Two-dimensional liquid chromatography/mass spectrometry set-up for structural elucidation of metabolites in complex biological matrices

Michael Kiffe; Daniel Graf; Markus Trunzer

doi:10.1002/rcm.2923

Two-dimensional liquid chromatography/mass spectrometry set-up for structural elucidation of metabolites in complex biological matrices

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.2923 ◽

2007 ◽

Vol 21 (6) ◽

pp. 961-970 ◽

Cited By ~ 11

Author(s):

Michael Kiffe ◽

Daniel Graf ◽

Markus Trunzer

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Structural Elucidation ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Biological Matrices ◽

Chromatography Mass Spectrometry ◽

Set Up

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Comparison of a two-dimensional liquid chromatography/mass spectrometry approach with a chip-based nanoelectrospray device for structural elucidation of metabolites in a human ADME study using a quadrupole time-of-flight mass spectrometer

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.2918 ◽

2007 ◽

Vol 21 (6) ◽

pp. 937-944 ◽

Cited By ~ 11

Author(s):

Markus Trunzer ◽

Daniel Graf ◽

Michael Kiffe

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Mass Spectrometer ◽

Time Of Flight ◽

Structural Elucidation ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Flight Mass Spectrometer ◽

Chromatography Mass Spectrometry ◽

Adme Study

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Structural elucidation of in vivo metabolites of penehyclidine in rats by the method of liquid chromatography–mass spectrometry, gas chromatography–mass spectrometry and isotope ion cluster

Journal of Chromatography B ◽

10.1016/j.jchromb.2008.07.049 ◽

2008 ◽

Vol 873 (1) ◽

pp. 41-50 ◽

Cited By ~ 7

Author(s):

Ying Liu ◽

Mingming Wang ◽

Ming Xue ◽

Yuhang Li ◽

Xiaorong Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Liquid Chromatography ◽

Structural Elucidation ◽

Gas Chromatography Mass Spectrometry ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Ion Cluster

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Two-dimensional liquid chromatography/mass spectrometry/mass spectrometry separation of water-soluble metabolites

Journal of Chromatography A ◽

10.1016/j.chroma.2010.10.068 ◽

2010 ◽

Vol 1217 (52) ◽

pp. 8161-8166 ◽

Cited By ~ 33

Author(s):

Jacob N. Fairchild ◽

Krisztian Horvath ◽

Jessica R. Gooding ◽

Shawn R. Campagna ◽

Georges Guiochon

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Water Soluble ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Mass Spectrometry Mass Spectrometry

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An exploratory approach for an oriented development of an untargeted hydrophilic interaction liquid chromatography-mass spectrometry platform for polar metabolites in biological matrices

Journal of Chromatography A ◽

10.1016/j.chroma.2020.461807 ◽

2021 ◽

Vol 1637 ◽

pp. 461807

Author(s):

Elias Iturrospe ◽

Katyeny Manuela Da Silva ◽

Begoña Talavera Andújar ◽

Matthias Cuykx ◽

Joost Boeckmans ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Hydrophilic Interaction Liquid Chromatography ◽

Liquid Chromatography Mass Spectrometry ◽

Hydrophilic Interaction ◽

Biological Matrices ◽

Chromatography Mass Spectrometry ◽

Exploratory Approach ◽

Polar Metabolites

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Separation Orthogonality in Liquid Chromatography–Mass Spectrometry for Proteomic Applications: Comparison of 16 Different Two-Dimensional Combinations

Analytical Chemistry ◽

10.1021/acs.analchem.9b05407 ◽

2020 ◽

Vol 92 (5) ◽

pp. 3904-3912

Author(s):

Darien Yeung ◽

Benilde Mizero ◽

Daniel Gussakovsky ◽

Nicole Klaassen ◽

Ying Lao ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry

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Untargeted profiling of Glycyrrhiza glabra extract with comprehensive two-dimensional liquid chromatography-mass spectrometry using multi-segmented shift gradients in the second dimension: Expanding the metabolic coverage

Electrophoresis ◽

10.1002/elps.201700469 ◽

2018 ◽

Vol 39 (15) ◽

pp. 1993-2000 ◽

Cited By ~ 10

Author(s):

Yong Foo Wong ◽

Francesco Cacciola ◽

Soraya Fermas ◽

Solange Riga ◽

Darryl James ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Glycyrrhiza Glabra ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Untargeted Profiling

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Liquid Chromatography Mass Spectrometry Bioanalysis of Protein Therapeutics and Biomarkers in Biological Matrices

Mass Spectrometry in Drug Metabolism and Disposition ◽

10.1002/9780470929278.ch19 ◽

2011 ◽

pp. 613-644

Author(s):

Fumin Li ◽

Qin C. Ji

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Protein Therapeutics ◽

Liquid Chromatography Mass Spectrometry ◽

Biological Matrices ◽

Chromatography Mass Spectrometry

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Comprehensive Analysis of Short-, Medium-, and Long-Chain Acyl-Coenzyme A by Online Two-Dimensional Liquid Chromatography/Mass Spectrometry

Analytical Chemistry ◽

10.1021/acs.analchem.7b03659 ◽

2017 ◽

Vol 89 (23) ◽

pp. 12902-12908 ◽

Cited By ~ 10

Author(s):

Shuangyuan Wang ◽

Zhichao Wang ◽

Lina Zhou ◽

Xianzhe Shi ◽

Guowang Xu

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Coenzyme A ◽

Comprehensive Analysis ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Chain Acyl ◽

Acyl Coenzyme A ◽

Long Chain

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Preparative two-dimensional liquid chromatography/mass spectrometry for the purification of complex pharmaceutical samples

Journal of Chromatography A ◽

10.1016/j.chroma.2013.11.022 ◽

2014 ◽

Vol 1324 ◽

pp. 86-95 ◽

Cited By ~ 23

Author(s):

Yinong Zhang ◽

Lu Zeng ◽

Catherine Pham ◽

Rongda Xu

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Pharmaceutical Samples ◽

Chromatography Mass Spectrometry

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Detecting trace components in liquid chromatography/mass spectrometry data sets with two-dimensional wavelets

10.1117/12.732910 ◽

2007 ◽

Author(s):

Duane C. Compton ◽

Robert R. Snapp

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Mass Spectrometry Data ◽

Data Sets ◽

Two Dimensional ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Trace Components

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