mg) was given intravenously to 2 bats. Monoamine oxidase had been inhibited with pheniprazine (10 mg/kg) one hour previously to decrease metabolism of norepinephrine.

Clinical Application and Results of the Assessment of Coronary Blood Flow by the Regional Precordial Xenon Residue Detection Technique

1978 ◽  
Vol 17 (04) ◽  
pp. 161-171
Author(s):  
H.-J. Engel ◽  
H. Hundeshagen ◽  
P. R. Lichtlen
Keyword(s):  
Wall Motion ◽  
High Flow ◽  
Detection Technique ◽  
Fatty Tissue ◽  
Technical Aspects ◽  
Residue Detection ◽  
High Affinity ◽  
Artery Disease ◽  
The Right ◽  
Drug Interventions

Methodological and technical aspects as well as application and results of the precordial Xenon-residue-detection technique are critically reviewed. The results concern mainly normal flow in various regions of the heart esp. in the free wall of the right and left ventricle, poststenotic flow in patients with coronary artery disease in relation to the degree of proximal nar-rowings as well as wall motion of the corresponding LV segment, bypassgraft flow and flow after drug interventions esp. nitrates, betablockers, the calcium-antagonist Nifedipine and the coronary dilator Dipyridamole. In spite of its serious limitations (high affinity of Xenon for fatty tissue, geometrical problems in the assessment of flow and its relation to anatomy, gas exchange in situations of high flow etc.), the technique is found to be a usefull investigatory tool. Due to its technical display and the related high costs routine application is, however, prohibitive.

Binding of 131I-Labeled Tissue-Type Plasminogen Activator on De-Endothelialized Lesions in Rabbits

1987 ◽  
Vol 26 (05) ◽  
pp. 224-228 ◽  
Author(s):  
Y. Isaka ◽  
H. Etani ◽  
K. Kimura ◽  
S. Yoneda ◽  
T. Kamada ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Abdominal Aorta ◽  
Half Life ◽  
Balloon Catheter ◽  
Biochemical Properties ◽  
Tissue Type ◽  
Fibrin Deposition ◽  
Tissue Type Plasminogen Activator ◽  
High Affinity ◽  
Type Plasminogen Activator

Tissue-type plasminogen activator (t-PA) which has a high affinity for fibrin in the clot, was labeled with 131I by the iodogen method, and its binding to de-endothelialized lesions in the rabbit was measured to assess the detectability of thrombi. The de-endothelialized lesion was induced in the abdominal aorta with a Fogarty 4F balloon catheter. Two hours after the de-endothelialization, 131I-labeled t-PA (125 ± 46 μCi) was injected intravenously. The initial half-life of the agent in blood (n = 12) was 2.9 ± 0.4 min. The degree of binding of 131I-labeled t-PA to the de-endothelialized lesion was evaluated at 15 min (n = 6) or at 30 min (n = 6) after injection of the agent. In spite of the retention of the biochemical properties of 131I-labeled t-PA and the presence of fibrin deposition at the de-endothelialized lesion, the binding of t-PA to the lesion was not sufficiently strong. Lesion-to-control ratios (cpm/g/cpm/g) were 1.65 ± 0.40 (at 15 min) and 1.39 ± 1.31 (at 30 min), and lesion-to-blood ratios were 1.39 ± 0.32 (at 15 min) and 1.36 ± 0.23 (at 30 min). These results suggest that radiolabeled t-PA may be inappropriate as a radiopharmaceutical for the scintigraphic detection of a pre-existing thrombotic lesion.

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