Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry

Zhongmin Guan; Xiaoyan Chen; Yinxiang Wang; Dafang Zhong

doi:10.1002/rcm.3599

Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3599 ◽

2008 ◽

Vol 22 (14) ◽

pp. 2176-2184 ◽

Cited By ~ 8

Author(s):

Zhongmin Guan ◽

Xiaoyan Chen ◽

Yinxiang Wang ◽

Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Antitumor Agent ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Metabolite identification of liguzinediol in dogs by ultra-flow liquid chromatography/tandem mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2014.06.029 ◽

2014 ◽

Vol 967 ◽

pp. 63-68 ◽

Cited By ~ 4

Author(s):

Chen-xiao Shan ◽

Wei Li ◽

Hong-mei Wen ◽

Xin-zhi Wang ◽

Xiao-wen Zhu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Liquid chromatography tandem mass spectrometry method for the quantitation of mycophenolate mofetil in human plasma: Application to a bioequivalence study and metabolite identification

Journal of Separation Science ◽

10.1002/jssc.201500779 ◽

2015 ◽

Vol 38 (20) ◽

pp. 3533-3544 ◽

Cited By ~ 2

Author(s):

Pankaj Partani ◽

Saurabh Manaswita Verma ◽

Tausif Monif

Keyword(s):

Mass Spectrometry ◽

Mycophenolate Mofetil ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Bioequivalence Study ◽

Tandem Mass ◽

Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8060 ◽

2018 ◽

Vol 32 (6) ◽

pp. 480-488 ◽

Cited By ~ 2

Author(s):

Wenchao Sun ◽

Khoa Dinh Nguyen ◽

William L. Fitch ◽

Samuel D. Banister ◽

Hongxiang Tang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Pharmacokinetics and metabolite identification of a novel VEGFR-2 and Src dual inhibitor 6-chloro-2-methoxy-N-(2-methoxybenzyl) acridin-9-amine in rats by liquid chromatography tandem mass spectrometry

Talanta ◽

10.1016/j.talanta.2011.11.061 ◽

2012 ◽

Vol 89 ◽

pp. 70-76 ◽

Cited By ~ 14

Author(s):

Yibao Jin ◽

Xudong Luan ◽

Hongxia Liu ◽

Chunmei Gao ◽

Shangfu Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Dual Inhibitor ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Determination and pharmacokinetic study of isothiouronium-modified pyrimidine-substituted curcumin analog (1G), a novel antitumor agent, in rat plasma by liquid chromatography–tandem mass spectrometry

Artificial Cells Nanomedicine and Biotechnology ◽

10.1080/21691401.2019.1602537 ◽

2019 ◽

Vol 47 (1) ◽

pp. 1505-1512

Author(s):

Jialin Sun ◽

Jinpeng Wang ◽

Lin Ma ◽

Tao Jiang ◽

Xiao Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pharmacokinetic Study ◽

Antitumor Agent ◽

Rat Plasma ◽

Tandem Mass ◽

Curcumin Analog ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-015-8893-x ◽

2015 ◽

Vol 407 (24) ◽

pp. 7319-7332 ◽

Cited By ~ 14

Author(s):

Samuel Chao Ming Yeo ◽

Vitaliy M. Sviripa ◽

Meng Huang ◽

Liliia Kril ◽

David S. Watt ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Biological Samples ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6559 ◽

2013 ◽

Vol 27 (11) ◽

pp. 1183-1195 ◽

Cited By ~ 5

Author(s):

Eunyoung Kim ◽

Hankyong Kim ◽

Kweehyun Suh ◽

Sechang Kwon ◽

Gwansun Lee ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tyrosine Kinase Inhibitor ◽

Pharmacokinetic Study ◽

Kinase Inhibitor ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Metabolite identification of bentysrepinine (Y101), a novel anti-HBV agent in rats using a five-step strategy based on a combined workflow with two different platforms of liquid chromatography–tandem mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2016.12.008 ◽

2017 ◽

Vol 1040 ◽

pp. 118-128 ◽

Cited By ~ 5

Author(s):

Huirong Fan ◽

Zhanxing Hu ◽

Ruixing Li ◽

Shiqi Dong ◽

Yuan Gu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Metabolism of a sulfur-containing heteroarotionoid antitumor agent, SHetA2, using liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3744 ◽

2008 ◽

Vol 22 (21) ◽

pp. 3371-3381 ◽

Cited By ~ 18

Author(s):

Zhongfa Liu ◽

Yilong Zhang ◽

Yousheng Frank Hua ◽

Joseph M. Covey ◽

Doris M. Benbrook ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Antitumor Agent ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Sulfur Containing

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High-throughput, accurate mass liquid chromatography/tandem mass spectrometry on a quadrupole time-of-flight system as a ‘first-line’ approach for metabolite identification studies

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3472 ◽

2008 ◽

Vol 22 (7) ◽

pp. 1053-1061 ◽

Cited By ~ 91

Author(s):

Philip R. Tiller ◽

Sean Yu ◽

Jose Castro-Perez ◽

Kerry L. Fillgrove ◽

Thomas A. Baillie

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Time Of Flight ◽

Metabolite Identification ◽

Tandem Mass ◽

First Line ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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