Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification

David Q. Liu; Cornelis E.C.A. Hop; Mar�a G. Beconi; Ann Mao; Shuet-Hing Lee Chiu

doi:10.1002/rcm.442

Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.442 ◽

2001 ◽

Vol 15 (19) ◽

pp. 1832-1839 ◽

Cited By ~ 60

Author(s):

David Q. Liu ◽

Cornelis E.C.A. Hop ◽

Mar�a G. Beconi ◽

Ann Mao ◽

Shuet-Hing Lee Chiu

Keyword(s):

Metabolite Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hydrogen Deuterium ◽

On Line

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D. Q. Liu, C. E. C. A. Hop, M. G. Beconi, A. Mao, S.-H. Lee ?Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification?Rapid Communications in Mass Spectrometry, 15(19), 2001, 1832-1839

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.884 ◽

2003 ◽

Vol 17 (3) ◽

pp. 264-264 ◽

Cited By ~ 1

Keyword(s):

Mass Spectrometry ◽

Metabolite Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hydrogen Deuterium ◽

On Line

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A Membrane Cell for On-line Hydrogen/Deuterium Exchange to Study Protein Folding and Protein-Protein Interactions by Mass Spectrometry

Molecular & Cellular Proteomics ◽

10.1074/mcp.m110.006510 ◽

2011 ◽

Vol 10 (9) ◽

pp. M110.006510 ◽

Cited By ~ 8

Author(s):

Juan Astorga-Wells ◽

Michael Landreh ◽

Jan Johansson ◽

Tomas Bergman ◽

Hans Jörnvall

Keyword(s):

Mass Spectrometry ◽

Protein Folding ◽

Protein Interactions ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Protein Protein Interactions ◽

Hydrogen Deuterium ◽

On Line ◽

Membrane Cell

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Online Hydrogen-Deuterium Exchange and a Tandem-Quadrupole Time-of-Flight Mass Spectrometer Coupled with Liquid Chromatography for Metabolite Identification in Drug Metabolism

Journal of Chromatographic Science ◽

10.1093/chromsci/41.8.398 ◽

2003 ◽

Vol 41 (8) ◽

pp. 398-404 ◽

Cited By ~ 32

Author(s):

A.- E. F. Nassar

Keyword(s):

Liquid Chromatography ◽

Drug Metabolism ◽

Mass Spectrometer ◽

Time Of Flight ◽

Metabolite Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Flight Mass Spectrometer ◽

Hydrogen Deuterium ◽

Tandem Quadrupole

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Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2010.03.040 ◽

2010 ◽

Vol 1217 (22) ◽

pp. 3598-3611 ◽

Cited By ~ 6

Author(s):

Min Liu ◽

Mike Ronk ◽

Da Ren ◽

Judy Ostovic ◽

Nina Cauchon ◽

...

Keyword(s):

Mass Spectrometry ◽

Tandem Mass Spectrometry ◽

Structure Elucidation ◽

Deuterium Exchange ◽

Hydrophilic Interaction Chromatography ◽

Tandem Mass ◽

Hydrogen Deuterium Exchange ◽

Hydrophilic Interaction ◽

Hydrogen Deuterium ◽

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Structural identification of trace level enol tautomer impurity by on-line hydrogen/deuterium exchange HR-LC/MS in a LTQ-Orbitrap hybrid mass spectrometer

Journal of Mass Spectrometry ◽

10.1002/jms.1232 ◽

2007 ◽

Vol 42 (7) ◽

pp. 967-970 ◽

Cited By ~ 14

Author(s):

Guodong Chen ◽

Anatoliy Khusid ◽

Ibrahim Daaro ◽

Patrick Irish ◽

Birendra N. Pramanik

Keyword(s):

Mass Spectrometer ◽

Structural Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Trace Level ◽

Hybrid Mass Spectrometer ◽

Hydrogen Deuterium ◽

On Line ◽

Enol Tautomer

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A triaxial probe for on-line proteolysis coupled with hydrogen/deuterium exchange-electrospray mass spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2006.09.011 ◽

2007 ◽

Vol 18 (2) ◽

pp. 208-217 ◽

Cited By ~ 8

Author(s):

Maolian Chen ◽

Kelsey D. Cook ◽

Indu Kheterpal ◽

Ronald Wetzel

Keyword(s):

Mass Spectrometry ◽

Electrospray Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hydrogen Deuterium ◽

On Line

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Epitope mapping by amide hydrogen/deuterium exchange coupled with immobilization of antibody, on-line proteolysis, liquid chromatography and mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3921 ◽

2009 ◽

Vol 23 (5) ◽

pp. 639-647 ◽

Cited By ~ 84

Author(s):

Stephen J. Coales ◽

Steven J. Tuske ◽

Justine C. Tomasso ◽

Yoshitomo Hamuro

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Epitope Mapping ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Amide Hydrogen ◽

Hydrogen Deuterium ◽

On Line

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Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques

Metabolic Brain Disease ◽

10.1007/s11011-021-00763-y ◽

2021 ◽

Author(s):

Ahmad Shahir Sadr ◽

Zahra Abdollahpour ◽

Atousa Aliahmadi ◽

Changiz Eslahchi ◽

Mina Nekouei ◽

...

Keyword(s):

Mass Spectrometry ◽

Conformational Changes ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Alkali metal ion-induced conformation changes of methionine- and leucine enkephalin investigated by gas-phase hydrogen/deuterium exchange combined with theoretical calculations

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.130113 ◽

2021 ◽

Vol 1233 ◽

pp. 130113

Author(s):

Fangling Wu ◽

Yizhen Wang ◽

Yinjuan Chen ◽

Zhenhua Li ◽

Chuan-Fan Ding

Keyword(s):

Alkali Metal ◽

Gas Phase ◽

Metal Ion ◽

Theoretical Calculations ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Alkali Metal Ion ◽

Leucine Enkephalin ◽

Conformation Changes ◽

Hydrogen Deuterium

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Calculation of reaction rate constants for hydrogen–deuterium exchange reactions of methane catalysed by acid zeolites

Chemical Communications ◽

10.1039/b102249k ◽

2001 ◽

pp. 1108-1109 ◽

Cited By ~ 6

Author(s):

Ann M. Vos ◽

Robert A. Schoonheydt ◽

Frank De Proft ◽

Paul Geerlings

Keyword(s):

Rate Constants ◽

Reaction Rate ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Reactions ◽

Reaction Rate Constants ◽

Acid Zeolites ◽

Hydrogen Deuterium

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