Electrospray tandem mass spectrometry of alendronate analogues: fingerprints for characterization of new potential prodrugs

2008 ◽  
Vol 22 (15) ◽  
pp. 2287-2300 ◽  
Author(s):  
Julie Hardouin ◽  
Erwann Guénin ◽  
Christian Malosse ◽  
Michel Caron ◽  
Marc Lecouvey
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Electrospray Tandem Mass Spectrometry

scholarly journals Electrospray Tandem Mass Spectrometry of 3'-azido-2',3'dideoxythymidine and of a Novel Series of 3'-azido-2',3',4'-trideoxy-4'thio-5-halogenouridines and their Respective α-Anomers

1994 ◽  
Vol 12 (2) ◽  
pp. 69-83 ◽  
Author(s):  
Joseph Banoub ◽  
Emmanuel Gentil ◽  
Bougrine Tber ◽  
Nour-Eddine Fahmi ◽  
Gino Ronco ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Structural Characterization ◽  
Electrospray Mass Spectrometry ◽  
Low Energy ◽  
Tandem Mass ◽  
The Novel ◽  
Electrospray Tandem Mass Spectrometry ◽  
Protonated Molecules

Electrospray mass spectrometry has aided the structural characterization of 3'-azido-2',3'-dideoxythymidine (AZI) and the novel series of 3'-azido-2',3',4'trideoxy-4'-thio-S-(bromo, chi oro or fluoro )uridine nucleosides and their respective α.anomers. Low energy CAD MS/MS analysis of the protonated molecules [M+H]+confmned the predicted fragmentation route for AZT and a series of related 4'-thio-S-halogenouridines. This MSIMS study also provided characteristic fingerprint patterns which permitted differentiation of anomers within the series of 3'-azido-2' ,3' ,4' -trideoxy-4' -thio-S-halogenouridine nucleosides.

Characterization of the chromophores of pyoverdins and related siderophores by electrospray tandem mass spectrometry

BioMetals ◽  
2006 ◽  
Vol 20 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Herbert Budzikiewicz ◽  
Mathias Schäfer ◽  
Diana Uría Fernández ◽  
Sandra Matthijs ◽  
Pierre Cornelis
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Electrospray Tandem Mass Spectrometry
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